Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy

Ingle, Lee; Rigby, Alan S.; Carroll, Sean; Butterly, Ron; King, Rod F.; Cooke, Carlton B.; Cleland, John G.J.F.; Clark, Andrew L.

Abstract

Background: Increasing body mass index, cholesterol and body fat are associated with a better prognosis in patients with left ventricular systolic dysfunction (LVSD). Beta-blocker usage is associated with changes in body composition and increased body fat. The present study investigated 12-month changes in body composition in patients with LVSD initiated on beta-blocker therapy. Methods: The relation between beta-blocker use and body composition was evaluated in 91 patients (75% male) with LVSD. Body composition was assessed by bioelectrical impedance. Results: Seventeen patients died during the study period. There was no statistical difference among beta-blocker usage, beta-blocker type, or changes in body fat, basal metabolic rate, impedance, fat-free mass, fat mass and total body water. There were no significant differences between any of these measures and beta-blocker usage. Conclusion: After 12 months, changes in body composition were not found to be influenced by initiation of beta-blocker therapy in patients with LVSD. © 2007 Pulsus Group Inc. All rights reserved.

Citation

Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., Cleland, J. G., & Clark, A. L. (2007). Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy. Experimental and Clinical Cardiology, 12(1), 46-47

• Journal Article Type: Article
• Acceptance Date: Sep 5, 2006
• Publication Date: Apr 19, 2007
• Deposit Date: May 7, 2019
• Journal: Experimental and Clinical Cardiology
• Print ISSN: 1205-6626
• Publisher: Cardiology Academic Press
• Peer Reviewed: Peer Reviewed
• Volume: 12
• Issue: 1
• Pages: 46-47
• Keywords: Body fat; Chronic heart failure; Fat-free mass; Fat mass
• Public URL: https://hull-repository.worktribe.com/output/527339
• Additional Information: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359626/