Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy

Ingle, Lee; Rigby, Alan S.; Carroll, Sean; Butterly, Ron; King, Rod F.; Cooke, Carlton B.; Cleland, John G.J.F.; Clark, Andrew L.

Abstract

Background: Increasing body mass index, cholesterol and body fat are associated with a better prognosis in patients with left ventricular systolic dysfunction (LVSD). Beta-blocker usage is associated with changes in body composition and increased body fat. The present study investigated 12-month changes in body composition in patients with LVSD initiated on beta-blocker therapy. Methods: The relation between beta-blocker use and body composition was evaluated in 91 patients (75% male) with LVSD. Body composition was assessed by bioelectrical impedance. Results: Seventeen patients died during the study period. There was no statistical difference among beta-blocker usage, beta-blocker type, or changes in body fat, basal metabolic rate, impedance, fat-free mass, fat mass and total body water. There were no significant differences between any of these measures and beta-blocker usage. Conclusion: After 12 months, changes in body composition were not found to be influenced by initiation of beta-blocker therapy in patients with LVSD. © 2007 Pulsus Group Inc. All rights reserved.

Citation

Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., …Clark, A. L. (2007). Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy. Experimental and Clinical Cardiology, 12(1), 46-47

• Journal Article Type: Article
• Acceptance Date: Sep 5, 2006
• Publication Date: Apr 19, 2007
• Deposit Date: May 7, 2019
• Journal: Experimental and Clinical Cardiology
• Print ISSN: 1205-6626
• Publisher: Cardiology Academic Press
• Peer Reviewed: Peer Reviewed
• Volume: 12
• Issue: 1
• Pages: 46-47
• Keywords: Body fat; Chronic heart failure; Fat-free mass; Fat mass
• Public URL: https://hull-repository.worktribe.com/output/527339
• Additional Information: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359626/