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Does soluble intercellular adhesion molecule-1 (ICAM-1) affect neutrophil activation and adhesion following ischaemia-reperfusion? (1999)
Journal Article
Spark, J., Scott, D., Chetter, I., Guillou, P., & Kester, R. (1999). Does soluble intercellular adhesion molecule-1 (ICAM-1) affect neutrophil activation and adhesion following ischaemia-reperfusion?. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 17(2), 115-120. https://doi.org/10.1053/ejvs.1998.0710

Objective: to examine the effect of reperfusion plasma and sICAM-1 on neutrophil integrin expression and neutrophil adhesion to determine if sICAM-1 has a potential role in the regulation of neutrophil adhesion. Materials: twenty-seven patients, 17 m... Read More about Does soluble intercellular adhesion molecule-1 (ICAM-1) affect neutrophil activation and adhesion following ischaemia-reperfusion?.

Does angioplasty improve the quality of life for claudicants?: A prospective study (1999)
Journal Article
Chetter, I. C., Spark, J. I., Scott, D. J. A., & Kester, R. C. (1999). Does angioplasty improve the quality of life for claudicants?: A prospective study. Annals of vascular surgery, 13(1), 93-103. https://doi.org/10.1007/s100169900226

This study aims to analyze the impact of percutaneous transluminal angioplasty (PTA) for claudication on patients' quality of life (QOL). The patients in this study included 108 claudicants, 74 men and 34 women, with a median age of 67 years (range 4... Read More about Does angioplasty improve the quality of life for claudicants?: A prospective study.

Percutaneous transluminal angioplasty for intermittent claudication: Evidence on which to base the medicine (1998)
Journal Article
Chetter, I., Spark, J., Kent, P., Berridge, D., Scott, D., & Kester, R. (1998). Percutaneous transluminal angioplasty for intermittent claudication: Evidence on which to base the medicine. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 16(6), 477-484. https://doi.org/10.1016/s1078-5884%2898%2980237-2

Objectives:this study aims to assess the impact of PTA on the quality of life (QoL) of claudicants and to analyse which patients and which arterial lesions derive the most benefit.Design:a prospective observational study.Materials:one hundred and sev... Read More about Percutaneous transluminal angioplasty for intermittent claudication: Evidence on which to base the medicine.

Prospective analysis of quality of life in patients following infrainguinal reconstruction for chronic critical ischaemia (1998)
Journal Article
Chetter, I., Spark, J., Scott, D., Kent, P., Berridge, D., & Kester, R. (1998). Prospective analysis of quality of life in patients following infrainguinal reconstruction for chronic critical ischaemia. British journal of surgery, 85(7), 951-955. https://doi.org/10.1046/j.1365-2168.1998.00752.x

BackgroundThe aims of this prospective study were to analyse the health-related quality of life (QOL) changes associated with infrainguinal arterial reconstruction for chronic critical limb ischaemia (CLI) and to assess the impact of graft patency an... Read More about Prospective analysis of quality of life in patients following infrainguinal reconstruction for chronic critical ischaemia.

Reduced total antioxidant capacity predicts ischaemia-reperfusion injury after femorodistal bypass (1998)
Journal Article
Spark, J., Chetter, I., Gallavin, I., Kester, R., Guillou, P., & Scott, D. (1998). Reduced total antioxidant capacity predicts ischaemia-reperfusion injury after femorodistal bypass. British journal of surgery, 85(2), 221-225. https://doi.org/10.1046/j.1365-2168.1998.00542.x

BackgroundAntioxidant defence systems are essential to protect the body from harmful free radicals released following ischaemia-reperfusion. The aim of this study was to examine the total antioxidant capacity (TAC) of patients with chronic critical l... Read More about Reduced total antioxidant capacity predicts ischaemia-reperfusion injury after femorodistal bypass.

Allogeneic versus autologous blood during abdominal aortic aneurysm surgery (1997)
Journal Article
Spark, J., Chetter, I., Kester, R., & Scott, D. (1997). Allogeneic versus autologous blood during abdominal aortic aneurysm surgery. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 14(6), 482-486. https://doi.org/10.1016/s1078-5884%2897%2980128-1

Objectives: To determine if cell-salvaged autologous blood can serve as an alternative to homologous blood, and to examine the incidence of infected complications and length of postoperative stay. Design: A prospective randomised study comprising aut... Read More about Allogeneic versus autologous blood during abdominal aortic aneurysm surgery.

The hand arm vibration syndrome: A review (1997)
Journal Article
Kester, R. C., Kent, P. J., & Chetter, I. C. (1997). The hand arm vibration syndrome: A review. Cardiovascular Surgery -Oxford-, 6(1), 1-9. https://doi.org/10.1016/S0967-2109%2897%2900090-2

Since its first description over eight decades ago, the hand arm vibration syndrome - vibration white finger as it was previously known - has become one of the most common prescribed diseases in the industrialized world. This article is intended to p... Read More about The hand arm vibration syndrome: A review.

Correlating clinical indicators of lower-limb ischaemia with quality of life (1997)
Journal Article
Chetter, I., Dolan, P., Spark, J., Scott, D., & Kester, R. (1997). Correlating clinical indicators of lower-limb ischaemia with quality of life. Cardiovascular Surgery -Oxford-, 5(4), 361-366. https://doi.org/10.1016/s0967-2109%2897%2900011-2

The objectives of the study were to analyse the impact of increasing lower-limb ischaemia upon quality of life and to assess the correlation between clinical indicators of lower-limb ischaemia and such quality. A prospective observational study of a... Read More about Correlating clinical indicators of lower-limb ischaemia with quality of life.

Quality of life analysis in patients with lower limb ischaemia: Suggestions for European standardisation (1997)
Journal Article
Chetter, I., Spark, J., Dolan, P., Scott, D., & Kester, R. (1997). Quality of life analysis in patients with lower limb ischaemia: Suggestions for European standardisation. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 13(6), 597-604. https://doi.org/10.1016/s1078-5884%2897%2980070-6

Introduction and Objectives:In this era of evidence-based medicine and limited resources we seem obliged, on clinical and economic grounds, to demonstrate that we improve not only patient survival but also the quality of patients' lives. This study a... Read More about Quality of life analysis in patients with lower limb ischaemia: Suggestions for European standardisation.

The regulation of neutrophil activation and adhesion during femorodistal bypass surgery (1997)
Journal Article
Spark, J., Chetter, I., Kester, R., Guillou, P., & Scott, D. (1997). The regulation of neutrophil activation and adhesion during femorodistal bypass surgery. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 13(4), 407-412. https://doi.org/10.1016/s1078-5884%2897%2980085-8

Objective:To determine the effect that revascularising chronic critically ischaemic legs has no neutrophil activation and adhesion.Design:Prospective clinical study.Setting:University Hospital.Materials:Twenty-five patients, 16 men and nine women und... Read More about The regulation of neutrophil activation and adhesion during femorodistal bypass surgery.

Hyperbaric oxygen normalised microvascular reflexes in patients with peripheral arterial disease
Presentation / Conference
Abidia, A., Kuhan, G., McCollum, P., & Chetter, I. Hyperbaric oxygen normalised microvascular reflexes in patients with peripheral arterial disease. Paper presented at Undersea and Hyperbaric Medical Society (UHMS) Annual Meeting

BACKGROUND: The abnormal microvascular reflexes seen in vascular patients are of importance in the pathogenesis of complications. We investigated the influence of oxygen on two reflexes, the vasoconstrictive response to leg dependency (VCD) and the v... Read More about Hyperbaric oxygen normalised microvascular reflexes in patients with peripheral arterial disease.