Professor Ian Chetter's Outputs (176)

Peak wall stress measurement in elective and acute abdominal aortic aneurysms (2007)
Journal Article
Heng, M. S., Fagan, M. J., Collier, J. W., Desai, G., McCollum, P. T., & Chetter, I. C. (2008). Peak wall stress measurement in elective and acute abdominal aortic aneurysms. Journal of vascular surgery, 47(1), 17-22. https://doi.org/10.1016/j.jvs.2007.09.002

Background: Abdominal aortic aneurysm (AAA) rupture occurs when wall stress exceeds wall strength. Engineering principles suggest that aneurysm diameter is only one aspect of its geometry that influences wall stress. Finite element analysis considers... Read More about Peak wall stress measurement in elective and acute abdominal aortic aneurysms.

Cutaneous hyperpigmentation after endovenous laser therapy: a case report and literature review (2007)
Journal Article
Mekako, A., & Chetter, I. (2007). Cutaneous hyperpigmentation after endovenous laser therapy: a case report and literature review. Annals of vascular surgery, 21(5), 637-639. https://doi.org/10.1016/j.avsg.2007.03.013

Endovenous laser therapy (EVLT) for the treatment of varicose veins has been shown to be effective and relatively safe. Reported complications are few and transient. Whereas it is not uncommon to have cutaneous hyperpigmentation following treatment m... Read More about Cutaneous hyperpigmentation after endovenous laser therapy: a case report and literature review.

Plasma tissue factor is a predictor for restenosis after femoropopliteal angioplasty (2007)
Journal Article
Ray, B., Chetter, I. C., Lee, H. L. D., Ettelaie, C., & McCollum, P. T. (2007). Plasma tissue factor is a predictor for restenosis after femoropopliteal angioplasty. British journal of surgery, 94(9), 1092-1095. https://doi.org/10.1002/bjs.5759

Background:In vitro studies suggest an association between raised levels of tissue factor and restenosis after coronary percutaneous transluminal angioplasty (PTA). This prospective, controlled study examined the association between plasma tissue fac... Read More about Plasma tissue factor is a predictor for restenosis after femoropopliteal angioplasty.

Differential functions of tissue factor in the trans-activation of cellular signalling pathways (2006)
Journal Article
Ettelaie, C., Li, C., Collier, M. E. W., Pradier, A., Frentzou, G. A., Wood, C. G., Chetter, I. C., McCollum, P. T., Bruckdorfer, K. R., & James, N. J. (2007). Differential functions of tissue factor in the trans-activation of cellular signalling pathways. Atherosclerosis, 194(1), 88-101. https://doi.org/10.1016/j.atherosclerosis.2006.10.010

In this study we examined the ability of tissue factor (TF) alone, or in conjunction with factor VIIa, factor Xa and TFPI in activating a number of key signalling pathways associated with cellular growth, stress and differentiation responses in human... Read More about Differential functions of tissue factor in the trans-activation of cellular signalling pathways.

A nonrandomised controlled trial of endovenous laser therapy and surgery in the treatment of varicose veins (2006)
Journal Article
Mekako, A. I., Hatfield, J., Bryce, J., Lee, D., McCollum, P. T., & Chetter, I. (2006). A nonrandomised controlled trial of endovenous laser therapy and surgery in the treatment of varicose veins. Annals of vascular surgery, 20(4), 451-457. https://doi.org/10.1007/s10016-006-9095-y

Endovenous laser therapy (EVLT) is a minimally invasive treatment for varicose veins. This study compares early quality-of-life (QoL) outcomes following EVLT and surgery. Two nonrandomized groups were studied: an EVLT group with 70 patients, median a... Read More about A nonrandomised controlled trial of endovenous laser therapy and surgery in the treatment of varicose veins.

Response to letter to editor re: Mehta T, Venkata Subramaniam A, Chetter I, McCollum P. Assessing the validity and responsiveness of disease-specific quality of life instruments in intermittent claudication. Eur J Vasc Eudovasc Surg 2006;31:46-52 (2006)
Journal Article
Mehta, T. A., & Chetter, I. C. (2006). Response to letter to editor re: Mehta T, Venkata Subramaniam A, Chetter I, McCollum P. Assessing the validity and responsiveness of disease-specific quality of life instruments in intermittent claudication. Eur J Vasc Eudovasc Surg 2006;31:46-52. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 32(1), 110. https://doi.org/10.1016/j.ejvs.2006.02.005

Combined endovenous laser therapy and ambulatory phlebectomy: refinement of a new technique (2006)
Journal Article
Mekako, A., Hatfield, J., Bryce, J., Lee, D., Heng, M., McCollum, P., & Chetter, I. (2006). Combined endovenous laser therapy and ambulatory phlebectomy: refinement of a new technique. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 32(6), 725-729. https://doi.org/10.1016/j.ejvs.2006.06.002

Objective. Sclerotherapy (IS) or ambulatory phlebectomy (AP) are required as subsequent interventions in majority of cases following endovenous laser therapy (EVLT). We assessed whether AP performed concomitantly with EVLT (EVLTAP), is effective, acc... Read More about Combined endovenous laser therapy and ambulatory phlebectomy: refinement of a new technique.

Randomized clinical trial comparing multiple stab incision phlebectomy and transilluminated powered phlebectomy for varicose veins (2006)
Journal Article
Chetter, I., Mylankal, K. J., Hughes, H., & Fitridge, R. (2006). Randomized clinical trial comparing multiple stab incision phlebectomy and transilluminated powered phlebectomy for varicose veins. British journal of surgery, 93(2), 169-174. https://doi.org/10.1002/bjs.5261

Background: The aim was to compare early postoperative subjective outcome measures in a randomized trial of multiple stab incision phlebectomy (MSIP) and transilluminated powered phlebectomy (TIPP) for the treatment of varicose veins. Methods: Patien... Read More about Randomized clinical trial comparing multiple stab incision phlebectomy and transilluminated powered phlebectomy for varicose veins.

Assessing the validity and responsiveness of disease-specific quality of life instruments in intermittent claudication (2005)
Journal Article
Mehta, T., Venkatasubramaniam, A., Chetter, I., & McCollum, P. (2006). Assessing the validity and responsiveness of disease-specific quality of life instruments in intermittent claudication. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 31(1), 46 - 52. https://doi.org/10.1016/j.ejvs.2005.08.028

PurposeTo recommend a suitable disease-specific quality of life (QOL) instrument for use in intermittent claudication (IC) based on validity and responsiveness.MethodsSeventy claudicants completed two generic (SF36 and EUROQOL) and three disease-spec... Read More about Assessing the validity and responsiveness of disease-specific quality of life instruments in intermittent claudication.

Heat shock proteins in vascular disease - a review (2005)
Journal Article
Mehta, T., Greenman, J., Ettelaie, C., Venkatasubramaniam, A., Chetter, I., & McCollum, P. (2005). Heat shock proteins in vascular disease - a review. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 29(4), 395-402. https://doi.org/10.1016/j.ejvs.2005.01.005

Introduction
There is growing evidence that heat shock proteins (HSPs), a family of stress-inducible proteins may be involved in the pathogenesis of atherosclerotic vascular diseases. Here, we systematically review the evidence behind this notion.... Read More about Heat shock proteins in vascular disease - a review.

Randomised controlled trials (RCTs) to evaluate complex healthcare interventions - A case study (2004)
Journal Article
Wong, I. C. K. (2004). Randomised controlled trials (RCTs) to evaluate complex healthcare interventions - A case study. Pharmacy world & science : PWS, 26(5), 247-252. https://doi.org/10.1023/B%3APHAR.0000042920.34663.04

In 2001 the UK National Health Service (NHS) issued its National Service Framework for the Elderly (NSF-E). This identified the elderly as a vulnerable group needing a high level of pharmaceutical intervention. As such, the NSF-E outlined plans to im... Read More about Randomised controlled trials (RCTs) to evaluate complex healthcare interventions - A case study.

A Comparative Study of Aortic Wall Stress Using Finite Element Analysis for Ruptured and Non-ruptured Abdominal Aortic Aneurysms*1 (2004)
Journal Article
VENKATASUBRAMANIAM, A., FAGAN, M., MEHTA, T., MYLANKAL, K., RAY, B., KUHAN, G., CHETTER, I., & MCCOLLUM, P. (2004). A Comparative Study of Aortic Wall Stress Using Finite Element Analysis for Ruptured and Non-ruptured Abdominal Aortic Aneurysms*1. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 28(2), 168-176. https://doi.org/10.1016/S1078-5884%2804%2900178-9

Background. The decision to repair an asymptomatic abdominal aortic aneurysm (AAA) is currently based on diameter (greater than or equal to 5.5 cm) alone. However, aneurysms less than 5.5 cm do rupture while some reach greater than 5.5 cm without rup... Read More about A Comparative Study of Aortic Wall Stress Using Finite Element Analysis for Ruptured and Non-ruptured Abdominal Aortic Aneurysms*1.

Temporary balloon catheter occlusion for control of haemorrhage following penetrating axillary artery injury (2004)
Journal Article
Mehta, T., Venkata Subramaniam, A., Chetter, I., Nicholson, A., & Wilkinson, A. (2004). Temporary balloon catheter occlusion for control of haemorrhage following penetrating axillary artery injury. European Journal of Vascular and Endovascular Surgery Extra, 8(2), 29-30. https://doi.org/10.1016/j.ejvsextra.2004.05.014

Penetrating injuries of the axillary artery are uncommon. Their repair can be difficult in the presence of torrential haemorrhage, which obscures the surgical field. We describe the use of interventional radiology for temporary control of bleeding to... Read More about Temporary balloon catheter occlusion for control of haemorrhage following penetrating axillary artery injury.

A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms (2004)
Journal Article
Venkatasubramaniam, A. K., Fagan, M. J., Mehta, T., Mylankal, K. J., Ray, B., Kuhan, G., Chetter, I. C., & McCollum, P. T. (2004). A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 28(2), 168-176. https://doi.org/10.1016/j.ejvs.2004.03.029

Background. The decision to repair an asymptomatic abdominal aortic aneurysm (AAA) is currently based on diameter (≥5.5 cm) alone. However, aneurysms less than 5.5 cm do rupture while some reach greater than 5.5 cm without rupturing. Hence the need t... Read More about A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms.

The value of abdominal examination in the diagnosis of abdominal aortic aneurysm (2004)
Journal Article
Venkatasubramaniam, A., Mehta, T., Chetter, I., Bryce, J., Renwick, P., Johnson, B., Wilkinson, A., & McCollum, P. (2004). The value of abdominal examination in the diagnosis of abdominal aortic aneurysm. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 27(1), 56-60. https://doi.org/10.1016/j.ejvs.2003.09.006

Background. There is considerable variability in the reported value of clinical examination in the diagnosis of abdominal aortic aneurysms (AAA). This study aims to assess accuracy of abdominal examination by a doctor, a nurse and the patient in the... Read More about The value of abdominal examination in the diagnosis of abdominal aortic aneurysm.

Disease-specific quality of life assessment in intermittent claudication: review (2003)
Journal Article
Mehta, T., Subramaniam, A., Chetter, I., & McCollum, P. (2003). Disease-specific quality of life assessment in intermittent claudication: review. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 25(3), 202-208. https://doi.org/10.1053/ejvs.2002.1837

Objectives: intermittent claudication (IC) is a common condition that has a major impact on the patients' quality of life (QoL). Generic QoL instruments often lack sensitivity to detect small but clinically significant variation in QoL. Disease-speci... Read More about Disease-specific quality of life assessment in intermittent claudication: review.

A Bayesian hierarchical approach to comparative audit for carotid surgery (2002)
Journal Article
Kuhan, G., Marshall, E., Abidia, A., Chetter, I., & McCollum, P. (2002). A Bayesian hierarchical approach to comparative audit for carotid surgery. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 24(6), 505-510. https://doi.org/10.1053/ejvs.2002.1763

Objectives: the aim of this study was to illustrate how a Bayesian hierarchical modelling approach can aid the reliable comparison of outcome rates between surgeons. Design: retrospective analysis of prospective and retrospective data. Materials: bin... Read More about A Bayesian hierarchical approach to comparative audit for carotid surgery.

How effective is acute normovolaemic haemodilution in femoro-distal bypass surgery? (2002)
Journal Article
Spark, J., Chetter, I., Kester, R., & Scott, D. (2002). How effective is acute normovolaemic haemodilution in femoro-distal bypass surgery?. Cardiovascular Surgery -Oxford-, 10(5), 460-463. https://doi.org/10.1016/s0967-2109%2802%2900060-1

Background: Recent guidelines have emphasised the use of autologous blood in the surgical setting. The aim of this study was to analyse the efficacy and efficiency of acute normovolaemic haemodilution (ANH) as a blood conservation intervention in pat... Read More about How effective is acute normovolaemic haemodilution in femoro-distal bypass surgery?.

POSSUM and P-POSSUM overpredict mortality for carotid endarterectomy (2002)
Journal Article
Kuhan, G., Abidia, A. F., Wijesinghe, L. D., Chetter, I. C., Johnson, B. F., Wilkinson, A. .., Renwick, P. M., & McCollum, P. T. (2002). POSSUM and P-POSSUM overpredict mortality for carotid endarterectomy. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 23(3), 209-211. https://doi.org/10.1053/ejvs.2001.1557

Objectives: the aim was to test the predictive accuracy of POSSUM and P-POSSUM on patients undergoing CEA. Design: retrospective and prospective study. Materials: 499 CEAs performed by four vascular surgeons from a single unit from 1992-99. The media... Read More about POSSUM and P-POSSUM overpredict mortality for carotid endarterectomy.

Risk modelling study for carotid endarterectomy (2001)
Journal Article
Kuhan, G., Gardiner, E. D., Abidia, A. F., Chetter, I. C., Renwick, P. M., Johnson, B. F., Wilkinson, A. R., & McCollum, P. T. (2001). Risk modelling study for carotid endarterectomy. British journal of surgery, 88(12), 1590-1594. https://doi.org/10.1046/j.0007-1323.2001.01938.x

Background: The aims of this study were to identify factors that influence the risk of stroke or death following carotid endarterectomy (CEA) and to develop a model to aid in comparative audit of vascular surgeons and units. Methods: A series of 839... Read More about Risk modelling study for carotid endarterectomy.