Hemoglobin in the brain frontal lobe tissue of patients with Alzheimer's disease is susceptible to reactive nitrogen species-mediated oxidative damage
(2025)
Journal Article
Smallwood, M. J., Alghayth, M. A., Knight, A. R., Tveen-Jensen, K., Pitt, A. R., Spickett, C. M., Llewellyn, D., Pula, G., Wearn, A., Vanhatalo, A., Jones, A. M., Francis, P., Coulthard, E., Kehoe, P. G., & Winyard, P. G. (2025). Hemoglobin in the brain frontal lobe tissue of patients with Alzheimer's disease is susceptible to reactive nitrogen species-mediated oxidative damage. Redox Biology, 82, Article 103612. https://doi.org/10.1016/j.redox.2025.103612
Brain inflammation in Alzheimer's disease (AD) involves reactive nitrogen species (RNS) generation. Protein contents of 3-nitrotyrosine, a product of RNS generation, were assessed in frontal lobe brain homogenates from patients with AD, patients with...
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