Dr Simon Calaminus
| Post Nominals | BSc, PhD, SFHEA |
|---|---|
| Biography | I completed my PhD in Platelet Biology from 2004-2007 at the University of Birmingham under the supervision of Professor Steve Watson. During this time I specialised in the platelet actin cytoskeleton and worked alongside Professor Laura Machesky to identify the actin structure, the actin nodule within platelets. I then worked as a post doctoral scientist for Professor Laura Machesky at the Beatson Institute in Glasgow from 2007-2012. Here I worked both with megakaryocytes to identify the role of podosomes, and also with cancer cells understanding the role of the Wash complex within receptor recycling. In 2012 I moved to the University of Hull as a lecturer, where I was promoted to senior lecturer in 2018. |
| Research Interests | The Calaminus lab investigates how platelets respond and activate to a range of different agonists and inhibitors to fully understand the range of functions that platelet complete within the body. To do this we use a range of assays: platelet spreading, in vitro thrombus formation, FACs analysis, western blotting and platelet aggregation. We aim to not only understand how platelet respond to natural environments, but also how addition of external pollutants such as microplastics then affect and disturb these environments leading to platelet dysfunction. |
| Teaching and Learning | I am the programme director for the MSc in Pharmacology and Drug Development in HYMS. This provides students with not only the opportunity to delve deeply into Pharmacology but to do this alongside external experts from industry and the NHS to ensure students get a full understanding of the role and power of pharmacology I teach Phase 1 MBBS students and Biomedical Science Pharmacology in a lecture and seminar format |
| Scopus Author ID | 13609379200 |
| PhD Supervision Availability | Yes |
| PhD Topics | Platelet Biology If self funded students wish to approach me to investigate the possibility of completing a PhD, then please email me directly using simon.calaminus@hyms.ac.uk |