Dr Chao Huang's Outputs (8)

Simplification or simulation: power calculation in clinical trials (2021)
Journal Article
Huang, C., Li, P., & Martin, C. R. (2022). Simplification or simulation: power calculation in clinical trials. Contemporary clinical trials, 113, Article 106663. https://doi.org/10.1016/j.cct.2021.106663

Background and objectives: A justifiable sample size is essential at trial design stage. Generally this task is completed by forming the main research question into a statistical procedure and then implementing the published formulae or software pack... Read More about Simplification or simulation: power calculation in clinical trials.

Correction to: Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum (International Journal of Obesity, (2021), 45, 8, (1728-1739), 10.1038/s41366-021-00835-0) (2021)
Journal Article
Simpson, S. A., Coulman, E., Gallagher, D., Jewell, K., Cohen, D., Newcombe, R. G., Huang, C., Robles-Zurita, J. A., Busse, M., Owen-Jones, E., Duncan, D., Williams, N., Stanton, H., Avery, A., McIntosh, E., & Playle, R. (2022). Correction to: Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum (International Journal of Obesity, (2021), 45, 8, (1728-1739), 10.1038/s41366-021-00835-0). International journal of obesity, 46, Article 242. https://doi.org/10.1038/s41366-021-00976-2

The original version of this article unfortunately contained an error in an author name. Jose Antonio Robles should be changed to José Antonio Robles-Zurita. The authors apologize for the error. The original article has been corrected.

The prognostic value of respiratory symptoms and performance status in ambulatory cancer patients and unsuspected pulmonary embolism; analysis of an international, prospective, observational cohort study (2021)
Journal Article
Maraveyas, A., Kraaijpoel, N., Bozas, G., Huang, C., Mahé, I., Bertoletti, L., Bartels-Rutten, A., Beyer-Westendorf, J., Constans, J., Iosub, D., Couturaud, F., Muñoz, A. J., Biosca, M., Lerede, T., van Es, N., Di Nisio, M., Accassat, S., The UPE investigators, Aquilanti, S., Assaf, J. D., …Zumàrraga Cuesta, A. (2021). The prognostic value of respiratory symptoms and performance status in ambulatory cancer patients and unsuspected pulmonary embolism; analysis of an international, prospective, observational cohort study. Journal of thrombosis and haemostasis : JTH, 19(11), 2791-2800. https://doi.org/10.1111/jth.15489

Background: Optimal risk stratification of unsuspected pulmonary embolism (UPE) in ambulatory cancer patients (ACPs) remains unclear. Existing clinical predictive rules (CPRs) are derived from retrospective databases and have limitations. The UPE reg... Read More about The prognostic value of respiratory symptoms and performance status in ambulatory cancer patients and unsuspected pulmonary embolism; analysis of an international, prospective, observational cohort study.

Urinary iodine concentration and radioactive iodine therapeutic response in patients with differentiated thyroid cancer (2021)
Journal Article
Jiang, Y., Jin, J., Fan, J., Huang, C., Jia, Q., Tan, J., He, X., Zheng, X., Zhao, Y., Zhang, Q., Meng, Z., & Wang, Y. (2021). Urinary iodine concentration and radioactive iodine therapeutic response in patients with differentiated thyroid cancer. Biomarkers in Medicine, 15(11), 879-890. https://doi.org/10.2217/bmm-2020-0745

Aim: Urinary iodine concentration (UIC) may assess radioactive iodine ablation. Materials & methods: According the 2015 American Thyroid Association guidelines, patients were categorized into low-to intermediate-risk or high-risk groups. The iodine c... Read More about Urinary iodine concentration and radioactive iodine therapeutic response in patients with differentiated thyroid cancer.

The Tokophobia Severity Scale (TSS): measurement model, power and sample size considerations (2021)
Journal Article
Martin, C. R., Jones, C., Huang, C., Jomeen, J., Boubert, L., & Marshall, C. A. (in press). The Tokophobia Severity Scale (TSS): measurement model, power and sample size considerations. Journal of reproductive and infant psychology, https://doi.org/10.1080/02646838.2021.1931070

Objective: To examine the measurement model of the Tokophobia Severity Scale and consider issues of statistical power and sample size from the original instrument development study. Background: Fear of childbirth (FoC) and tokophobia represents an ar... Read More about The Tokophobia Severity Scale (TSS): measurement model, power and sample size considerations.

Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum (2021)
Journal Article
Robles, J. A., Simpson, S. A., Coulman, E., Gallagher, D., Jewell, K., Cohen, D., Newcombe, R. G., Huang, C., Robles-Zurita, J. A., Busse, M., Owen-Jones, E., Duncan, D., Williams, N., Stanton, H., Avery, A., McIntosh, E., & Playle, R. (2021). Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum. International journal of obesity, 45(8), 1728-1739. https://doi.org/10.1038/s41366-021-00835-0

Objective: To assess whether a weight management intervention for pregnant women with obesity was effective in reducing body mass index (BMI) 12 months after giving birth. Methods: Pragmatic, cluster randomised controlled trial (RCT) with embedded co... Read More about Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum.

Do patient characteristics matter when calculating sample size for eczema clinical trials? (2021)
Journal Article
Howells, L., Gran, S., Chalmers, J. R., Stuart, B., Santer, M., Bradshaw, L., Gaunt, D. M., Ridd, M. J., Gerbens, L. A., Spuls, P. I., Huang, C., Francis, N. A., & Thomas, K. S. (2021). Do patient characteristics matter when calculating sample size for eczema clinical trials?. Skin Health and Disease, 1(3), Article e42. https://doi.org/10.1002/ski2.42

Background: The Patient-Oriented Eczema Measure (POEM) is the core outcome instrument recommended for measuring patient-reported atopic eczema symptoms in clinical trials. To ensure that the statistical significance of clinical trial results is meani... Read More about Do patient characteristics matter when calculating sample size for eczema clinical trials?.

Prostate cancer: unmet supportive and palliative care needs: national survey of patients and family carers (2021)
Journal Article
Johnson, M. J., Huang, C., Chen, H., Jones, L., & Twiddy, M. (2021). Prostate cancer: unmet supportive and palliative care needs: national survey of patients and family carers. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2021-003438

Objectives: Men living with prostate cancer have supportive and palliative needs. However, few studies detail unmet needs (vs quality of life measurement) or include data from those with advanced disease. We aimed to identify unmet needs of people li... Read More about Prostate cancer: unmet supportive and palliative care needs: national survey of patients and family carers.