Endometriosis and bleeding disorders: detection of endometriosis and identification of new treatment strategies Sep 1, 2024 - Aug 31, 2025
Endometriosis is a chronic, debilitating gynaecological disease that affects 1 in 10 women worldwide. In the UK the average wait for a diagnosis of endometriosis is 8 years which has not improved in over a decade. Due to the lack of an accurate non-...
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Dr Chao Huang's Projects (18)
HIKE: Development of a commercial urine test for the earlier detection of endometriosis Jul 1, 2023 - Mar 31, 2025
Endometriosis is a chronic incurable condition that is associated with debilitating pain and subfertility. It affects 190 million women worldwide, takes 8 years to diagnose and costs the UK economy £8.2 billion each year in loss of work (predomi...
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Prevalence of cirrhosis and its related complications amongst patients with hereditary haemochromatosis in England Apr 1, 2023 - Mar 31, 2026
This is a study with Robert Driver and Simran Singh from York Teaching hospital. The project is about Prevalence of cirrhosis and its related complications amongst patients with hereditary haemochromatosis in England. And we will require the NHS digi...
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BREEZE 2: A randomised controlled trial of a complex intervention to manage breathlessness in pulmonary fibrosis Apr 1, 2024 - Mar 31, 2026
Full trial based on BREEZE feasibility trial
Mortality Risk Prediction of ICU Patients with Sepsis Considering Dynamic Time Series Characteristics under Uncertainty Mar 31, 2023 - Mar 30, 2026
ICU patients with sepsis have rapidly changing conditions and high mortality. Because of it, early prediction and timely intervention are the keys to reducing the risk of death.
The project aims to provide critical care physicians with an intellige...
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REMEDI4ALL BUILDING A SUSTAINABLE EUROPEAN INNOVATION PLATFORM TO ENHANCE THE REPURPOSING OF MEDICINES FOR ALL Sep 1, 2022 - Aug 31, 2027
Osteogenesis imperfecta (OI) causes skeletal fragility, bone pain, sarcopenia and reduced connective tissue resilience, shown as hypermobility and aortic root dilatation (in adults). There is no effective treatment for OI. Current agents only target...
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Evaluating the effectiveness and acceptability of free door to door transport to increase the uptake of breast screening appointments in Yorkshire: A cluster randomised GP pilot trial Jun 1, 2023 - Jul 31, 2025
Breast screening is one of the key tools in identifying breast cancer at an early stage. It is currently offered to women between the ages of 50 and 70 on a three yearly cycle. Whilst nationally breast screening uptake is 70% this leaves 30% of wom...
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NIHR Pre-doctoral Fellowship - Laura Hermann Sep 1, 2021 - Aug 31, 2023
Pre-doctoral fellowship application for Laura Hermann
A phase II, randomised feasibility trial of a tailored, home-based exercise programme on disease-free survival among early stage high-risk recurring cancers in Yorkshire Sep 1, 2022 - Aug 31, 2026
To determine the effect exercise has on preventing secondary cancers and improving 5-year survival rates among people diagnosed with breast, bowel, lung, or prostate cancers in Yorkshire.
The Cognitive Daisy (COG-D) for improving care for residents with dementia in care homes: A feasibility RCT Apr 1, 2022 - Mar 31, 2024
Use of Cognitive Daisy in care homes
Lead: Petra Pollux, University of Lincoln
The TRANSPIRE Study: A prospective observational study to explore the relationship between nuTRition, protein intake ANd muScle mass loss during and after Pediatric Intensive caRE Aug 1, 2021 - Jul 31, 2023
Around 20 000 children are admitted to PICU each year in the UK and Ireland and around 13,000 of these stay more than 3 days in intensive care, with some children staying a lot longer. As children’s intensive care in the UK has improved in the last d...
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Adapting a smartphone-based rehabilitation programme for older adults living with and beyond cancer: an intervention development study Apr 1, 2022 - Apr 30, 2024
The number of people living with and beyond cancer is growing; many are over 65 years old who often have different and more complicated healthcare needs than younger people.
Being active is one of the best things people with, or who have had, canc...
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Pre-Operative Oncotype DX testing: A decision impact study (PRE-DX study) Jul 1, 2022 - Dec 31, 2024
Collaboration with Henry Cain, Newcastle on Tyne NHS Foundation Trust.
Newcastle will be research governance sponsor
Industry funded, investigator led study - to be funded by Exact Sciences
Endoscopic vein harvesting - Research Support Funding Aug 1, 2022 - Jul 31, 2023
The long saphenous vein remains the most frequently used conduit for coronary artery bypass grafting. Traditionally, the harvesting of this conduit has been by open incision extending upwards from the ankle in the inner side of the leg up to the groi...
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PUMA: Paediatric early warning system (PEWS): Utilisation and Mortality Avoidance. A prospective, mixed methods, before and after study identifying the evidence base for the core components of an effective PEWS and the development of an implementation package for implementation and use in the UK Oct 1, 2017 - Oct 31, 2018
In 2011 a research study compared the child health outcomes and death rate in the UK with other European countries. It was worrying that UK measures of child health were amongst the worst in Europe. It is not clear why that is and further work needs...
Read More about PUMA: Paediatric early warning system (PEWS): Utilisation and Mortality Avoidance. A prospective, mixed methods, before and after study identifying the evidence base for the core components of an effective PEWS and the development of an implementation package for implementation and use in the UK.