Dr Stefano Caserta
| Research Interests | As an academic, I have research interests in the areas of infection and tumour immunology, inflammation and ageing. My Immunology Lab at Hull York Medical School (University of Hull Campus) is particularly interested on how infection complicates chronic conditions, within a multimorbidity context. On the other hand, we are also interested in understanding how chronic conditions predispose to infection. For instance, we have active research looking at how pathogens breach/compromise the barrier function of the immune system in patients with diabetic foot ulcers. Other research in my lab is dissecting microbial interactions in cancer (particularly leukemia), with an emphasis on immunological function and tumour-cell behaviour. When pathogens spread beyond the original site of infection (for example, a skin ulcer/wound), they can give rise to a severe systemic illness, known as sepsis. This is a condition currently killing more people than the top three cancers (lung, breast and prostate) combined, in the US/Europe. So additionally, my lab is interested in understanding if specific conditions predispose for sepsis risk; how pathogens involved in sepsis hijack the immune system; and whether this can have an impact even after recovery. Molecular pathways of intercellular communication between immune cells relevant in infection, critical inflammatory conditions and ageing are currently under investigation in any of the above areas. |
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| Teaching and Learning | I am a Fellow of the Higher Education Academy. I take part in teaching and assessment activities in the Biomedical Science Subject Group at the University of Hull. My teaching interests mostly include Immunology and Cellular and Molecular Biology. I take part in lectures, tutorials and one-to-one teaching activities. I supervised a number of students in the lab in my past career, including many successful researchers and scientists who are now progressing well in their career. If you are a recent biomedical/biological science / infection and immunity / medicine graduate and would like to join my lab to study any of the above areas, either as a Master or PhD/MD student, please do get in contact: stefano.caserta@hyms.ac.uk |
| Scopus Author ID | 24074363000 |
| PhD Supervision Availability | Yes |
| PhD Topics | Infection and Immunity T cell biology Cancer Immunology |