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Matrix Metalloproteinase Activated Multimodal 'Theranostic' Drug Delivery Imaging Agents For Thrombosis

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PEGylation of indium phosphide quantum dots prevents quantum dot mediated platelet activation (2024)
Journal Article
Naylor-Adamson, L., Price, T. W., Booth, Z., Leonard, S. V. L., Gallo, J., Tung, L. D., Harvell-Smith, S., Thi Kim Thanh, N., Aslam, Z., Allsup, D., Hondow, N., Chamberlain, T., Schneider, J. E., Naseem, K., Bouillard, J. S. G., Stasiuk, G. J., & Calaminus, S. D. (in press). PEGylation of indium phosphide quantum dots prevents quantum dot mediated platelet activation. Journal of Materials Chemistry B, https://doi.org/10.1039/d4tb01334d

Quantum dots (QDs) are semiconducting inorganic nanocrystals, that have garnered interest in biological and medical spheres due, to their potential benefits in biomedical imaging and drug-delivery systems. Indium phosphide QDs shelled with zinc sulph... Read More about PEGylation of indium phosphide quantum dots prevents quantum dot mediated platelet activation.

Impact of Surface Ligand on the Biocompatibility of InP/ZnS Quantum Dots with Platelets (2023)
Journal Article
Gil, H. M., Booth, Z., Price, T. W., Lee, J., Naylor‐Adamson, L., Avery, M., Muravitskaya, A., Hondow, N., Allsup, D., Schneider, J. E., Naseem, K., Adawi, A. M., Bouillard, J. S. G., Chamberlain, T. W., Calaminus, S. D., & Stasiuk, G. J. (in press). Impact of Surface Ligand on the Biocompatibility of InP/ZnS Quantum Dots with Platelets. Small, Article 2304881. https://doi.org/10.1002/smll.202304881

InP/ZnS quantum dots (QDs) have received a large focus in recent years as a safer alternative to heavy metal-based QDs. Given their intrinsic fluorescent imaging capabilities, these QDs can be potentially relevant for in vivo platelet imaging. The In... Read More about Impact of Surface Ligand on the Biocompatibility of InP/ZnS Quantum Dots with Platelets.

NIR-quantum dots in biomedical imaging and their future (2021)
Journal Article
Gil, H. M., Price, T. W., Chelani, K., Bouillard, J. S. G., Calaminus, S. D., & Stasiuk, G. J. (2021). NIR-quantum dots in biomedical imaging and their future. iScience, 24(3), Article 102189. https://doi.org/10.1016/j.isci.2021.102189

Fluorescence imaging has gathered interest over the recent years for its real-time response and high sensitivity. Developing probes for this modality has proven to be a challenge. Quantum dots (QDs) are colloidal nanoparticles that possess unique opt... Read More about NIR-quantum dots in biomedical imaging and their future.