Skip to main content

Research Repository

Advanced Search

Matrix Metalloproteinase Activated Multimodal 'Theranostic' Drug Delivery Imaging Agents For Thrombosis

People Involved

Scandium calix[n]arenes (n= 4, 6, 8): structural, cytotoxicity and ring opening polymerization studies (2021)
Journal Article
Alshamrani, A. F., Santoro, O., Prior, T. J., Alamri, M. A., Stasiuk, G. J., Elsegood, M. R. J., & Redshaw, C. (2021). Scandium calix[n]arenes (n= 4, 6, 8): structural, cytotoxicity and ring opening polymerization studies. Dalton Transactions : an international journal of inorganic chemistry, 50(24), 8302-8306. https://doi.org/10.1039/d1dt01330k

Interaction of [Sc(OR)3] (R = iPr or triflate) with p-tert-butylcalix[n]arenes, where n = 4, 6, or 8, affords a number of intriguing structural motifs, which are relatively non-toxic (cytotoxicity evaluated against cell lines HCT116 and HT-29) and a... Read More about Scandium calix[n]arenes (n= 4, 6, 8): structural, cytotoxicity and ring opening polymerization studies.

A Single-Pot Template Reaction Towards a Manganese-Based T1 Contrast Agent (2021)
Journal Article
Stasiuk, G. J., Martins, A. F., Botta, M., Prior, T. J., Price, T. W., Kenning, L., Carniato, F., Hoffmann, S. H. L., & Anbu, S. (in press). A Single-Pot Template Reaction Towards a Manganese-Based T1 Contrast Agent. Angewandte Chemie, 60(19), 10736-10744. https://doi.org/10.1002/anie.202100885

Manganese-based contrast agents (MnCAs) have emerged as suitable alternatives to gadolinium-based contrast agents (GdCAs). However, due to their kinetic lability and laborious synthetic procedures, only a few MnCAs have found clinical MRI application... Read More about A Single-Pot Template Reaction Towards a Manganese-Based T1 Contrast Agent.