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Endolysin technology for selective management of MRSA biofilms on skin and wounds

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Dr Holly Wilkinson H.N.Wilkinson@hull.ac.uk
Senior Lecturer - Wound Healing and Microbiome

Selective Depletion of Staphylococcus aureus Restores the Skin Microbiome and Accelerates Tissue Repair after Injury (2024)
Journal Article
Wilkinson, H. N., Stafford, A. R., Rudden, M., Rocha, N. D., Kidd, A. S., Iveson, S., Bell, A. L., Hart, J., Duarte, A., Frieling, J., Janssen, F., Röhrig, C., de Rooij, B., Ekhart, P. F., & Hardman, M. J. (2024). Selective Depletion of Staphylococcus aureus Restores the Skin Microbiome and Accelerates Tissue Repair after Injury. Journal of Investigative Dermatology, 144(8), 1865-1876. https://doi.org/10.1016/j.jid.2024.01.018

Our skin is home to a diverse community of commensal microorganisms integral to cutaneous function. However, microbial dysbiosis and barrier perturbation increase the risk of local and systemic infection. Staphylococcus aureus is a particularly probl... Read More about Selective Depletion of Staphylococcus aureus Restores the Skin Microbiome and Accelerates Tissue Repair after Injury.