Developing a human skin infection model to replace rodent studies and explore host-microbe interactions

Dr Holly Wilkinson H.N.Wilkinson@hull.ac.uk
Lecturer in Wound Healing

Professor Matthew Hardman M.Hardman@hull.ac.uk
Chair in Wound Healing / HYMS Director of Research

Dr Michelle Rudden

The role of bacteria in the skin: Cold atmospheric plasma for the treatment of pathological skin healing Apr 1, 2017 - Mar 31, 2020
Chronic wounds remain a major area of unmet clinical need, with infection a principle contributing factor to wound chronicity. This project builds upon strong preliminary data suggesting that healing outcome can be directly linked to both wound micro... Read More about The role of bacteria in the skin: Cold atmospheric plasma for the treatment of pathological skin healing.

MICA: The role of arginase in chronic delayed wound healing Aug 1, 2016 - Oct 17, 2017

Development and application of a new technology for the targeted management of biofilms in human chronic wounds Nov 1, 2018 - Oct 31, 2019

Development of an immune-responsive 3D skin model May 1, 2019 - Jul 31, 2019
The immune system is an essential regulator of normal physiologic and wound repair processes within the skin, and it contributes to the progression of many different skin diseases. The nature of the interactions between circulating immune cells and r... Read More about Development of an immune-responsive 3D skin model.

Development of fully humanised ex vivo human skin wound and infection model Jul 1, 2019 - Sep 2, 2019
Summer Studentship Project 2019