Outputs (23)

The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing (2024)
Journal Article
Nickolay, T., Ingle, L., Hoye, A., Garrett, A. T., & Gleadall-Siddall, D. O. (2025). The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing. Science & Sports, 40(3), 239-247. https://doi.org/10.1016/j.scispo.2024.10.003

Objectives: This study aimed to assess the relative and absolute reliability (agreement) of various parameters derived from the oxygen pulse ( O˙2Pulse) curve during cardiopulmonary exercise testing (CPET), a tool critical for evaluating cardiopulmon... Read More about The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing.

Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology (2024)
Journal Article
Nickolay, T., McGregor, G., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., Banerjee, P., Shave, R., Metcalfe, J., Hoye, A., & Ingle, L. (2024). Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology. PLoS ONE, 19(3 March), Article e0299486. https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology.

The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease (2024)
Thesis
Nickolay, T. The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4659878

This thesis investigates the utility of cardiopulmonary exercise testing (CPET) in assessing and managing patients with coronary artery disease (CAD), particularly focusing on the significance of oxygen pulse (O2Pulse) inflections as a marker for myo... Read More about The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease.

Assessment of frailty and quality of life in octogenarians with symptomatic coronary artery disease : the FRAIL HEART study (2020)
Thesis
Qayyum, S. Assessment of frailty and quality of life in octogenarians with symptomatic coronary artery disease : the FRAIL HEART study. (Thesis). Hull York Medical School, the University of Hull and the University of York. https://hull-repository.worktribe.com/output/4223376

BACKGROUND:
Symptomatic coronary artery disease (CAD) is an increasing problem for older adults, however little is known about the relationship between frailty and health outcomes.
PURPOSE:
To determine the prevalence of, and relationship between... Read More about Assessment of frailty and quality of life in octogenarians with symptomatic coronary artery disease : the FRAIL HEART study.

Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence (2019)
Journal Article
Nickolay, T., Nichols, S., Ingle, L., & Hoye, A. (2020). Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence. Current Cardiology Reviews, 16(3), 212-220. https://doi.org/10.2174/1573403X15666190819144336

Coronary collateral vessels supply blood to areas of myocardium at risk after arterial occlusion. Flow through these channels is driven by a pressure gradient between the donor and the occluded artery. Concomitant with increased collateral flow is an... Read More about Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence.

Multi-disciplinary palliative care is effective in people with symptomatic heart failure: A systematic review and narrative synthesis (2019)
Journal Article
Datla, S., Verberkt, C. A., Hoye, A., Janssen, D. J. A., & Johnson, M. J. (2019). Multi-disciplinary palliative care is effective in people with symptomatic heart failure: A systematic review and narrative synthesis. Palliative medicine, 33(8), 1003-1016. https://doi.org/10.1177/0269216319859148

Background: Despite recommendations, people with heart failure have poor access to palliative care. Aim: To identify the evidence in relation to palliative care for people with symptomatic heart failure. Design: Systematic review and narrative synthe... Read More about Multi-disciplinary palliative care is effective in people with symptomatic heart failure: A systematic review and narrative synthesis.

Acute coronary syndromes, platelets and the endothelium (2019)
Thesis
Rossington, J. A. Acute coronary syndromes, platelets and the endothelium. (Thesis). Hull York Medical School, the University of Hull and the University of York. https://hull-repository.worktribe.com/output/4222365

ABSTRACT
Background: Acute coronary syndromes (ACS) are medical emergencies. Platelet and endothelial function are fundamental to the pathophysiology; and implicated in secondary conditions such as no reflow (NR). Guidelines support the administrati... Read More about Acute coronary syndromes, platelets and the endothelium.

Safety and efficacy of a sirolimus-eluting coronary stent with ultra-thin strut for treatment of atherosclerotic lesions (TALENT): a prospective multicentre randomised controlled trial (2019)
Journal Article
Zaman, A., de Winter, R. J., Kogame, N., Chang, C. C., Modolo, R., Spitzer, E., Tonino, P., Hofma, S., Zurakowski, A., Smits, P. C., Prokopczuk, J., Moreno, R., Choudhury, A., Petrov, I., Cequier, A., Kukreja, N., Hoye, A., Iniguez, A., Ungi, I., Serra, A., …Serruys, P. W. (2019). Safety and efficacy of a sirolimus-eluting coronary stent with ultra-thin strut for treatment of atherosclerotic lesions (TALENT): a prospective multicentre randomised controlled trial. Lancet, 393(10175), 987-997. https://doi.org/10.1016/S0140-6736%2818%2932467-X

Background: Supraflex is a sirolimus-eluting stent with a biodegradable polymer coating and ultra-thin struts. We aimed to compare Supraflex with the standard of care, Xience, an everolimus-eluting stent with a durable polymer coating, regarding clin... Read More about Safety and efficacy of a sirolimus-eluting coronary stent with ultra-thin strut for treatment of atherosclerotic lesions (TALENT): a prospective multicentre randomised controlled trial.

Cardiogoniometry compared to fractional flow reserve at identifying physiologically significant coronary stenosis: The Cardioflow Study (2018)
Journal Article
Brown, O. I., Clark, A. L., Chelliah, R., Davison, B. J., Mather, A. N., Cunnington, M. S., John, J., Alahmar, A., Oliver, R., Aznaouridis, K., & Hoye, A. (2018). Cardiogoniometry compared to fractional flow reserve at identifying physiologically significant coronary stenosis: The Cardioflow Study. Cardiovascular Engineering and Technology, 9(3), 439-446. https://doi.org/10.1007/s13239-018-0354-1

Cardiogoniometry (CGM) is method of 3-dimensional electrocardiographic assessment which has been shown to identify patients with angiographically defined, stable coronary artery disease (CAD). However, angiographic evidence of CAD, does not always co... Read More about Cardiogoniometry compared to fractional flow reserve at identifying physiologically significant coronary stenosis: The Cardioflow Study.

The HF-CGM study: An analysis of cardiogoniometric axes in patients with cardiac resynchronization therapy (2017)
Journal Article
Clark, A. L., Hoye, A., Beddoes, G., Nikolaidou, T., & Brown, O. I. (2018). The HF-CGM study: An analysis of cardiogoniometric axes in patients with cardiac resynchronization therapy. IEEE transactions on bio-medical engineering / Bio-medical Engineering Group, 65(8), 1711-1716. https://doi.org/10.1109/TBME.2017.2769060

Goal: The HF-CGM is a proof-of-principle study to investigate whether cardiogoniometry (CGM), a three-dimensional electrocardiographic method, can differentiate between pacing modes in patients with cardiac resynchronization therapy (CRT). Methods: A... Read More about The HF-CGM study: An analysis of cardiogoniometric axes in patients with cardiac resynchronization therapy.