Outputs (41)

Authors' reply: Expanding horizons in metastatic prostate cancer treatment (2011)
Journal Article
Sturge, J., Caley, M. P., & Waxman, J. (2011). Authors' reply: Expanding horizons in metastatic prostate cancer treatment. Nature Reviews Clinical Oncology, 8(10), 625. https://doi.org/10.1038/nrclinonc.2011.67-c2

Bone metastasis in prostate cancer: Emerging therapeutic strategies (2011)
Journal Article
Sturge, J., Caley, M. P., & Waxman, J. (2011). Bone metastasis in prostate cancer: Emerging therapeutic strategies. Nature Reviews Clinical Oncology, 8(6), 357-368. https://doi.org/10.1038/nrclinonc.2011.67

Metastatic bone disease (MBD) in advanced-stage cancer increases the risk of intractable bone pain, pathological skeletal fracture, spinal-cord compression and decreased survival. The disease manifestation course during MBD is largely driven by homot... Read More about Bone metastasis in prostate cancer: Emerging therapeutic strategies.

Sphingosine kinase-1 and the collagen-binding receptor Endo180 cooperate to mediate collagen remodelling by stromal fibroblasts (2010)
Presentation / Conference Contribution
Bruche, S., Caley, M., Pshezhetskiy, D., & Sturge, J. (2010, December). Sphingosine kinase-1 and the collagen-binding receptor Endo180 cooperate to mediate collagen remodelling by stromal fibroblasts

Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation (2010)
Presentation / Conference Contribution
Nunes, J., Sauer, L., Turner, J., Waxman, J., Sturge, J., & Pshezhetskiy, D. Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation

Biological and clinical implications of nicastrin expression in invasive breast cancer (2010)
Journal Article
Filipović, A., Gronau, J. H., Green, A. R., Wang, J., Vallath, S., Shao, D., Rasul, S., Ellis, I. O., Yagüe, E., Sturge, J., & Coombes, R. C. (2011). Biological and clinical implications of nicastrin expression in invasive breast cancer. Breast cancer research and treatment, 125(1), 43-53. https://doi.org/10.1007/s10549-010-0823-1

Nicastrin is an essential component of the gamma secretase (GS) enzyme complex, required for its synthesis and recognition of substrates for proteolytic cleavage. The purpose of this study was to investigate whether nicastrin has prognostic value or... Read More about Biological and clinical implications of nicastrin expression in invasive breast cancer.

Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions (2009)
Presentation / Conference Contribution
Sturge, J. (2009, May). Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions. Presented at BIT‘s 2nd Annual World Cancer Congess 2009, Beijing

A major clinical complication in patients with advanced prostate cancer is metastasis to bone where osteoblastic and/or osteoclastic activity results in a highly destructive tissue remodelling process.Recent in vivo studies have identified important... Read More about Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions.

Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression (2008)
Journal Article
Kogianni, G., Walker, M. M., Waxman, J., & Sturge, J. (2009). Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression. European Journal of Cancer, 45(4), 685-693. https://doi.org/10.1016/j.ejca.2008.11.023

Endo180 (CD280; MRC2; uPARAP) regulates collagen remodelling and chemotactic cell migration through cooperation with membrane type-1 matrix metalloproteinase (MT1-MMP), urokinase-type plasminogen activator receptor (uPAR) and urokinase-type plasminog... Read More about Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression.

The role of endo180 in the development of metastatic prostate cancer bone lesions (2008)
Presentation / Conference Contribution
Kogianni, G., Elefteriou, K., Waxman, . J., Cobb, . J. P., & Sturge, J. (2008, October). The role of endo180 in the development of metastatic prostate cancer bone lesions. Presented at International Conference of Anticancer Research 2008, Kos, Greece

Endo180 expression by tumour cells with an invasive phenotype correlates with prostate cancer progression (2008)
Presentation / Conference Contribution
Kogianni, G., Walker, M., Waxman, J., & Sturge, J. Endo180 expression by tumour cells with an invasive phenotype correlates with prostate cancer progression

OC6. Endo180 function in metastatic prostate cancer bone lesions (2008)
Presentation / Conference Contribution
Kogianni, G., Eleftheriou, K., Waxman, J., Cobb, J. P., & Sturge, J. OC6. Endo180 function in metastatic prostate cancer bone lesions. Presented at VII International Conference on Cancer Induced Bone Disease, Edinburgh