Outputs (1121)

N-WASP activation by a β1-integrin-dependent mechanism supports PI3K-independent chemotaxis stimulated by urokinase-type plasminogen activator (2002)
Journal Article
Sturge, J., Hamelin, J., & Jones, G. (2002). N-WASP activation by a β1-integrin-dependent mechanism supports PI3K-independent chemotaxis stimulated by urokinase-type plasminogen activator. Journal of cell science, 115(4), 699-711

Urokinase-type plasminogen activator (uPA)-uPA receptor (uPAR) and epidermal growth factor (EGF)-EGF receptor (EGFR) expression is highly correlated with breast cancer metastasis. Phosphoinositide 3-kinase (PI3K), small Rho GTPases, such as Cdc42 and... Read More about N-WASP activation by a β1-integrin-dependent mechanism supports PI3K-independent chemotaxis stimulated by urokinase-type plasminogen activator.

Hyperbaric oxygen restores the antioxidant defence mechansim following exercise in patients with intermittent claudication (2001)
Presentation / Conference Contribution
Abidia, A., Kuhan, G., Laden, G., Bahia, H., Chetter, I., Greenman, J., & McCollum, P. Hyperbaric oxygen restores the antioxidant defence mechansim following exercise in patients with intermittent claudication

BACKGROUND: Intermittent claudication represents a minor ischaemia reperfusion episode. Exposure to hyperbaric oxygen during such episodes is a concern to many vascular surgeons because of the theoretical risk of generating excess free radicals. We a... Read More about Hyperbaric oxygen restores the antioxidant defence mechansim following exercise in patients with intermittent claudication.

Differential and cell-specific expression of calcitonin receptor-like receptor and receptor activity modifying proteins in the humans uterus (2001)
Journal Article
Nikitenko, L. L., Brown, N. S., Smith, D. M., MacKenzie, I. Z., Bicknell, R., & Rees, M. C. (2001). Differential and cell-specific expression of calcitonin receptor-like receptor and receptor activity modifying proteins in the humans uterus. Molecular Human Reproduction, 7(7), 655-664. https://doi.org/10.1093/molehr/7.7.655

The calcitonin receptor-like receptor (CRLR) can function as a receptor for either calcitonin gene-related peptide (CGRP) or adrenomedullin (AM), depending upon co-expression with members of a novel family of receptor activity-modifying proteins (RAM... Read More about Differential and cell-specific expression of calcitonin receptor-like receptor and receptor activity modifying proteins in the humans uterus.

Fibrin monomer and fibrinopeptide B act additively to increase DNA synthesis in smooth muscle cells cultured from human saphenous vein (2001)
Journal Article
Sturge, J., Carey, N., Davies, A. H., & Powell, J. T. (2001). Fibrin monomer and fibrinopeptide B act additively to increase DNA synthesis in smooth muscle cells cultured from human saphenous vein. Journal of vascular surgery, 33(4), 847-853. https://doi.org/10.1067/mva.2001.111984

Purpose: We investigated the hypothesis that fibrinogen increased DNA synthesis (and cell proliferation) of smooth muscle cells (SMCs) cultured from human saphenous vein and that the increased DNA synthesis was attenuated when cells were cultured on... Read More about Fibrin monomer and fibrinopeptide B act additively to increase DNA synthesis in smooth muscle cells cultured from human saphenous vein.

Adrenomedullin is an autocrine regulator of endothelial growth in human endometrium (2000)
Journal Article
Nikitenko, L. L., MacKenzie, I. Z., Rees, M. C., & Bicknell, R. (2000). Adrenomedullin is an autocrine regulator of endothelial growth in human endometrium. Molecular Human Reproduction, 6(9), 811-819. https://doi.org/10.1093/molehr/6.9.811

Human endometrium is a mucosa served by a microvascular blood supply that involves benign angiogenesis under the control of ovarian steroids throughout reproductive life. Adrenomedullin is a multifunctional 52-amino acid peptide involved in numerous... Read More about Adrenomedullin is an autocrine regulator of endothelial growth in human endometrium.

Localisation by in situ hybridisation of S100A4 (p9Ka) mRNA in primary human breast tumour specimens (2000)
Journal Article
Nikitenko, L. L., Lloyd, B. H., Rudland, P. S., Fear, S., & Barraclough, R. (2000). Localisation by in situ hybridisation of S100A4 (p9Ka) mRNA in primary human breast tumour specimens. International journal of cancer. Journal international du cancer, 86(2), 219-228. https://doi.org/10.1002/%28SICI%291097-0215%2820000415%2986%3A2%3C219%3A%3AAID-IJC11%3E3.0.CO%3B2-7

Rodent S 100A4 (p9Ka) induces a metastatic phenotype in benign rat mammary tumour cells and cooperates with the neu oncogene to produce metastatic tumours in a transgenic mouse model system. Human S 100A4 possesses similar metastasis-inducing propert... Read More about Localisation by in situ hybridisation of S100A4 (p9Ka) mRNA in primary human breast tumour specimens.

Regulation by fibrinogen and its products of intercellular adhesion molecule-1 expression in human saphenous vein endothelial cells (2000)
Journal Article
Harley, S. L., Sturge, J., & Powell, J. T. (2000). Regulation by fibrinogen and its products of intercellular adhesion molecule-1 expression in human saphenous vein endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 20(3), 652-658. https://doi.org/10.1161/01.ATV.20.3.652

It has been reported that fibrinogen may act as a bridging ligand, binding to intercellular adhesion molecule-1 (ICAM-1) on human umbilical vein endothelial cells and to Mac-1 on THP-1 cells (a monocytic cell line) to increase adhesion. In this study... Read More about Regulation by fibrinogen and its products of intercellular adhesion molecule-1 expression in human saphenous vein endothelial cells.

Detection and differentiation on pathogenic Acanthamoeba (1999)
Thesis
Khan, N. A. Detection and differentiation on pathogenic Acanthamoeba. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4217566

Acanthamoeba are free-living and opportunistic protozoa that are ubiquitous in nature. Human infection due to Acanthamoeba can involve the brain, skin, lung and eyes. However, eye infection, Acanthamoeba keratitis, is the most common infection. Acant... Read More about Detection and differentiation on pathogenic Acanthamoeba.

Immunocytochemical and in situ hybridization studies of the distribution of calbindin D(9k) in the bovine placenta throughout pregnancy (1998)
Journal Article
Nikitenko, L., Morgan, G., Kolesnikov, S. I., & Wooding, F. B. (1998). Immunocytochemical and in situ hybridization studies of the distribution of calbindin D(9k) in the bovine placenta throughout pregnancy. Journal of Histochemistry and Cytochemistry, 46(5), 679-688. https://doi.org/10.1177/002215549804600513

The fetus must transport considerable and increasing amounts of calcium across the placental trophoblast epithelium to support growth and development and bone formation. Active calcium transport across epithelia has been shown to correlate with calbi... Read More about Immunocytochemical and in situ hybridization studies of the distribution of calbindin D(9k) in the bovine placenta throughout pregnancy.

Calbindin-D(9κ) protein and mRNA localisation in bovine placenta (1997)
Presentation / Conference Contribution
Nikitenko, L., Morgan, G., & Wooding, F. B. Calbindin-D(9κ) protein and mRNA localisation in bovine placenta. Presented at Annual General Meeting of the Anatomical Society of Great Britain and Ireland, 17-19 Dec 1996, St George’s Hospital Medical School, University of London