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Sensitivity to model geometry in finite element analyses of reconstructed skeletal structures: Experience with a juvenile pelvis (2014)
Journal Article
Watson, P. J., Fagan, M. J., & Dobson, C. A. (2015). Sensitivity to model geometry in finite element analyses of reconstructed skeletal structures: Experience with a juvenile pelvis. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 229(1), 9-19. https://doi.org/10.1177/0954411914564476

Biomechanical analysis of juvenile pelvic growth can be used in the evaluation of medical devices and investigation of hip joint disorders. This requires access to scan data of healthy juveniles, which are not always freely available. This article an... Read More about Sensitivity to model geometry in finite element analyses of reconstructed skeletal structures: Experience with a juvenile pelvis.

Investigating the efficacy of bisphosphonates treatment against multiple myeloma induced bone disease using a computational model (2014)
Presentation / Conference Contribution
Ji, B., Yang, Q., Genever, P. G., & Fagan, M. J. Investigating the efficacy of bisphosphonates treatment against multiple myeloma induced bone disease using a computational model

Multiple myeloma (MM)-induced bone disease is mortal for most MM patients. Bisphosphonates are first-line treatment for MM-induced bone disease, since it can inhibit osteoclast activity and the resultant bone resorption by suppressing the differentia... Read More about Investigating the efficacy of bisphosphonates treatment against multiple myeloma induced bone disease using a computational model.

Non-invasive estimation of left atrial dominant frequency in atrial fibrillation from different electrode sites: Insight from body surface potential mapping (2014)
Journal Article
Bojarnejad, M., Blake, J. R., Bourke, J., Shepherd, E., Murray, A., & Langley, P. (2014). Non-invasive estimation of left atrial dominant frequency in atrial fibrillation from different electrode sites: Insight from body surface potential mapping. Journal of atrial fibrillation, 7(3), 6-10

© 2014, CardioFront LLC. All rights reserved. The dominant driving sources of atrial fibrillation are often found in the left atrium, but the expression of left atrial activation on the body surface is poorly understood. Using body surface potential... Read More about Non-invasive estimation of left atrial dominant frequency in atrial fibrillation from different electrode sites: Insight from body surface potential mapping.

Recurring patterns of atrial fibrillation in surface ECG predict restoration of sinus rhythm by catheter ablation (2014)
Journal Article
Di Marco, L. Y., Raine, D., Bourke, J. P., & Langley, P. (2014). Recurring patterns of atrial fibrillation in surface ECG predict restoration of sinus rhythm by catheter ablation. Computers in biology and medicine, 54, 172-179. https://doi.org/10.1016/j.compbiomed.2014.09.005

Background Non-invasive tools to help identify patients likely to benefit from catheter ablation (CA) of atrial fibrillation (AF) would facilitate personalised treatment planning. Aim To investigate atrial waveform organisation through recurrence plo... Read More about Recurring patterns of atrial fibrillation in surface ECG predict restoration of sinus rhythm by catheter ablation.

Masticatory biomechanics in the rabbit: a multi-body dynamics analysis (2014)
Journal Article
Watson, P. J., Gröning, F., Curtis, N., Fitton, L. C., Herrel, A., McCormack, S. W., & Fagan, M. J. (2014). Masticatory biomechanics in the rabbit: a multi-body dynamics analysis. Journal of the Royal Society interface / the Royal Society, 11(99), Article 20140564. https://doi.org/10.1098/rsif.2014.0564

Multi-body dynamics is a powerful engineering tool which is becoming increasingly popular for the simulation and analysis of skull biomechanics. This paper presents the first application of multi-body dynamics to analyse the biomechanics of the rabbi... Read More about Masticatory biomechanics in the rabbit: a multi-body dynamics analysis.

Extracting fetal heart beats from maternal abdominal recordings: Selection of the optimal principal components (2014)
Journal Article
Di Maria, C., Liu, C., Zheng, D., Murray, A., & Langley, P. (2014). Extracting fetal heart beats from maternal abdominal recordings: Selection of the optimal principal components. Physiological Measurement, 35(8), 1649-1664. https://doi.org/10.1088/0967-3334/35/8/1649

This study presents a systematic comparison of different approaches to the automated selection of the principal components (PC) which optimise the detection of maternal and fetal heart beats from non-invasive maternal abdominal recordings. A public d... Read More about Extracting fetal heart beats from maternal abdominal recordings: Selection of the optimal principal components.

The biomechanical function of periodontal ligament fibres in orthodontic tooth movement (2014)
Journal Article
McCormack, S. W., Witzel, U., Watson, P. J., Fagan, M. J., & Gröning, F. (2014). The biomechanical function of periodontal ligament fibres in orthodontic tooth movement. PLoS ONE, 9(7), e102387. https://doi.org/10.1371/journal.pone.0102387

Orthodontic tooth movement occurs as a result of resorption and formation of the alveolar bone due to an applied load, but the stimulus responsible for triggering orthodontic tooth movement remains the subject of debate. It has been suggested that th... Read More about The biomechanical function of periodontal ligament fibres in orthodontic tooth movement.

Recurring patterns in stationary intervals of abdominal uterine electromyograms during gestation (2014)
Journal Article
Di Marco, L. Y., Di Maria, C., Tong, W.-C., Taggart, M. J., Robson, S. C., & Langley, P. (2014). Recurring patterns in stationary intervals of abdominal uterine electromyograms during gestation. Medical and Biological Engineering and Computing, 52(8), 707-716. https://doi.org/10.1007/s11517-014-1174-6

Abdominal uterine electromyograms (uEMG) studies have focused on uterine contractions to describe the evolution of uterine activity and preterm birth (PTB) prediction. Stationary, non-contracting uEMG has not been studied. The aim of the study was to... Read More about Recurring patterns in stationary intervals of abdominal uterine electromyograms during gestation.

In vivo cranial bone strain and bite force in the agamid lizard Uromastyx geyri (2014)
Journal Article
Porro, L. B., Ross, C. F., Iriarte-Diaz, J., O'Reilly, J. C., Evans, S. E., & Fagan, M. J. (2014). In vivo cranial bone strain and bite force in the agamid lizard Uromastyx geyri. The journal of experimental biology, 217(11), 1983-1992. https://doi.org/10.1242/jeb.096362

In vivo bone strain data are the most direct evidence of deformation and strain regimes in the vertebrate cranium during feeding and can provide important insights into skull morphology. Strain data have been collected during feeding across a wide ra... Read More about In vivo cranial bone strain and bite force in the agamid lizard Uromastyx geyri.

Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease (2014)
Journal Article
Ji, B., Genever, P. G., Patton, R. J., & Fagan, M. J. (2014). Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease. International journal for numerical methods in biomedical engineering, 30(11), 1085-1102. https://doi.org/10.1002/cnm.2645

Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM-in... Read More about Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease.