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Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review (2017)
Journal Article
Totty, J., Bua, N., Smith, G., Harwood, A., Carradice, D., Wallace, T., & Chetter, I. (2017). Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review. Journal of Wound Care, 26(3), 107-114. https://doi.org/10.12968/jowc.2017.26.3.107

Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed. They are a recent addition to the wound care profe... Read More about Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review.

TRPV1 polymorphisms influence capsaicin cough sensitivity in men (2017)
Journal Article
Sadofsky, L. R., Cantero-Recasens, G., Wright, C., Valverde, M. A., & Morice, A. H. (2017). TRPV1 polymorphisms influence capsaicin cough sensitivity in men. Journal of thoracic disease, 9(3), 839-840. https://doi.org/10.21037/jtd.2017.03.50

Capsaicin, the hot component of chilli peppers, is a well-known tussive agent, which is regularly used as a tool to study cough and antitussives (1). Capsaicin is known to activate the transient receptor potential vanilloid 1 (TRPV1) cation channel w... Read More about TRPV1 polymorphisms influence capsaicin cough sensitivity in men.

Tussive challenge with ATP and AMP: does it reveal cough hypersensitivity? (2017)
Journal Article
Fowles, H. E., Rowland, T., Wright, C., & Morice, A. (2017). Tussive challenge with ATP and AMP: does it reveal cough hypersensitivity?. European respiratory journal, 49(2), Article ARTN 1601452. https://doi.org/10.1183/13993003.01452-2016

Recent studies have demonstrated that blockade of P2X3 adenosine triphosphate (ATP) receptors may profoundly inhibit chronic cough. We have considered whether inhaled ATP produces a tussive response and whether chronic cough patients are hypersensiti... Read More about Tussive challenge with ATP and AMP: does it reveal cough hypersensitivity?.

The differential effects of systemic vasoconstrictors on human pulmonary artery tension (2017)
Journal Article
Hussain, A., Bennett, R., Haqzad, Y., Qadri, S., Chaudhry, M., Cowen, M., Loubani, M., & Morice, A. (2017). The differential effects of systemic vasoconstrictors on human pulmonary artery tension. European Journal of Cardio-Thoracic Surgery, 51(5), 880-886. https://doi.org/10.1093/ejcts/ezw410

© The Author 2017. Published by Oxford University Press. All rights reserved. Objectives: Acute pulmonary hypertension following cardiac surgery can have a significant effect on postoperative morbidity and mortality. However, limited data are availab... Read More about The differential effects of systemic vasoconstrictors on human pulmonary artery tension.

Exploring the relation between changes in NT-proBNP and renal function in patients with suspected heart failure using structural equation modelling (2017)
Journal Article
Zhang, J., Wong, K., Clark, A. L., & Cleland, J. G. (2017). Exploring the relation between changes in NT-proBNP and renal function in patients with suspected heart failure using structural equation modelling. International journal of cardiology, 233, 67-72. https://doi.org/10.1016/j.ijcard.2017.01.127

Background The relation between changes in NT-proBNP and renal function has commonly been studied using multiple regressions, which may ignore the complexity of relations between related variables. Methods and results Data were collected from patient... Read More about Exploring the relation between changes in NT-proBNP and renal function in patients with suspected heart failure using structural equation modelling.

Hypoxic pulmonary vasoconstriction in humans: Tale or myth (2017)
Journal Article
Hussain, A., Suleiman, M. S., George, S. J., Loubani, M., & Morice, A. (2017). Hypoxic pulmonary vasoconstriction in humans: Tale or myth. Open Cardiovascular Medicine Journal, 11, 1-13. https://doi.org/10.2174/1874192401711010001

© Hussain et al. Hypoxic Pulmonary vasoconstriction (HPV) describes the physiological adaptive process of lungs to preserves systemic oxygenation. It has clinical implications in the development of pulmonary hypertension which impacts on outcomes of... Read More about Hypoxic pulmonary vasoconstriction in humans: Tale or myth.

Diagnostic accuracy of fractional exhaled nitric oxide measurement in predicting cough-variant asthma and eosinophilic bronchitis in adults with chronic cough: A systematic review and meta-analysis (2017)
Journal Article
Song, W. J., Kim, H. J., Shim, J. S., Won, H. K., Kang, S. Y., Sohn, K. H., Kim, B. K., Jo, E. J., Kim, M. H., Kim, S. H., Park, H. W., Kim, S. S., Chang, Y. S., Morice, A. H., Lee, B. J., & Cho, S. H. (2017). Diagnostic accuracy of fractional exhaled nitric oxide measurement in predicting cough-variant asthma and eosinophilic bronchitis in adults with chronic cough: A systematic review and meta-analysis. Journal of Allergy and Clinical Immunology, 140(3), 701-709. https://doi.org/10.1016/j.jaci.2016.11.037

© 2017 American Academy of Allergy, Asthma & Immunology Background Individual studies have suggested the utility of fractional exhaled nitric oxide (FENO) measurement in detecting cough-variant asthma (CVA) and eosinophilic bronchitis (EB) in patie... Read More about Diagnostic accuracy of fractional exhaled nitric oxide measurement in predicting cough-variant asthma and eosinophilic bronchitis in adults with chronic cough: A systematic review and meta-analysis.

Rococo study: a real-world evaluation of an over-the-counter medicine in acute cough (a multicentre, randomised, controlled study) (2017)
Journal Article
Birring, S. S., Brew, J., Kilbourn, A., Edwards, V., Wilson, R., & Morice, A. H. (2017). Rococo study: a real-world evaluation of an over-the-counter medicine in acute cough (a multicentre, randomised, controlled study). BMJ open, 7(1), e014112. https://doi.org/10.1136/bmjopen-2016-014112

Objectives To investigate the efficacy and safety of CS1002, an over-the-counter cough treatment containing diphenhydramine, ammonium chloride and levomenthol in a cocoa-based demulcent.

Design A multicentre, randomised, parallel group, controlled... Read More about Rococo study: a real-world evaluation of an over-the-counter medicine in acute cough (a multicentre, randomised, controlled study).