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Outputs (82)

Patient-specific mental rehearsal with three-dimensional models before low anterior resection: randomized clinical trial (2020)
Journal Article
Yiasemidou, M., Mushtaq, F., Basheer, M., Galli, R., Panagiotou, D., Stock, S., Preston, N., Mon-Williams, M., Jayne, D. G., & Miskovic, D. (2021). Patient-specific mental rehearsal with three-dimensional models before low anterior resection: randomized clinical trial. BJS Open, 5(2), Article zraa004. https://doi.org/10.1093/bjsopen/zraa004

Background
It was hypothesized that preparing for a surgical procedure, taking into account individual patient characteristics, may facilitate the procedure and improve surgical quality. The aim of this study was to compare different case-specific,... Read More about Patient-specific mental rehearsal with three-dimensional models before low anterior resection: randomized clinical trial.

Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis (2020)
Journal Article
Fraser, S. D., Crooks, M. G., Kaye, P. M., & Hart, S. P. (2021). Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis. ERJ Open Research, 7(1), https://doi.org/10.1183/23120541.00804-2020

Background: In sarcoidosis, blood monocytes, circulating precursors of granuloma macrophages, display enhanced inflammatory cytokine production, reduced expression of the regulatory (inhibitory) receptor CD200R, and altered subsets defined by CD14 an... Read More about Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis.

The impact of surgical site infection on hospitalisation, treatment costs, and health-related quality of life after vascular surgery (2020)
Journal Article
Totty, J., Moss, J. W. E., Barker, E., Mealing, S., Posnett, J., Chetter, I. C., & Smith, G. E. (in press). The impact of surgical site infection on hospitalisation, treatment costs, and health-related quality of life after vascular surgery. International wound journal, https://doi.org/10.1111/iwj.13526

Surgical site infections (SSI) substantially increase costs for healthcare providers because of additional treatments and extended patient recovery. The objective of this study was to assess the cost and health‐related quality of life impact of SSI,... Read More about The impact of surgical site infection on hospitalisation, treatment costs, and health-related quality of life after vascular surgery.

Patient, family and carer experiences of nutritional screening: a systematic review (2020)
Journal Article
Bullock, A., Greenley, S. L., Patterson, M. J., McKenzie, G. A. G., & Johnson, M. J. (2021). Patient, family and carer experiences of nutritional screening: a systematic review. Journal of Human Nutrition and Dietetics, 34(3), 595-603. https://doi.org/10.1111/jhn.12849

Background: Despite recommendations for nutritional risk screening of all inpatients, outpatients and care home residents, as well as work to assess clinician's experiences and the validity of tools, little attention has been paid to the experiences... Read More about Patient, family and carer experiences of nutritional screening: a systematic review.

Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease (2020)
Journal Article
Helo, Y., Searle, G. E., Borghese, F., Abraham, S., & Saleem, A. (2020). Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease. EJNMMI Research, 10(1), Article 147. https://doi.org/10.1186/s13550-020-00736-9

© 2020, The Author(s). Objective: Expression of the translocator protein (TSPO) on inflammatory cells has facilitated imaging of synovitis with TSPO-targeted positron emission tomography (PET). We aimed to quantitatively assess the specificity of the... Read More about Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease.

Activation of PAR2 by tissue factor induces the release of the PTEN from MAGI proteins and regulates PTEN and Akt activities (2020)
Journal Article
Mohammad, M. A., Greenman, J., Maraveyas, A., & Ettelaie, C. (2020). Activation of PAR2 by tissue factor induces the release of the PTEN from MAGI proteins and regulates PTEN and Akt activities. Scientific reports, 10(1), Article 20908. https://doi.org/10.1038/s41598-020-77963-6

Tissue factor (TF) signalling has been associated with alterations in Akt activity influencing cellular survival and proliferation. TF is also shown to induce signalling through activation of the protease activated receptor (PAR)2. Seven cell lines w... Read More about Activation of PAR2 by tissue factor induces the release of the PTEN from MAGI proteins and regulates PTEN and Akt activities.

The surgical management of cutaneous abscesses: A UK cross-sectional survey (2020)
Journal Article
Thomas, O., Ramsay, A., Yiasemidou, M., Hardie, C., Ashmore, D., Macklin, C., Bandyopadhyay, D., Patel, B., Burke, J. R., & Jayne, D. (2020). The surgical management of cutaneous abscesses: A UK cross-sectional survey. Annals of Medicine and Surgery, 60, 654-659. https://doi.org/10.1016/j.amsu.2020.11.068

Aim
Cutaneous abscesses are one of the most common acute general surgery presentations. This study aimed to understand the current practice in the management of cutaneous abscesses in the United Kingdom (UK), once the decision has been made that acu... Read More about The surgical management of cutaneous abscesses: A UK cross-sectional survey.