Outputs (36)

The biomechanical role of the chondrocranium and the material properties of cartilage (2020)
Journal Article
Jones, M. E. H., Gröning, F., Aspden, R. M., Dutel, H., Sharp, A., Moazen, M., Fagan, M. J., & Evans, S. E. (2020). The biomechanical role of the chondrocranium and the material properties of cartilage. Vertebrate Zoology, 70(4), 699-715. https://doi.org/10.26049/VZ70-4-2020-10

The chondrocranium is the cartilage component of the vertebrate braincase. Among jawed vertebrates it varies greatly in structure, mineralisation, and in the extent to which it is replaced by bone during development. In mammals, birds, and some bony... Read More about The biomechanical role of the chondrocranium and the material properties of cartilage.

Characterizing and Modeling Bone Formation during Mouse Calvarial Development (2019)
Journal Article
Marghoub, A., Libby, J., Babbs, C., Ventikos, Y., Fagan, M. J., & Moazen, M. (2019). Characterizing and Modeling Bone Formation during Mouse Calvarial Development. Physical review letters, 122(4), Article 048103. https://doi.org/10.1103/PhysRevLett.122.048103

© 2019 American Physical Society. The newborn mammalian cranial vault consists of five flat bones that are joined together along their edges by soft fibrous tissues called sutures. Early fusion of these sutures leads to a medical condition known as c... Read More about Characterizing and Modeling Bone Formation during Mouse Calvarial Development.

Predicting calvarial growth in normal and craniosynostotic mice using a computational approach (2017)
Journal Article
Marghoub, A., Libby, J., Babbs, C., Pauws, E., Fagan, M. J., & Moazen, M. (2018). Predicting calvarial growth in normal and craniosynostotic mice using a computational approach. Journal of anatomy, 232(3), 440-448. https://doi.org/10.1111/joa.12764

© 2017 Anatomical Society During postnatal calvarial growth the brain grows gradually and the overlying bones and sutures accommodate that growth until the later juvenile stages. The whole process is coordinated through a complex series of biological... Read More about Predicting calvarial growth in normal and craniosynostotic mice using a computational approach.

Modelling human skull growth: a validated computational model (2017)
Journal Article
Libby, J., Marghoub, A., Johnson, D., Khonsari, R. H., Fagan, M. J., & Moazen, M. (2017). Modelling human skull growth: a validated computational model. Journal of the Royal Society interface / the Royal Society, 14(130), 20170202. https://doi.org/10.1098/rsif.2017.0202

© 2017 The Author(s) Published by the Royal Society. All rights reserved. During the first year of life, the brain grows rapidly and the neurocranium increases to about 65% of its adult size. Our understanding of the relationship between the biomecha... Read More about Modelling human skull growth: a validated computational model.

Computational biomechanics changes our view on insect head evolution (2017)
Journal Article
Blanke, A., Watson, P. J., Holbrey, R., & Fagan, M. J. (2017). Computational biomechanics changes our view on insect head evolution. Proceedings of the Royal Society B: Biological Sciences, 284(1848), Article 20162412. https://doi.org/10.1098/rspb.2016.2412

© 2017 The Author(s) Published by the Royal Society. All rights reserved. Despite large-scale molecular attempts, the relationships of the basal winged insect lineages dragonflies, mayflies and neopterans, are still unresolved. Other data sources, su... Read More about Computational biomechanics changes our view on insect head evolution.

Application of Far Cortical Locking Technology in Periprosthetic Femoral Fracture Fixation: A Biomechanical Study (2016)
Journal Article
Moazen, M., Leonidou, A., Pagkalos, J., Marghoub, A., Fagan, M. J., & Tsiridis, E. (2016). Application of Far Cortical Locking Technology in Periprosthetic Femoral Fracture Fixation: A Biomechanical Study. Journal of Arthroplasty, 31(8), 1849-1856. https://doi.org/10.1016/j.arth.2016.02.013

© 2016 Elsevier Inc. Background Lack of fracture movement could be a potential cause of periprosthetic femoral fracture (PFF) fixation failures. This study aimed to test whether the use of distal far cortical locking screws reduces the overall stiffn... Read More about Application of Far Cortical Locking Technology in Periprosthetic Femoral Fracture Fixation: A Biomechanical Study.

Intracranial pressure changes during mouse development (2015)
Journal Article
Moazen, M., Alazmani, A., Rafferty, K., Liu, Z.-J., Gustafson, J., Cunningham, M. L., Fagan, M. J., & Herring, S. W. (2016). Intracranial pressure changes during mouse development. Journal of biomechanics, 49(1), 123-126. https://doi.org/10.1016/j.jbiomech.2015.11.012

During early stages of postnatal development, pressure from the growing brain as well as cerebrospinal fluid, i.e. intracranial pressure (ICP), load the calvarial bones. It is likely that such loading contributes to the peripheral bone formation at t... Read More about Intracranial pressure changes during mouse development.

Validity and sensitivity of a human cranial finite element model: Implications for comparative studies of biting performance (2015)
Journal Article
Toro-Ibacache, V., Fitton, L. C., Fagan, M. J., & O'Higgins, P. (2016). Validity and sensitivity of a human cranial finite element model: Implications for comparative studies of biting performance. Journal of anatomy, 228(1), 70-84. https://doi.org/10.1111/joa.12384

Finite element analysis (FEA) is a modelling technique increasingly used in anatomical studies investigating skeletal form and function. In the case of the cranium this approach has been applied to both living and fossil taxa to (for example) investi... Read More about Validity and sensitivity of a human cranial finite element model: Implications for comparative studies of biting performance.

Mechanical properties of calvarial bones in a mouse model for craniosynostosis (2015)
Journal Article
Moazen, M., Peskett, E., Babbs, C., Pauws, E., & Fagan, M. J. (2015). Mechanical properties of calvarial bones in a mouse model for craniosynostosis. PLoS ONE, 10(5), e0125757. https://doi.org/10.1371/journal.pone.0125757

The mammalian cranial vault largely consists of five flat bones that are joined together along their edges by soft fibrous tissues called sutures. Premature closure of the cranial sutures, craniosynostosis, can lead to serious clinical pathology unle... Read More about Mechanical properties of calvarial bones in a mouse model for craniosynostosis.

Masticatory biomechanics in the rabbit: a multi-body dynamics analysis (2014)
Journal Article
Watson, P. J., Gröning, F., Curtis, N., Fitton, L. C., Herrel, A., McCormack, S. W., & Fagan, M. J. (2014). Masticatory biomechanics in the rabbit: a multi-body dynamics analysis. Journal of the Royal Society interface / the Royal Society, 11(99), Article 20140564. https://doi.org/10.1098/rsif.2014.0564

Multi-body dynamics is a powerful engineering tool which is becoming increasingly popular for the simulation and analysis of skull biomechanics. This paper presents the first application of multi-body dynamics to analyse the biomechanics of the rabbi... Read More about Masticatory biomechanics in the rabbit: a multi-body dynamics analysis.