Outputs (459)

Patient-reported outcome measures for allergy and asthma in children (2016)
Journal Article
Soyiri, I. N., Nwaru, B. I., & Sheikh, A. (2016). Patient-reported outcome measures for allergy and asthma in children. Pediatric Allergy and Immunology, 27(8), 779-783. https://doi.org/10.1111/pai.12603

There is increasing recognition of the importance of patient's perceptions of disease and their assessments of heathcare processes. Patient‐reported outcome measures (PROMs) are therefore now regarded as at least as important as the traditional objec... Read More about Patient-reported outcome measures for allergy and asthma in children.

Missing data in randomized controlled trials testing palliative interventions pose a significant risk of bias and loss of power: a systematic review and meta-analyses (2016)
Journal Article
Hussain, J. A., White, I. R., Langan, D., Johnson, M. J., Currow, D. C., Torgerson, D. J., & Bland, M. (2016). Missing data in randomized controlled trials testing palliative interventions pose a significant risk of bias and loss of power: a systematic review and meta-analyses. Journal of clinical epidemiology, 74, 57-65. https://doi.org/10.1016/j.jclinepi.2015.12.003

Objectives To assess the risk posed by missing data (MD) to the power and validity of trials evaluating palliative interventions. Study Design and Setting A systematic review of MD in published randomized controlled trials (RCTs) of palliative interv... Read More about Missing data in randomized controlled trials testing palliative interventions pose a significant risk of bias and loss of power: a systematic review and meta-analyses.

Exploratory trial of a school-based alcohol prevention intervention with a family component: Implications for implementation (2016)
Journal Article
Segrott, J., Rothwell, H., Pignatelli, I., Playle, R., Hewitt, G., Huang, C., Murphy, S., Hickman, M., Reed, H., & Moore, L. (2016). Exploratory trial of a school-based alcohol prevention intervention with a family component: Implications for implementation. Health Education, 116(4), 410-431. https://doi.org/10.1108/HE-01-2015-0005

Purpose – Involvement of parents/carers may increase effectiveness of primary school-based alcohol-misuse prevention projects through strengthening family-based protective factors, but rates of parental engagement are typically low. This paper report... Read More about Exploratory trial of a school-based alcohol prevention intervention with a family component: Implications for implementation.

Content and quality of websites supporting self-management of chronic breathlessness in advanced illness: a systematic review (2016)
Journal Article
Luckett, T., Disler, R., Hosie, A., Johnson, M., Davidson, P., Currow, D., Sumah, A., & Phillips, J. (2016). Content and quality of websites supporting self-management of chronic breathlessness in advanced illness: a systematic review. NPJ Primary Care Respiratory Medicine, 26(1), Article ARTN 16025. https://doi.org/10.1038/npjpcrm.2016.25

Chronic breathlessness is a common, burdensome and distressing symptom in many advanced chronic illnesses. Self-management strategies are essential to optimise treatment, daily functioning and emotional coping. People with chronic illness commonly se... Read More about Content and quality of websites supporting self-management of chronic breathlessness in advanced illness: a systematic review.

Building a recruitment database for asthma trials: a conceptual framework for the creation of the UK Database of Asthma Research Volunteers (2016)
Journal Article
Nwaru, B. I., Soyiri, I. N., Simpson, C. R., Griffiths, C., & Sheikh, A. (2016). Building a recruitment database for asthma trials: a conceptual framework for the creation of the UK Database of Asthma Research Volunteers. Trials, 17(1), Article 264. https://doi.org/10.1186/s13063-016-1381-6

Background
Randomised clinical trials are the ‘gold standard’ for evaluating the effectiveness of healthcare interventions. However, successful recruitment of participants remains a key challenge for many trialists. In this paper, we present a concep... Read More about Building a recruitment database for asthma trials: a conceptual framework for the creation of the UK Database of Asthma Research Volunteers.

A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication (2016)
Journal Article
Harwood, A., Smith, G. E., Cayton, T., Broadbent, E., & Chetter, I. C. (2016). A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication. Annals of vascular surgery, 34, 280-289. https://doi.org/10.1016/j.avsg.2016.02.009

Background Intermittent claudication (IC) is a common and debilitating symptom of peripheral arterial disease and is associated with a significant reduction in a sufferer's quality of life. Guidelines recommend a supervised exercise program (SEP) as... Read More about A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication.

A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: The ChildRen with eczema, antibiotic management (CREAM) study (2016)
Journal Article
Francis, N. A., Ridd, M. J., Thomas-Jones, E., Shepherd, V., Butler, C. C., Hood, K., Huang, C., Addison, K., Longo, M., Marwick, C., Wootton, M., Howe, R., Roberts, A., Haq, M. I.-U., Madhok, V., Sullivan, F., & on behalf of the CREAM team. (2016). A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: The ChildRen with eczema, antibiotic management (CREAM) study. Health Technology Assessment, 20(19), 1-84. https://doi.org/10.3310/hta20190

Background
Secondary skin infection is common during eczema exacerbations and many children are treated with antibiotics when this is suspected, although there is little high-quality evidence to justify this practice.

Objective
To determine the... Read More about A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: The ChildRen with eczema, antibiotic management (CREAM) study.

Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials (2016)
Journal Article
Temel, J. S., Abernethy, A. P., Currow, D. C., Friend, J., Duus, E. M., Yan, Y., & Fearon, K. C. (2016). Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials. The lancet oncology, 17(4), 519-531. https://doi.org/10.1016/S1470-2045%2815%2900558-6

© 2016 Elsevier Ltd Background Patients with advanced cancer frequently experience anorexia and cachexia, which are associated with reduced food intake, altered body composition, and decreased functionality. We assessed anamorelin, a novel ghrelin-re... Read More about Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials.

A mixed-methods, randomized controlled, feasibility trial to inform the design of a phase 3 trial to test the effect of the hand-held fan on physical activity and carer anxiety in patients with refractory breathlessness (2016)
Journal Article
Johnson, M. J., Booth, S., Currow, D. C., Lam, L. T., & Phillips, J. L. (2016). A mixed-methods, randomized controlled, feasibility trial to inform the design of a phase 3 trial to test the effect of the hand-held fan on physical activity and carer anxiety in patients with refractory breathlessness. Journal of pain and symptom management, 51(5), 807-815. https://doi.org/10.1016/j.jpainsymman.2015.11.026

Context The handheld fan is an inexpensive and safe way to provide facial airflow, which may reduce the sensation of chronic refractory breathlessness, a frequently encountered symptom. Objectives To test the feasibility of developing an adequately p... Read More about A mixed-methods, randomized controlled, feasibility trial to inform the design of a phase 3 trial to test the effect of the hand-held fan on physical activity and carer anxiety in patients with refractory breathlessness.

Extreme low-lying carotid bifurcations (2016)
Journal Article
Harwood, A. E., Leung, C. C. M., Smith, G. E., & Chetter, I. C. (2016). Extreme low-lying carotid bifurcations. Vascular Medicine, 21(4), 394-395. https://doi.org/10.1177/1358863X15627208

A 52-year-old male with no past medical history was referred to the transient ischaemic attack (TIA) clinic following an event at home. The transient symptoms were of an inability to move his left arm and leg for a period of approximately 15 minutes.... Read More about Extreme low-lying carotid bifurcations.