Outputs (459)

Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis (2017)
Journal Article
Boland, J. W., Allgar, V., Boland, E. G., Oviasu, O., Agar, M., Currow, D. C., & Johnson, M. J. (2017). Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis. Journal of palliative medicine, 20(11), 1274-1279. https://doi.org/10.1089/jpm.2017.0129

Background: Medications for symptom management in palliative care have associated, but poorly understood, harms. Drug-related harms have important clinical implications, may impact on patients’ compliance and contribute to symptoms. Objective: To exp... Read More about Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis.

Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review (2017)
Journal Article
Hussain, J. A., Johnson, M. J., Currow, D. C., White, I. R., Currow, D., Hussain, J., Johnson, M., Bland, M., Langan, D., & White, I. (2017). Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review. Journal of clinical epidemiology, 88, 81-91. https://doi.org/10.1016/j.jclinepi.2017.05.009

Objectives Assess (i) the quality of reporting and handling of missing data (MD) in palliative care trials, (ii) whether there are differences in the reporting of criteria specified by the Consolidated Standards of Reporting Trials (CONSORT) 2010 sta... Read More about Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review.

Cost-effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach (2017)
Journal Article
Vargas-Palacios, A., Meads, D. M., Twiddy, M., Murray, C. C., Hulme, C., Mitchell, E. D., Gregson, A., Stanley, P., & Minton, J. (2017). Cost-effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach. The journal of antimicrobial chemotherapy, 72(8), 2392-2400. https://doi.org/10.1093/jac/dkx123

© The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. Objectives: In the UK, patients who require intravenous antimicrobial (IVA) treatment may receive this in th... Read More about Cost-effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach.

Ignorability for general longitudinal data (2017)
Journal Article
Farewell, D. M., Huang, C., & Didelez, V. (2017). Ignorability for general longitudinal data. Biometrika, 104(2), 317-326. https://doi.org/10.1093/biomet/asx020

Likelihood factors that can be disregarded for inference are termed ignorable. We demonstrate that close ties exist between ignorability and identification of causal effects by covariate adjustment. A graphical condition, stability, plays a role anal... Read More about Ignorability for general longitudinal data.

Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery (2017)
Journal Article
Carradice, D., Chetter, I. C., Totty, J. P., Wallace, T., Bua, N., Pan, D., & Smith, G. E. (2017). Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery. Annals of vascular surgery, 44, 387-392. https://doi.org/10.1016/j.avsg.2017.03.198

© 2017 Elsevier Inc. Background Dressings coated with dialkylcarbamoyl chloride (DACC) are highly hydrophobic and irreversibly bind multiple types of bacteria, trapping them in the dressing and reducing the number of organisms at the wound surface. W... Read More about Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery.

Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness (2017)
Journal Article
Johnson, M. J., Yorke, J., Hansen-Flaschen, J., Lansing, R., Ekström, M., Similowski, T., & Currow, D. (2017). Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness. European respiratory journal, 49(5), Article 1602277. https://doi.org/10.1183/13993003.02277-2016

Copyright ©ERS 2017. Breathlessness that persists despite treatment for the underlying conditions is debilitating. Identifying this discrete entity as a clinical syndrome should raise awareness amongst patients, clinicians, service providers, researc... Read More about Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness.

NIHR Liver/Renal Biomarker Programme Final Report: Evaluating the benefits for patients and the NHS of new and existing biological fluid biomarkers in liver and renal disease (2017)
Report
Selby, P., Banks, R., Gregory, W., Hewison, J., Rosenberg, W., Altman, D., Deeks, J. J., McCabe, C., Parkes, J., Sturgeon, C., Thompson, D., Twiddy, M., Bestall, J., Bedlington, J., Hale, T., Dinnes, J., Jones, M., Lewington, A., Messenger, M. P., Napp, V., …Hutchinson, M. (2017). NIHR Liver/Renal Biomarker Programme Final Report: Evaluating the benefits for patients and the NHS of new and existing biological fluid biomarkers in liver and renal disease. Southampton: NIHR

Protein biomarkers are naturally occurring substances that can be measured, often in fluids such as blood or urine, and which provide information about a patient and their illness. Different diseases have different biomarkers. When people become ill,... Read More about NIHR Liver/Renal Biomarker Programme Final Report: Evaluating the benefits for patients and the NHS of new and existing biological fluid biomarkers in liver and renal disease.

Quality of life in patients with intermittent claudication (2017)
Journal Article
Harwood, A. E., Totty, J. P., Broadbent, E., Smith, G. E., & Chetter, I. C. (2017). Quality of life in patients with intermittent claudication. Gefässchirurgie, 22(3), 159-164. https://doi.org/10.1007/s00772-017-0269-4

© 2017, The Author(s). Background: Intermittent claudication (IC) is a common condition that causes pain in the lower limbs when walking and has been shown to severely impact the quality of life (QoL) of patients. The QoL is therefore often regarded... Read More about Quality of life in patients with intermittent claudication.

Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review (2017)
Journal Article
Murray, C. C., Mitchell, E. D., Czoski Murray, C., Meads, D., Minton, J., Wright, J., & Twiddy, M. (2017). Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review. BMJ open, 7(4), Article e013560. https://doi.org/10.1136/bmjopen-2016-013560

OBJECTIVE:
Evaluate evidence of the efficacy, safety, acceptability and cost-effectiveness of outpatient parenteral antimicrobial therapy (OPAT) models.
DESIGN:
A systematic review.
DATA SOURCES:
MEDLINE, EMBASE, CINAHL, Cochrane Library, National He... Read More about Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review.

Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups (2017)
Journal Article
Currow, D. C., Johnson, M. J., Dal Grande, E., Ekström, M., Ferreira, D., & McCaffrey, N. (2017). Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups. Thorax, 72(12), 1151-1153. https://doi.org/10.1136/thoraxjnl-2016-209908

© 2017 Published by the BMJ Publishing Group Limited. Little is known about the impact of chronic breathlessness (modified Medical Research Council (mMRC) score ≥2 for most days, at least three of the last six months) on health-related quality of lif... Read More about Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups.