Prevalence, symptom burden, and natural history of deep vein thrombosis in people with advanced cancer in specialist palliative care units (HIDDen): a prospective longitudinal observational study
White, Clare; Noble, Simon I R; Watson, Max; Swan, Flavia; Allgar, Victoria L; Napier, Eoin; Nelson, Annmarie; McAuley, Jayne; Doherty, Jennifer; Lee, Bernadette; Johnson, Miriam J
Simon I R Noble
Dr Flavia Swan F.Swan@hull.ac.uk
Research fellow in cancer rehabilitation
Victoria L Allgar
Professor Miriam Johnson Miriam.Johnson@hull.ac.uk
The prevalence of deep venous thrombosis in patients with advanced cancer is unconfirmed and it is unknown whether current international thromboprophylaxis guidance is applicable to this population. We aimed to determine prevalence and predictors of femoral deep vein thrombosis in patients admitted to specialist palliative care units (SPCUs).
We did this prospective longitudinal observational study in five SPCUs in England, Wales, and Northern Ireland (four hospices and one palliative care unit). Consecutive adults with cancer underwent bilateral femoral vein ultrasonography on admission and weekly until death or discharge for a maximum of 3 weeks. Data were collected on performance status, attributable symptoms, and variables known to be associated with venous thromboembolism. Patients with a short estimated prognosis (
|Journal Article Type||Article|
|Journal||The Lancet Haematology|
|Peer Reviewed||Peer Reviewed|
|APA6 Citation||White, C., Noble, S. I. R., Watson, M., Swan, F., Allgar, V. L., Napier, E., …Johnson, M. J. (2019). Prevalence, symptom burden, and natural history of deep vein thrombosis in people with advanced cancer in specialist palliative care units (HIDDen): a prospective longitudinal observational study. Lancet Haematology, 6(2), e79-e88. doi:10.1016/s2352-3026(18)30215-1|
|Additional Information||Copy of article first published in: Lancet Haematology, 2019, v.6, issue 2.|
©2019 The authors. This is an Open Access article under the CC BY-NC-ND 4.0 license.
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