Resistance training as a treatment for older persons with peripheral artery disease: A systematic review and meta-analysis

Parmenter, Belinda J.; Mavros, Yorgi; Ritti Dias, Raphael; King, Stephanie; Fiatarone Singh, Maria

Abstract

Objective: Resistance training (RT) improves walking ability in persons with peripheral artery disease. We conducted a meta-analysis of randomised controlled trials (RCTs) investigating the effect of RT on peripheral artery disease (as measured by walking ability). Design: We included RCTs that investigated the effect of RT on treadmill and/or 6 min walk (6-MWT) distances. RT intensity was assessed according to the American College of Sports Medicine guidelines by 1 repetition maximum or rating of perceived exertion. Standardised mean (SMD) and mean differences (MD) were calculated using a random-effects inverse variance model. Heterogeneity and bias were assessed using RevMan V.5.3. Meta-regression and meta-analysis of variance were performed as moderator analyses. Data sources: Databases (Medline, Embase, Web of Science, Cinahl and Google Scholar) were searched until July 2018. Results: Fifteen trials isolated RT; 7 trials compared RT with aerobic exercise. We analysed 826 patients (n=363 completing RT), with a mean age of 67.1±3.8 years. Training ranged from low-high intensity, 2-7 times per week for 17±7 weeks, with a mix of upper, lower or whole body training. Overall RT significantly improved constant load treadmill claudication onset (COD) (SMD 0.66 [0.40, 0.93], p

Citation

Parmenter, B. J., Mavros, Y., Ritti Dias, R., King, S., & Fiatarone Singh, M. (2019). Resistance training as a treatment for older persons with peripheral artery disease: A systematic review and meta-analysis. British journal of sports medicine, 1-11. https://doi.org/10.1136/bjsports-2018-100205

• Journal Article Type: Review
• Acceptance Date: Mar 23, 2019
• Online Publication Date: Apr 12, 2019
• Publication Date: Apr 13, 2019
• Deposit Date: Jun 11, 2019
• Publicly Available Date: Jun 12, 2019
• Journal: British Journal of Sports Medicine
• Print ISSN: 0306-3674
• Electronic ISSN: 1473-0480
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Pages: 1-11
• DOI: https://doi.org/10.1136/bjsports-2018-100205
• Keywords: Resistance training; Peripheral artery disease
• Public URL: https://hull-repository.worktribe.com/output/1928619
• Publisher URL: https://bjsm.bmj.com/content/early/2019/04/11/bjsports-2018-100205