Skip to main content

Research Repository

Advanced Search

A nine months follow-up study of hemodynamic effect on bioabsorbable coronary stent implantation

Lan, Yisha; Zhou, Yuanhang; Lu, Yiwen; Wang, Hao; Liu, Qing; Ng, E. Y. K.; Peng, Yonghong; Hao, Yongtao; Liu, Qinyuan; Chen, Fei; Cheng, Yongqiang; Che, Wenliang


Yisha Lan

Yuanhang Zhou

Yiwen Lu

Hao Wang

Qing Liu

E. Y. K. Ng

Yonghong Peng

Yongtao Hao

Qinyuan Liu

Fei Chen

Yongqiang Cheng

Wenliang Che


Coronary artery disease has emerged as one of the major diseases causing death worldwide. Coronary stent has great effect to improve blood flow to the myocardium subtended by that artery, in which bioresorbable vascular scaffolds are new-generation stents used by people. However, Coronary stents implantation has a risk of restenosis, which is relative to hemodynamic parameters. Most of existing literatures studied in this issue have not taken into account such important factors as the strut thickness and lumen profile, and has yet to analyze the time effects among hemodynamic parameters over a certain period of time based on individual models. In this research, we proposed a framework to assess the chronic impact of hemodynamic on coronary stent implantation. In the framework, the optical coherence tomography (OCT) is combined with angiography to reconstruct patient-specific models of bioresorbable vascular scaffolds. Then, the hemodynamics parameters are extracted through the simulated 3D models, obtaining the distribution of wall shear stress (WSS), relative residence time (RRT) and oscillatory shear index (OSI). Finally, the changes of these parameters representing the effectiveness of hemodynamics exerted on the implanted stent can be assessed to estimate the chronic impacts. By a 9-month follow-up case study, it is observed that the difference of hemodynamic parameters are not significance. Both at baseline and 9-month follow-up experiments show that the hemodynamic parameters remain normal and similar, proving that the coronary stent implantation nowadays appears to have a robust and everlasting curative effect.


Lan, Y., Zhou, Y., Lu, Y., Wang, H., Liu, Q., Ng, E. Y. K., …Che, W. (2019). A nine months follow-up study of hemodynamic effect on bioabsorbable coronary stent implantation. IEEE Access, 7, 112564-112571.

Journal Article Type Article
Acceptance Date Aug 6, 2019
Online Publication Date Aug 9, 2019
Publication Date Aug 9, 2019
Deposit Date Aug 30, 2019
Publicly Available Date Aug 30, 2019
Journal IEEE Access
Electronic ISSN 2169-3536
Publisher Institute of Electrical and Electronics Engineers
Peer Reviewed Peer Reviewed
Volume 7
Pages 112564-112571
Keywords Bioabsorbable vascular scaffolds; Optical coherence tomography; Computational fluid dynamics; Hemodynamic parameters at baseline; Nine months follow-up
Public URL
Publisher URL


Published article (1.5 Mb)

Copyright Statement
This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see

You might also like

Downloadable Citations