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Percutaneous transluminal angioplasty results in improved physical function but not balance in patients with intermittent claudication

Gohil, Risha Arun; Mockford, Katherine A.; Mazari, Fayyaz A.; Khan, Junaid A.; Van Vanicek, Natalie; Chetter, Ian C.; Coughlin, Patrick A.


Risha Arun Gohil

Katherine A. Mockford

Fayyaz A. Mazari

Junaid A. Khan

Patrick A. Coughlin


Objective The aim of this study was to identify whether revascularization by percutaneous transluminal angioplasty (PTA) for patients with intermittent claudication improved measures of functional performance including balance. Methods A prospective observational study was performed at a single tertiary vascular center. Patients with symptomatic intermittent claudication (Rutherford grades 1-3) were recruited to the study. Participants were assessed at baseline (pre-PTA) and then 3, 6, and 12 months post-PTA for markers of (1) lower limb ischemia (treadmill walking distances and ankle-brachial pressure index), (2) physical function (6-minute walk, Timed Up and Go, and chair stand time), (3) balance impairment using computerized dynamic posturography with the Sensory Organization Test, and (4) quality of life (VascuQoL and Short Form Health Survey [SF-36]). Results Forty-three participants underwent PTA. Over 12 months, a significant improvement was demonstrated in initial (P = .04) and maximum treadmill walking distance (P = .019). Physical functional ability improved across all outcome measures (P < .02), and some domains of both generic (P < .03) and disease-specific quality of life (P < .01). No significant improvement in balance was demonstrated by the Sensory Organization Test (P = .24). Conclusions Balance impairment is common in claudicants and does not improve with revascularization. Further research regarding effective treatment of balance impairment is required in this specific group of patients.


Gohil, R. A., Mockford, K. A., Mazari, F. A., Khan, J. A., Van Vanicek, N., Chetter, I. C., & Coughlin, P. A. (2013). Percutaneous transluminal angioplasty results in improved physical function but not balance in patients with intermittent claudication. Journal of vascular surgery, 58(6), 1533-1539.

Journal Article Type Article
Acceptance Date May 24, 2013
Online Publication Date Jul 20, 2013
Publication Date 2013-12
Deposit Date Jul 9, 2015
Publicly Available Date Jul 9, 2015
Journal Journal of vascular surgery
Print ISSN 0741-5214
Electronic ISSN 1097-6809
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 58
Issue 6
Pages 1533-1539
Keywords Percutaneous transluminal angioplasty, Intermittent claudication, Balance, Physical function
Public URL
Publisher URL
Additional Information Authors' accepted manuscript of article published in: Journal of vascular surgery, 2013, v.58, issue 6


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