Skip to main content

Research Repository

Advanced Search

Effect of supervised exercise on physical function and balance in patients with intermittent claudication

Mockford, K. A.; Gohil, R. A.; Mazari, F.; Khan, J. A.; Vanicek, N.; Coughlin, P. A.; Chetter, I. C.


K. A. Mockford

R. A. Gohil

F. Mazari

J. A. Khan

P. A. Coughlin


Background The aim of the study was to identify whether a standard supervised exercise programme (SEP) for patients with intermittent claudication improved specific measures of functional performance including balance. Methods A prospective observational study was performed at a single tertiary vascular centre. Patients with symptomatic intermittent claudication (Rutherford grades 1–3) were recruited to the study. Participants were assessed at baseline (before SEP) and 3, 6 and 12 months afterwards for markers of lower-limb ischaemia (treadmill walking distance and ankle : brachial pressure index), physical function (6-min walk, Timed Up and Go test, and Short Physical Performance Battery (SPPB) score), balance impairment using computerized dynamic posturography with the Sensory Organization Test (SOT), and quality of life (VascuQoL and Short Form 36). Results Fifty-one participants underwent SEP, which significantly improved initial treadmill walking distance (P = 0·001). Enrolment in a SEP also resulted in improvements in physical function as determined by 6-min maximum walking distance (P = 0·006), SPPB score (P < 0·001), and some domains of both generic (bodily pain, P = 0·025) and disease-specific (social domain, P = 0·039) quality of life. Significant improvements were also noted in balance, as determined by the SOT (P < 0·001). Conclusion Supervised exercise improves both physical function and balance impairment.


Mockford, K. A., Gohil, R. A., Mazari, F., Khan, J. A., Vanicek, N., Coughlin, P. A., & Chetter, I. C. (2014). Effect of supervised exercise on physical function and balance in patients with intermittent claudication. British journal of surgery, 101(4), 356-362.

Journal Article Type Article
Acceptance Date Nov 13, 2013
Online Publication Date Feb 3, 2014
Publication Date 2014-03
Deposit Date Jul 16, 2015
Publicly Available Date Jul 16, 2015
Journal British journal of surgery
Print ISSN 0007-1323
Electronic ISSN 1365-2168
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 101
Issue 4
Pages 356-362
Keywords Intermittent claudication; Balance; Physical function; Exercise
Public URL
Publisher URL
Additional Information Author's accepted manuscript of article published in: British journal of surgery, 2014, v.101, issue 4


You might also like

Downloadable Citations