Dr Laura Sadofsky L.R.Sadofsky@hull.ac.uk
Senior Lecturer in Respiratory Medicine
Dr Laura Sadofsky L.R.Sadofsky@hull.ac.uk
Senior Lecturer in Respiratory Medicine
Gerard Cantero-Recasens
Caroline Wright
Miguel A. Valverde
Professor Alyn Morice A.H.Morice@hull.ac.uk
Foundation Chair and Professor of Respiratory Medicine
Capsaicin, the hot component of chilli peppers, is a well-known tussive agent, which is regularly used as a tool to study cough and antitussives (1). Capsaicin is known to activate the transient receptor potential vanilloid 1 (TRPV1) cation channel which is thought to be involved in pain perception, inflammation, itch and cough (2-4). These functions within the body make TRPV1 an exciting target for research and drug development.
Sadofsky, L. R., Cantero-Recasens, G., Wright, C., Valverde, M. A., & Morice, A. H. (2017). TRPV1 polymorphisms influence capsaicin cough sensitivity in men. Journal of thoracic disease, 9(3), 839-840. https://doi.org/10.21037/jtd.2017.03.50
Journal Article Type | Article |
---|---|
Acceptance Date | Feb 6, 2017 |
Publication Date | Mar 1, 2017 |
Deposit Date | Feb 24, 2017 |
Journal | Journal of thoracic disease |
Print ISSN | 2072-1439 |
Peer Reviewed | Peer Reviewed |
Volume | 9 |
Issue | 3 |
Pages | 839-840 |
DOI | https://doi.org/10.21037/jtd.2017.03.50 |
Keywords | capsaicin, cough, genetic polymorphism, TRPV1, cough, polymorphism, TRPV1 |
Public URL | https://hull-repository.worktribe.com/output/448853 |
Publisher URL | http://jtd.amegroups.com/article/view/12417 |
Additional Information | This is a description of an article accepted for publication in Journal of thoracic disease, 2017, v.9 issue 3. Full text is not currently available in this repository. |
Contract Date | Feb 24, 2017 |
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