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The association between completion of supervised exercise therapy and long-term outcomes in patients with intermittent claudication, concomitant sarcopenia and cardiometabolic multimorbidity (2024)
Journal Article
Ravindhran, B., Igwe, C., Nazir, S., Harwood, A., Lathan, R., Carradice, D., Smith, G., Chetter, I., & Pymer, S. (in press). The association between completion of supervised exercise therapy and long-term outcomes in patients with intermittent claudication, concomitant sarcopenia and cardiometabolic multimorbidity. Annals of vascular surgery,

Tailored risk assessment and forecasting in intermittent claudication (2024)
Journal Article
Ravindhran, B., Prosser, J., Lim, A., Lathan, R., Mishra, B., Hitchman, L., Smith, G. E., Carradice, D., Thakker, D., Chetter, I. C., & Pymer, S. (2024). Tailored risk assessment and forecasting in intermittent claudication. BJS Open, 8(1), Article zrad166. https://doi.org/10.1093/bjsopen/zrad166

Background: Guidelines recommend cardiovascular risk reduction and supervised exercise therapy as the first line of treatment in intermittent claudication, but implementation challenges and poor patient compliance lead to significant variation in man... Read More about Tailored risk assessment and forecasting in intermittent claudication.

Supervised Exercise Therapy for Intermittent Claudication: A Propensity Score Matched Analysis of Retrospective Data on Long Term Cardiovascular Outcomes (2023)
Journal Article
Ravindhran, B., Lim, A. J., Kurian, T., Walshaw, J., Hitchman, L. H., Lathan, R., Smith, G. E., Carradice, D., Chetter, I. C., & Pymer, S. (in press). Supervised Exercise Therapy for Intermittent Claudication: A Propensity Score Matched Analysis of Retrospective Data on Long Term Cardiovascular Outcomes. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, https://doi.org/10.1016/j.ejvs.2023.11.040

Objective: This study aimed to explore the long term outcomes of patients with intermittent claudication (IC) who completed supervised exercise therapy (SET) vs. those who declined or prematurely discontinued SET, focusing on the incidence of chronic... Read More about Supervised Exercise Therapy for Intermittent Claudication: A Propensity Score Matched Analysis of Retrospective Data on Long Term Cardiovascular Outcomes.

Molecular mechanisms of action of negative pressure wound therapy: A systematic review (2023)
Journal Article
Ravindhran, B., Schafer, N., Howitt, A., Carradice, D., Smith, G., & Chetter, I. (2023). Molecular mechanisms of action of negative pressure wound therapy: A systematic review. Expert Reviews in Molecular Medicine, 25, Article e29. https://doi.org/10.1017/erm.2023.24

Negative pressure wound therapy (NPWT) has significantly advanced wound care and continues to find new applications. Its effects at a molecular level however, remain a subject of debate. The aim of this systematic review is to summarize the current e... Read More about Molecular mechanisms of action of negative pressure wound therapy: A systematic review.

Long term outcomes of ‘Christmas Tree’ banding for haemodialysis access induced distal ischemia: A 13-year experience (2022)
Journal Article
Ravindhran, B., Totty, J. P., Sidapra, M., Lathan, R., Carradice, D., Chetter, I. C., & Smith, G. E. (in press). Long term outcomes of ‘Christmas Tree’ banding for haemodialysis access induced distal ischemia: A 13-year experience. The journal of vascular access, https://doi.org/10.1177/11297298221141497

Background: The reduction in distal arterial flow following arteriovenous fistula (AVF) creation can cause a perfusion deficit known as haemodialysis access induced distal ischemia (HAIDI). Various techniques have been advocated to treat this difficu... Read More about Long term outcomes of ‘Christmas Tree’ banding for haemodialysis access induced distal ischemia: A 13-year experience.

Extracorporeal shockwave therapy compared with standard care for diabetic foot ulcer healing: An updated systematic review (2022)
Journal Article
Hitchman, L., Totty, J., Smith, G. E., Carradice, D., Twiddy, M., Iglesias, C., Russell, D., & Chetter, I. C. (2022). Extracorporeal shockwave therapy compared with standard care for diabetic foot ulcer healing: An updated systematic review. International wound journal, https://doi.org/10.1111/iwj.14035

Emerging evidence suggests that extracorporeal shockwave therapy (ESWT) may improve time to DFU healing. The aim of this review was to appraise the evidence on role of ESWT in DFU healing and impact of different ESWT doses. Databases were searched fo... Read More about Extracorporeal shockwave therapy compared with standard care for diabetic foot ulcer healing: An updated systematic review.

Provision of NICE-recommended varicose vein treatment in the NHS (2022)
Journal Article
Hitchman, L., Mohamed, A., Smith, G. E., Pymer, S., Chetter, I. C., Forsyth, J., & Carradice, D. (2023). Provision of NICE-recommended varicose vein treatment in the NHS. British journal of surgery, 110(2), 225-232. https://doi.org/10.1093/bjs/znac392

BACKGROUND: Standardization of access to treatment and compliance with clinical guidelines are important to ensure the delivery of high-quality care to people with varicose veins. In the National Health Service (NHS) in England, commissioning of care... Read More about Provision of NICE-recommended varicose vein treatment in the NHS.

Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: protocol for a systematic review and meta-analysis (2022)
Journal Article
Ravindhran, B., Lathan, R., Staniland, T., Sidapra, M., Carradice, D., Chetter, I., Smith, G., Saxton, J., & Pymer, S. (2022). Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: protocol for a systematic review and meta-analysis. Journal of Vascular Societies Great Britain and Ireland, 2(1), 41-45. https://doi.org/10.54522/jvsgbi.2022.042

Background and objectives: The aim of this systematic review is to explore the current evidence surrounding the changes in functional status following open or endovascular abdominal aortic aneurysm (AAA) repair and the role of postoperative exercise-... Read More about Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: protocol for a systematic review and meta-analysis.

Compression following treatment of superficial venous incompetence: systematic review (2022)
Journal Article
Mohamed, A. H., Thadani, S., Mohamed, S. H., Sidapra, M., Smith, G., Chetter, I., & Carradice, D. (2022). Compression following treatment of superficial venous incompetence: systematic review. British journal of surgery, 109(8), 679-685. https://doi.org/10.1093/bjs/znac116

BACKGROUND: International guidelines recommend postprocedural compression when treating symptomatic superficial venous incompetence (SVI). This updated review of RCTs investigated the requirement for postprocedural compression and how it can be appli... Read More about Compression following treatment of superficial venous incompetence: systematic review.

Measurement of the local physiological effects of a single use topical negative pressure device in healthy volunteers– The PICO-1 Study (2022)
Journal Article
Prabakaran, P., Totty, J., Carradice, D., Chetter, I., & Smith, G. (in press). Measurement of the local physiological effects of a single use topical negative pressure device in healthy volunteers– The PICO-1 Study. Journal of Wound Care,

Aims This study aimed to investigate the effects of a Single use Negative Pressure Wound Therapy (sNPWT) device upon tissue perfusion, oxygenation and pressure, in the intact skin of healthy volunteers. Methods 12 healthy volunteers wore a PIC... Read More about Measurement of the local physiological effects of a single use topical negative pressure device in healthy volunteers– The PICO-1 Study.

A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access (2020)
Journal Article
Eves, J., Cai, P., Latham, R., Leung, C., Carradice, D., Chetter, I., & Smith, G. (in press). A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access. The journal of vascular access, https://doi.org/10.1177/1129729820954725

Background: Arteriovenous fistulae (AVF) are preferred for dialysis access but require accurate cannulation for effective dialysis. Evidence supports improvements in cannulation and complication rates using ultrasound guidance (USG) in cannulating ot... Read More about A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access.

A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection (2019)
Journal Article
Totty, J. P., Hitchman, L. H., Cai, P. L., Wallace, T., Harwood, A. E., Carradice, D., Smith, G. E., & Chetter, I. C. (2019). A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection. International wound journal, 16(4), 883-890. https://doi.org/10.1111/iwj.13113

A surgical site infection (SSI) may occur in up to 30% of procedures and results in significant morbidity and mortality. We aimed to assess the feasibility of conducting a randomised controlled trial (RCT) examining the use of dialkylcarbamoylchlorid... Read More about A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection.

Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication (2018)
Journal Article
Harwood, A. E., Totty, J. P., Pymer, S., Huang, C., Hitchman, L., Carradice, D., Wallace, T., Smith, G. E., & Chetter, I. C. (2019). Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication. Journal of vascular surgery, 69(6), 1899-1908.e1. https://doi.org/10.1016/j.jvs.2018.10.065

Objective Intermittent claudication occurs in 20 % of the population over 70 and treatment includes a supervised exercise programme (SEP). Whilst there is evidence demonstrating walking improvements following a SEP there is conflicting data on the ph... Read More about Cardiovascular and musculoskeletal response to supervised exercise in patients with intermittent claudication.

Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery (2017)
Journal Article
Carradice, D., Chetter, I. C., Totty, J. P., Wallace, T., Bua, N., Pan, D., & Smith, G. E. (2017). Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery. Annals of vascular surgery, 44, 387-392. https://doi.org/10.1016/j.avsg.2017.03.198

© 2017 Elsevier Inc. Background Dressings coated with dialkylcarbamoyl chloride (DACC) are highly hydrophobic and irreversibly bind multiple types of bacteria, trapping them in the dressing and reducing the number of organisms at the wound surface. W... Read More about Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery.

Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial) (2017)
Journal Article
Harwood, A. E., Smith, G. E., Totty, J. P., Carradice, D., Chetter, I. C., Harwood, A., Totty, J., Cayton, T., & Smith, G. (2017). Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial). Trials, 18(1), https://doi.org/10.1186/s13063-017-1844-4

© 2017 The Author(s). Background: Peripheral arterial disease (PAD) has a population prevalence of 4.6% with intermittent claudication (IC) presenting as one of the earliest and most common symptoms. PAD has detrimental effects on patients' walking a... Read More about Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial).

Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review (2017)
Journal Article
Totty, J., Bua, N., Smith, G., Harwood, A., Carradice, D., Wallace, T., & Chetter, I. (2017). Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review. Journal of Wound Care, 26(3), 107-114. https://doi.org/10.12968/jowc.2017.26.3.107

Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed. They are a recent addition to the wound care profe... Read More about Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review.

A systematic review of management of inadvertent arterial injury during central venous catheterisation (2016)
Journal Article
Dixon, O. G. B., Smith, G. E., Carradice, D., & Chetter, I. C. (2017). A systematic review of management of inadvertent arterial injury during central venous catheterisation. The journal of vascular access, 18(2), 97-102. https://doi.org/10.5301/jva.5000611

© 2017 Wichtig Publishing. Introduction: Central venous catheterisation (CVC) is a technique commonly used to obtain vascular access and over five million CVCs are inserted annually. This systematic review of CVC-related arterial injury aims to compa... Read More about A systematic review of management of inadvertent arterial injury during central venous catheterisation.

A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis (2015)
Journal Article
Smith, G. E., Souroullos, P., Cayton, T., Harwood, A., Carradice, D., & Chetter, I. C. (2016). A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis. The journal of vascular access, 17(1), 1-5. https://doi.org/10.5301/jva.5000484

Purpose: Surgical arteriovenous fistula (AVF) or graft (AVG) is preferred to a central venous catheter for dialysis access. Surgical access may suffer thrombosis early after placement and systemic anticoagulation during surgical access formation may... Read More about A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis.

Systematic review of compression following treatment for varicose veins (2015)
Journal Article
El-Sheikha, J., Carradice, D., Nandhra, S., Leung, C., Smith, G., Campbell, B., & Chetter, I. (2015). Systematic review of compression following treatment for varicose veins. British journal of surgery, 102(7), 719-725. https://doi.org/10.1002/bjs.9788

Background Consensus regarding compression following treatment of varicose veins has yet to be reached. This systematic review aims to establish the optimal compression regimen after venous treatment. Methods A systematic review of MEDLINE, Embase an... Read More about Systematic review of compression following treatment for varicose veins.