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Sigma-1 receptors modulate neonatal Nav1.5 ion channels in breast cancer cell lines (2016)
Journal Article
Aydar, E., Stratton, D., Fraser, S. P., Djamgoz, M. B., & Palmer, C. (2016). Sigma-1 receptors modulate neonatal Nav1.5 ion channels in breast cancer cell lines. European Biophysics Journal, 45(7), 671-683. doi:10.1007/s00249-016-1135-0

The main aim of this study was to investigate a possible functional connection between sigma-1 receptors and voltage-gated sodium channels (VGSCs) in human breast cancer cells. The hypothesis was that sigma-1 drugs could alter the metastatic properti... Read More

Pulsed extremely low-frequency magnetic fields stimulate microvesicle release from human monocytic leukaemia cells (2012)
Journal Article
Stratton, D., Lange, S., & Inal, J. M. (2013). Pulsed extremely low-frequency magnetic fields stimulate microvesicle release from human monocytic leukaemia cells. Biochemical and biophysical research communications, 430(2), 470-475. doi:10.1016/j.bbrc.2012.12.012

Microvesicles are released from cell surfaces constitutively during early apoptosis or upon activation with various stimuli including sublytic membrane attack complex (MAC). This study shows that an alternating current, pulsed, extremely low-frequenc... Read More