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All Outputs (16)

Microbes and us: microbiology literacy in Greece (2024)
Journal Article
Karayanni, H., Motsiou, E., Sapountzi, V., Meggou, L., Pagkoutsou, M., Triantafyllidi, A., …Efthimiou, G. (2024). Microbes and us: microbiology literacy in Greece. FEMS microbiology letters, 371, Article fnae008. https://doi.org/10.1093/femsle/fnae008

Microbes are ubiquitous and provide numerous services to humans and our planet. However, a query arises as to whether these microbial services are valued by the general public especially after unprecedented conditions like the COVID-19 pandemic. In t... Read More about Microbes and us: microbiology literacy in Greece.

Multi-dimensional experimental and computational exploration of metabolism pinpoints complex probiotic interactions (2023)
Journal Article
Zampieri, G., Efthimiou, G., & Angione, C. (2023). Multi-dimensional experimental and computational exploration of metabolism pinpoints complex probiotic interactions. Metabolic Engineering, 76, 120-132. https://doi.org/10.1016/j.ymben.2023.01.008

Multi-strain probiotics are widely regarded as effective products for improving gut microbiota stability and host health, providing advantages over single-strain probiotics. However, in general, it is unclear to what extent different strains would co... Read More about Multi-dimensional experimental and computational exploration of metabolism pinpoints complex probiotic interactions.

Airborne transmission of biological agents within the indoor built environment: a multidisciplinary review (2022)
Journal Article
Argyropoulos, C. D., Skoulou, V., Efthimiou, G., & Michopoulos, A. K. (2022). Airborne transmission of biological agents within the indoor built environment: a multidisciplinary review. Air Quality, Atmosphere and Health, https://doi.org/10.1007/s11869-022-01286-w

The nature and airborne dispersion of the underestimated biological agents, monitoring, analysis and transmission among the human occupants into building environment is a major challenge of today. Those agents play a crucial role in ensuring comforta... Read More about Airborne transmission of biological agents within the indoor built environment: a multidisciplinary review.

A guide to pedagogical research for scientists from a biological sciences background (2022)
Journal Article
Lacey, M. M., & Efthimiou, G. (2022). A guide to pedagogical research for scientists from a biological sciences background. Access Microbiology, 4(8), Article 416. https://doi.org/10.1099/acmi.0.000416

How we teach science and engage with the public, particularly in fast moving subjects such as microbiology, are constantly being reflected upon, improved and innovated. This has led to a significant increase of pedagogy publications by microbiology e... Read More about A guide to pedagogical research for scientists from a biological sciences background.

In Silico Genomic and Metabolic Atlas of Limosilactobacillus reuteri DSM 20016: An Insight into Human Health (2022)
Journal Article
Smythe, P., & Efthimiou, G. (2022). In Silico Genomic and Metabolic Atlas of Limosilactobacillus reuteri DSM 20016: An Insight into Human Health. Microorganisms, 10(7), Article 1341. https://doi.org/10.3390/microorganisms10071341

Probiotics are bacterial strains that are known to provide host health benefits. Limosilacto-bacillus reuteri is a well-documented lactic acid bacterium that has been cultured from numerous human sites. The strain investigated was L. reuteri DSM 2001... Read More about In Silico Genomic and Metabolic Atlas of Limosilactobacillus reuteri DSM 20016: An Insight into Human Health.

Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function (2021)
Journal Article
Huang, J., Peng, J., Pearson, J. A., Efthimiou, G., Hu, Y., Tai, N., Xing, Y., Zhang, L., Gu, J., Jiang, J., Zhao, H., Zhou, Z., Wong, F. S., & Wen, L. (2021). Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function. Cellular and Molecular Immunology, 18(2), 328-338. https://doi.org/10.1038/s41423-020-00590-8

Innate immunity mediated by Toll-like receptors (TLRs), which can recognize pathogen molecular patterns, plays a critical role in type 1 diabetes development. TLR7 is a pattern recognition receptor that senses single-stranded RNAs from viruses and ho... Read More about Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function.

Association Between Breastfeeding and the Development of Childhood Diabetes Mellitus Type I (DM I): The Effect of Prolonged Exclusive Breastfeeding on Gut Microbiome and the Link with DM I (2020)
Journal Article
Karagkouni, I., Sideridou, M., Stoupi, S., & Efthimiou, G. (2021). Association Between Breastfeeding and the Development of Childhood Diabetes Mellitus Type I (DM I): The Effect of Prolonged Exclusive Breastfeeding on Gut Microbiome and the Link with DM I. Acta scientific paediatrics, 4(1), 28-32

The role of breastfeeding and dietary habits was studied in 10 children with DM I (case group) and compared with 10 healthy controls. Our results showed that the case group had significantly shorter exclusive breastfeeding duration compared with the... Read More about Association Between Breastfeeding and the Development of Childhood Diabetes Mellitus Type I (DM I): The Effect of Prolonged Exclusive Breastfeeding on Gut Microbiome and the Link with DM I.

Antibiofilm activity of heather and manuka honeys and antivirulence potential of some of their constituents on the DsbA1 enzyme of pseudomonas aeruginosa (2020)
Journal Article
Shirlaw, O., Billah, Z., Attar, B., Hughes, L., Qasaymeh, R. M., Seidel, V., & Efthimiou, G. (2020). Antibiofilm activity of heather and manuka honeys and antivirulence potential of some of their constituents on the DsbA1 enzyme of pseudomonas aeruginosa. Antibiotics, 9(12), 1-12. https://doi.org/10.3390/antibiotics9120911

Heather honey was tested for its effect on the formation of biofilms by Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, Salmonella Enteriditis and Acinetobacter baumanii in comparison wit... Read More about Antibiofilm activity of heather and manuka honeys and antivirulence potential of some of their constituents on the DsbA1 enzyme of pseudomonas aeruginosa.

Microbes Against Humanity, a workshop game for horrible students: using a creative card game in higher education microbiology teaching (2020)
Journal Article
Efthimiou, G., & Tucker, N. P. (2020). Microbes Against Humanity, a workshop game for horrible students: using a creative card game in higher education microbiology teaching. Access Microbiology, https://doi.org/10.1099/acmi.0.000186

Introducing creative workshops in higher education curricula, in addition to formal lectures, is an excellent way of reinforcing knowledge and encouraging creative thinking. In particular, the use of card games as a tool for inducing student engageme... Read More about Microbes Against Humanity, a workshop game for horrible students: using a creative card game in higher education microbiology teaching.

Investigation of the physiology and architecture of Salmonella Enteritidis biofilms under alkaline conditions (2020)
Journal Article
Papakonstantinou, A., & Efthimiou, G. (2020). Investigation of the physiology and architecture of Salmonella Enteritidis biofilms under alkaline conditions. Acta Scientific Microbiology, 3(3), 1-11

Formation of bacterial biοfilms is an important survival strategy in multiple adverse environments. It is often affected by the nature of the attachment surface, the bacterial strain and the surrounding physicochemical conditions. The effect of low p... Read More about Investigation of the physiology and architecture of Salmonella Enteritidis biofilms under alkaline conditions.

Transcriptomic Adjustments of Staphylococcus aureus COL (MRSA) Forming Biofilms Under Acidic and Alkaline Conditions (2019)
Journal Article
Efthimiou, G., Tsiamis, G., Typas, M., & Pappas, K. (2019). Transcriptomic Adjustments of Staphylococcus aureus COL (MRSA) Forming Biofilms Under Acidic and Alkaline Conditions. Frontiers in Microbiology, 10, Article 02393. https://doi.org/10.3389/fmicb.2019.02393

© Copyright © 2019 Efthimiou, Tsiamis, Typas and Pappas. Methicillin-resistant Staphylococcus aureus (MRSA) strains are important human pathogens and a significant health hazard for hospitals and the food industry. They are resistant to β-lactam anti... Read More about Transcriptomic Adjustments of Staphylococcus aureus COL (MRSA) Forming Biofilms Under Acidic and Alkaline Conditions.

Olive Pomace Oil can be Used as an Alternative Carbon Source for Clavulanic Acid Production by Streptomyces clavuligerus (2019)
Journal Article
Young, T., Li, Y., & Efthimiou, G. (2020). Olive Pomace Oil can be Used as an Alternative Carbon Source for Clavulanic Acid Production by Streptomyces clavuligerus. Waste and biomass valorization, 11(8), 3965-3970. https://doi.org/10.1007/s12649-019-00719-5

Clavulanic acid is an important drug, both medically and economically. It is used to combat bacterial resistance to β-lactam antibiotics and is on the World Health Organisation’s List of Essential Medicines in combination with amoxicillin. An olive o... Read More about Olive Pomace Oil can be Used as an Alternative Carbon Source for Clavulanic Acid Production by Streptomyces clavuligerus.

Effect of rocket (Eruca sativa) extract on MRSA growth and proteome: Metabolic adjustments in plant-based media (2017)
Journal Article
Doulgeraki, A. I., Efthimiou, G., Paramithiotis, S., Pappas, K. M., Typas, M. A., & Nychas, G. J. (2017). Effect of rocket (Eruca sativa) extract on MRSA growth and proteome: Metabolic adjustments in plant-based media. Frontiers in Microbiology, 8(MAY), Article 782. https://doi.org/10.3389/fmicb.2017.00782

The emergence of methicillin-resistant Staphylococcus aureus (MRSA) in food has provoked a great concern about the presence of MRSA in associated foodstuff. Although MRSA is often detected in various retailed meat products, it seems that food handler... Read More about Effect of rocket (Eruca sativa) extract on MRSA growth and proteome: Metabolic adjustments in plant-based media.

Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2) (2011)
Journal Article
Lewis, R. A., Shahi, S. K., Laing, E., Bucca, G., Efthimiou, G., Bushell, M., & Smith, C. P. (2011). Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2). BMC research notes, 4(1), Article 78. https://doi.org/10.1186/1756-0500-4-78

Background: The present study represents a genome-wide transcriptomic analysis of the response of the model streptomycete Streptomyces coelicolor A3(2) M145 to fermentor culture in Modified Evans Media limited, respectively, for nitrogen, phosphate a... Read More about Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2).

A novel finding that Streptomyces clavuligerus can produce the antibiotic clavulanic acid using olive oil as a sole carbon source (2008)
Journal Article
Efthimiou, G., Thumser, A. E., & Avignone-Rossa, C. A. (2008). A novel finding that Streptomyces clavuligerus can produce the antibiotic clavulanic acid using olive oil as a sole carbon source. Journal of applied microbiology, 105(6), 2058-2064. https://doi.org/10.1111/j.1365-2672.2008.03975.x

Aims: This study aims to establish whether commercially available food oils can be used by Streptomyces clavuligerus as sole carbon sources for growth and clavulanic acid production. Methods and results: Batch cultures in bioreactors showed that Stre... Read More about A novel finding that Streptomyces clavuligerus can produce the antibiotic clavulanic acid using olive oil as a sole carbon source.