All Outputs (70)

Influence of step length on 6-minute walk test performance in patients with chronic heart failure (2011)
Journal Article
Pepera, G. K., Sandercock, G. R., Sloan, R., Cleland, J. J., Ingle, L., & Clark, A. L. (2012). Influence of step length on 6-minute walk test performance in patients with chronic heart failure. Physiotherapy, 98(4), 325-329. https://doi.org/10.1016/j.physio.2011.08.005

Objective: To investigate the influence of gait parameters including step length and walking speed during performance of the 6-minute walking test (6MWT) in patients with chronic heart failure (CHF). Design: Observational study. Setting: Specialist h... Read More about Influence of step length on 6-minute walk test performance in patients with chronic heart failure.

Prevalence of scarred and dysfunctional myocardium in patients with heart failure of ischaemic origin: A cardiovascular magnetic resonance study (2011)
Journal Article
Bourantas, C. V., Nikitin, N. P., Loh, H. P., Lukaschuk, E. I., Sherwi, N., de Silva, R., Tweddel, A. C., Alamgir, M. F., Wong, K., Gupta, S., Clark, A. L., & Cleland, J. G. (2011). Prevalence of scarred and dysfunctional myocardium in patients with heart failure of ischaemic origin: A cardiovascular magnetic resonance study. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 13(53), Article ARTN 53. https://doi.org/10.1186/1532-429x-13-53

BackgroundCardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) can provide unique data on the transmural extent of scar/viability. We assessed the prevalence of dysfunctional myocardium, including partial thickness scar, whi... Read More about Prevalence of scarred and dysfunctional myocardium in patients with heart failure of ischaemic origin: A cardiovascular magnetic resonance study.

Experiences of air travel in patients with chronic heart failure (2011)
Journal Article
Ingle, L., Hobkirk, J., Damy, T., Nabb, S., Clark, A. L., & Cleland, J. G. (2012). Experiences of air travel in patients with chronic heart failure. International journal of cardiology, 158(1), 66-70. https://doi.org/10.1016/j.ijcard.2010.12.101

AIM: To conduct a survey in a representative cohort of ambulatory patients with stable, well managed chronic heart failure (CHF) to discover their experiences of air travel. METHODS: An expert panel including a cardiologist, an exercise scientist, an... Read More about Experiences of air travel in patients with chronic heart failure.

 Telehealth – future directions in cardiovascular care (2010)
Journal Article
Cleland, J., & Barrett, D. (2010).  Telehealth – future directions in cardiovascular care. European cardiology review, 6(3), 30 - 32. https://doi.org/10.15420/ecr.2010.6.3.30

Over recent years, telehealth has increasingly demonstrated its value in supporting the delivery of cardiovascular healthcare. From teletriage services as a portal into healthcare through to telemonitoring of heart failure patients, technology is alr... Read More about  Telehealth – future directions in cardiovascular care.

Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure (2010)
Journal Article
Shelton, R. J., Ingle, L., Rigby, A. S., Witte, K. K., Cleland, J. G., & Clark, A. L. (2010). Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure. European journal of heart failure, 12(9), 983-989. https://doi.org/10.1093/eurjhf/hfq086

Aims
Mechanisms of exercise limitation in patients with chronic heart failure (CHF) are incompletely understood. During matched submaximal, fixed-rate exercise, oxygen uptake is similar in patients and healthy controls. However, the importance of ca... Read More about Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure.

Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review (2010)
Journal Article
Johnson, M. J., Oxberry, S. G., Cleland, J. G., & Clark, A. L. (2010). Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review. European journal of heart failure, 12(2), 137-147. https://doi.org/10.1093/eurjhf/hfp194

AIMS: Chronic breathlessness is a major symptom for patients with compensated chronic heart failure (CHF) and its impact is different to the breathlessness resulting from pulmonary oedema. This systematic review aims to establish which tools have bee... Read More about Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review.

Lack of diastolic reserve in patients with heart failure and normal ejection fraction (2009)
Journal Article
Chattopadhyay, S., Alamgir, M. F., Nikitin, N. P., Rigby, A. S., Clark, A. L., & Cleland, J. G. F. (2010). Lack of diastolic reserve in patients with heart failure and normal ejection fraction. Circulation. Heart failure, 3(1), 35-43. https://doi.org/10.1161/CIRCHEARTFAILURE.108.824888

Background-The genesis of symptoms in patients with heart failure (HF) and normal ejection fraction (HFNEF) is unclear. Most investigations of HFNEF have focused on cardiac function at rest although most of these patients are breathless only on exerc... Read More about Lack of diastolic reserve in patients with heart failure and normal ejection fraction.

Derivation and validation of a simple clinical risk-model in heart failure based on 6 minute walk test performance and NT-proBNP status - Do we need specificity for sex and beta-blockers? (2009)
Journal Article
Frankenstein, L., Goode, K., Ingle, L., Remppis, A., Schellberg, D., Nelles, M., Katus, H. A., Clark, A. L., Cleland, J. G. F., & Zugck, C. (2011). Derivation and validation of a simple clinical risk-model in heart failure based on 6 minute walk test performance and NT-proBNP status - Do we need specificity for sex and beta-blockers?. International journal of cardiology, 147(1), 74-78. https://doi.org/10.1016/j.ijcard.2009.08.005

BACKGROUND It is unclear whether risk prediction strategies in chronic heart failure (CHF) need to be specific for sex or beta-blockers. We examined this problem and developed and validated the consequent risk models based on 6-minute-walk-test and N... Read More about Derivation and validation of a simple clinical risk-model in heart failure based on 6 minute walk test performance and NT-proBNP status - Do we need specificity for sex and beta-blockers?.

Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure (2009)
Journal Article
Ingle, L., Isted, A., Witte, K. K., Cleland, J. G., & Clark, A. L. (2009). Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure. European journal of cardiovascular prevention and rehabilitation, 16(4), 451-456. https://doi.org/10.1097/HJR.0b013e32832a4f54

INTRODUCTION: Exertional oscillatory ventilation (EOV) occurs in many patients with chronic heart failure. Two different definitions of EOV have been proposed by Corrá and Leite. We aimed to compare the prevalence of EOV and its prognostic significan... Read More about Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure.

Self-rated health and mortality in patients with chronic heart failure (2009)
Journal Article
Farkas, J., Nabb, S., Zaletel-Kragelj, L., Cleland, J. G. F., & Lainscak, M. (2009). Self-rated health and mortality in patients with chronic heart failure. European journal of heart failure, 11(5), 518-524. https://doi.org/10.1093/eurjhf/hfp038

AimsIn patients with chronic heart failure (CHF), there is limited information on self-rated health (SRH). We aimed to examine the distribution of SRH and whether SRH is associated with mortality in patients with stable CHF.Methods and resultsWe enro... Read More about Self-rated health and mortality in patients with chronic heart failure.

The prognostic value of individual NT-proBNP values in chronic heart failure does not change with advancing age (2009)
Journal Article
Frankenstein, L., Clark, A. L., Goode, K., Ingle, L., Remppis, A., Schellberg, D., Grabs, F., Nelles, M., Cleland, J. G. F., Katus, H. A., & Zugck, C. (2009). The prognostic value of individual NT-proBNP values in chronic heart failure does not change with advancing age. Heart, 95(10), 825-829. https://doi.org/10.1136/hrt.2008.158626

Background: It is unclear whether age-related increases in N-terminal pro-brain natriuretic peptide (NT-proBNP) represent a normal physiological process - possibly affecting the prognostic power - of NT-proBNP - or reflect age-related subclinical pat... Read More about The prognostic value of individual NT-proBNP values in chronic heart failure does not change with advancing age.

Predictors of short term mortality in heart failure - insights from the Euro Heart Failure survey (2008)
Journal Article
Velavan, P., Khan, N. K., Goode, K., Rigby, A. S., Loh, P. H., Komajda, M., Follath, F., Swedberg, K., Madeira, H., & Cleland, J. G. (2010). Predictors of short term mortality in heart failure - insights from the Euro Heart Failure survey. International journal of cardiology, 138(1), 63-69. https://doi.org/10.1016/j.ijcard.2008.08.004

Objective: To identify factors associated with short term mortality in hospitalised patients with heart failure. Background: Hospitalisation is frequent in patients with heart failure and is associated with a high mortality. Methods: The Euro Heart F... Read More about Predictors of short term mortality in heart failure - insights from the Euro Heart Failure survey.

Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure" (2008)
Journal Article
Ingle, L., Cleland, J. G., & Clark, A. L. (2008). Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure". Heart, 94(6), 748-753. https://doi.org/10.1136/hrt.2007.131144

Background: Epidemiological studies suggest that "diastolic heart failure" (DHF) is common and has a prognosis similar to that of systolic heart failure (SHF). We wanted to assess whether patients with breathlessness who were being treated for DHF ha... Read More about Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure".

Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure (2008)
Journal Article
Ingle, L., Witte, K. K., Cleland, J. G. F., & Clark, A. L. (2008). Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure. European journal of heart failure, 10(1), 85-88. https://doi.org/10.1016/j.ejheart.2007.10.010

Background: A low peak oxygen uptake (pV(O2)) and steep V-E/V-CO2 slope are independently associated with a worse prognosis in patients with chronic heart failure (CHF). We wished to confirm whether combining these variables as a ratio would lead to... Read More about Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure.

Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure'' (2007)
Journal Article
Ingle, L., Cleland, J. G. F., & Clark, A. L. (2008). Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure''. Heart, 94(6), 748-753. https://doi.org/10.1136/hrt.2007.131144

Background: Epidemiological studies suggest that "diastolic heart failure'' (DHF) is common and has a prognosis similar to that of systolic heart failure (SHF). We wanted to assess whether patients with breathlessness who were being treated for DHF h... Read More about Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure''.

The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of < 1.0 in patients with chronic heart failure (2007)
Journal Article
Ingle, L., Witte, K. K., Cleland, J. G., & Clark, A. L. (2008). The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of < 1.0 in patients with chronic heart failure. International journal of cardiology, 127(1), 88-92. https://doi.org/10.1016/j.ijcard.2007.04.075

Background: Peak oxygen consumption derived from a maximal cardiopulmonary exercise test (CPET) is a standard prognostic indicator in patients with chronic heart failure (CHF). Tests with a peak respiratory exchange ratio (pRER) < 1.0 are often tak... Read More about The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of < 1.0 in patients with chronic heart failure.

Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy (2007)
Journal Article
Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., Cleland, J. G., & Clark, A. L. (2007). Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy. Experimental and Clinical Cardiology, 12(1), 46-47

Background: Increasing body mass index, cholesterol and body fat are associated with a better prognosis in patients with left ventricular systolic dysfunction (LVSD). Beta-blocker usage is associated with changes in body composition and increased bod... Read More about Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy.

Cardiorespiratory requirements of the 6-min walk test in older patients with left ventricular systolic dysfunction and no major structural heart disease (2007)
Journal Article
Ingle, L., Wilkinson, M., Carroll, S., Boyes, C., Butterly, R., King, R., Cooke, C., Cleland, J., & Clark, A. (2007). Cardiorespiratory requirements of the 6-min walk test in older patients with left ventricular systolic dysfunction and no major structural heart disease. International journal of sports medicine, 28(8), 678-684. https://doi.org/10.1055/s-2007-964886

The six-minute walk test (6-MWT) is widely used to assess functional status in patients with chronic heart failure (CHF). The aims of the present study were: (1) to compare metabolic gas exchange during the 6-MWT in older patients with left ventricul... Read More about Cardiorespiratory requirements of the 6-min walk test in older patients with left ventricular systolic dysfunction and no major structural heart disease.

Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure (2007)
Journal Article
Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., Cleland, J. G., & Clark, A. L. (2007). Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure. European Heart Journal, 28(5), 560-568. https://doi.org/10.1093/eurheartj/ehl527

Background: The 6 min walk test (6-MWT) is a simple and popular test for evaluating functional status in patients with chronic heart failure (CHF). However, the prognostic value of the 6-MWT in a large, representative sample of CHF patients, and in p... Read More about Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure.

Prognostic value of the VE/VCO2 slope calculated from different time intervals in patients with suspected heart failure (2006)
Journal Article
Ingle, L., Goode, K., Carroll, S., Sloan, R., Boyes, C., Cleland, J. G., & Clark, A. L. (2007). Prognostic value of the VE/VCO2 slope calculated from different time intervals in patients with suspected heart failure. International journal of cardiology, 118(3), 350-355. https://doi.org/10.1016/j.ijcard.2006.07.105

Background: Maximal exercises testing, whether involving cycling- or walking-based protocols, are often not well tolerated in patients with chronic heart failure (CHF). The peak oxygen consumption and the slope of the relation between ventilation (V... Read More about Prognostic value of the VE/VCO2 slope calculated from different time intervals in patients with suspected heart failure.