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64Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist (2019)
Journal Article
Cawthorne, C. J., Hubin, T. J., Thompson, J. A., Clemente, G. S., Lee, R. E., Miranda, C. S., …Archibald, S. J. (2020). 64Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist. Journal of nuclear medicine, 61(1), 123-128. https://doi.org/10.2967/jnumed.118.218008

© 2020 by the Society of Nuclear Medicine and Molecular Imaging. Expression of the chemokine receptor chemokine C-X-C motif receptor 4 (CXCR4) plays an important role in cancer metastasis, in autoimmune diseases, and during stem cell-based repair pro... Read More about 64Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist.

Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells (2016)
Journal Article
Nigam, S., Burke, B. P., Davies, L. H., Domarkas, J., Wallis, J. F., Waddell, P. G., …Archibald, S. J. (2016). Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells. Chemical communications : Chem comm / the Royal Society of Chemistry, 52(44), 7114-7117. https://doi.org/10.1039/c5cc08325g

The structural features required for mitochondrial uptake of BODIPY-based optical imaging agents have been explored. The first derivatives of this class of dyes shown to have mitochondrial membrane potential-dependent uptake in both cancer and heart... Read More about Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells.

Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin (2015)
Journal Article
Entract, G. M., Bryden, F., Domarkas, J., Savoie, H., Allott, L., Archibald, S. J., …Boyle, R. W. (2015). Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin. Molecular pharmaceutics, 12(12), 4414-4423. https://doi.org/10.1021/acs.molpharmaceut.5b00606

Synthesis of the first water-soluble porphyrin radiolabeled with fluorine-18 is described: a new molecular theranostic agent which integrates the therapeutic selectivity of photodynamic therapy (PDT) with the imaging efficacy of positron emission tom... Read More about Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin.

Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions (2015)
Journal Article
Burke, B. P., Baghdadi, N., Kownacka, A. E., Nigam, S., Clemente, G. S., Al-Yassiry, M. M., …Archibald, S. J. (2015). Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions. Nanoscale, 7(36), 14889-14896. https://doi.org/10.1039/c5nr02753e

The commercial availability of combined magnetic resonance imaging (MRI)/positron emission tomography (PET) scanners for clinical use has increased demand for easily prepared agents which offer signal or contrast in both modalities. Herein we describ... Read More about Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions.


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