All Outputs (148)

Multimodal prehabilitation in people awaiting acute inpatient cardiac surgery: Study protocol for a pilot feasibility trial (PreP-ACe) (2025)
Journal Article
Raut, S., Hales, A., Twiddy, M., Dixon, L., Ngaage, D., Yates, D., Danjoux, G., & Ingle, L. (2025). Multimodal prehabilitation in people awaiting acute inpatient cardiac surgery: Study protocol for a pilot feasibility trial (PreP-ACe). PLoS ONE, 20(3 March), Article e0307341. https://doi.org/10.1371/journal.pone.0307341

Background The concept of “prehabilitation,” or optimising individual physical and mental wellbeing prior to surgery is well established in cancer and orthopaedic populations. However, amongst the cardiac surgery population, the concept is relatively... Read More about Multimodal prehabilitation in people awaiting acute inpatient cardiac surgery: Study protocol for a pilot feasibility trial (PreP-ACe).

Optimisation of the preparation phase for orthopaedic surgery: Study protocol for a student-led multimodal prehabilitation feasibility trial (BoneFit) (2025)
Journal Article
Ingle, L., Snook, J., Smith, L., Oliver, B., Bray, J., Wells, L., Moorhouse, J., Dixon, L., Simpson, P., Osman, S., Saxton, J., Rajendran, A., Gopalakrishnan, G., & Symes, T. (2025). Optimisation of the preparation phase for orthopaedic surgery: Study protocol for a student-led multimodal prehabilitation feasibility trial (BoneFit). PLoS ONE, 20(2 February), Article e0314680. https://doi.org/10.1371/journal.pone.0314680

Background Since the Covid-19 pandemic, a surgical backlog for total hip replacement (THR) and total knee replacement (TKR) surgery remains in the United Kingdom. Multimodal prehabilitation pathways (encompassing exercise, nutritional support and psy... Read More about Optimisation of the preparation phase for orthopaedic surgery: Study protocol for a student-led multimodal prehabilitation feasibility trial (BoneFit).

The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing (2024)
Journal Article
Nickolay, T., Ingle, L., Hoye, A., Garrett, A. T., & Gleadall-Siddall, D. O. (2025). The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing. Science & Sports, 40(3), 239-247. https://doi.org/10.1016/j.scispo.2024.10.003

Objectives: This study aimed to assess the relative and absolute reliability (agreement) of various parameters derived from the oxygen pulse ( O˙2Pulse) curve during cardiopulmonary exercise testing (CPET), a tool critical for evaluating cardiopulmon... Read More about The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing.

The prognostic value of simple frailty and malnutrition screening tools for determining surgical risk in patients with chronic limb threatening ischaemia undergoing major vascular surgery: A retrospective cross-sectional study (2024)
Journal Article
Palmer, J., Pymer, S., Smith, G., Ingle, L., Harwood, A., & Chetter, I. (online). The prognostic value of simple frailty and malnutrition screening tools for determining surgical risk in patients with chronic limb threatening ischaemia undergoing major vascular surgery: A retrospective cross-sectional study. Journal of Vascular Societies Great Britain and Ireland, https://doi.org/10.54522/jvsgbi.2024.124

Background: This study aims to explore the prognostic value of simple frailty and malnutrition tools for determining postoperative outcomes at 30 days and 1 year in patients with CLTI undergoing major surgery.
Methods: This was a single-centre retr... Read More about The prognostic value of simple frailty and malnutrition screening tools for determining surgical risk in patients with chronic limb threatening ischaemia undergoing major vascular surgery: A retrospective cross-sectional study.

Home-based high intensity interval training in patients with intermittent claudication: a systematic review protocol (2024)
Journal Article
Prosser, J., Staniland, T., Harwood, A., Ravindhran, B., McGregor, G., Huang, C., Twiddy, M., Nicholls, A., Ingle, L., Long, J., Chetter, I., & Pymer, S. (2024). Home-based high intensity interval training in patients with intermittent claudication: a systematic review protocol. Journal of Vascular Societies Great Britain and Ireland, 3(3), 155-159. https://doi.org/10.54522/jvsgbi.2024.103

Introduction: The aim of this systematic review is to consider the evidence base for home-based high intensity interval training (HIIT) in patients with intermittent claudication (IC). Prior knowledge of the evidence base suggests that there may be l... Read More about Home-based high intensity interval training in patients with intermittent claudication: a systematic review protocol.

Health and lifestyle advisors in support of primary care: An evaluation of an innovative pilot service in a region of high health inequality (2024)
Journal Article
Ingle, L., Martindale, R., Salami, B., Fakorede, F. I., Harvey, K., Capes, S., Abt, G., & Chipperfield, S. (2024). Health and lifestyle advisors in support of primary care: An evaluation of an innovative pilot service in a region of high health inequality. PLoS ONE, 19(4 April), Article e0298955. https://doi.org/10.1371/journal.pone.0298955

Introduction A health and lifestyle advisor service embedded within primary care was piloted in Kingston-upon-Hull from January 2021. We aimed to evaluate the first two years of service delivery by identifying patient demographics referred to the ser... Read More about Health and lifestyle advisors in support of primary care: An evaluation of an innovative pilot service in a region of high health inequality.

Effects of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People With Coronary Artery Disease: Insights From the HIIT or MISS UK Trial (2024)
Journal Article
Ingle, L., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., Banerjee, P., Shave, R., & McGregor, G. (2024). Effects of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People With Coronary Artery Disease: Insights From the HIIT or MISS UK Trial. Archives of physical medicine and rehabilitation, https://doi.org/10.1016/j.apmr.2024.03.002

Objective: To compare the characteristics of responders and nonresponders to 8 weeks of exercise training to determine differences in key cardiovascular disease outcomes in people with coronary artery disease (CAD). Design: Secondary analysis of data... Read More about Effects of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People With Coronary Artery Disease: Insights From the HIIT or MISS UK Trial.

Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology (2024)
Journal Article
Nickolay, T., McGregor, G., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., Banerjee, P., Shave, R., Metcalfe, J., Hoye, A., & Ingle, L. (2024). Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology. PLoS ONE, 19(3 March), Article e0299486. https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology.

High INtensity Interval Training in pATiEnts with Intermittent Claudication: A Qualitative Acceptability Study (2024)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Nicholls, A., Ingle, L., Long, J., Rooms, M., Chetter, I. C., & Twiddy, M. (2024). High INtensity Interval Training in pATiEnts with Intermittent Claudication: A Qualitative Acceptability Study. Annals of vascular surgery, 102, 17-24. https://doi.org/10.1016/j.avsg.2023.11.043

Background: A novel high-intensity interval training (HIIT) program has demonstrated feasibility for patients with intermittent claudication (IC). The aim of this study was to explore patient perspectives of the HIIT program to inform refinement and... Read More about High INtensity Interval Training in pATiEnts with Intermittent Claudication: A Qualitative Acceptability Study.

The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease (2024)
Thesis
Nickolay, T. The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4659878

This thesis investigates the utility of cardiopulmonary exercise testing (CPET) in assessing and managing patients with coronary artery disease (CAD), particularly focusing on the significance of oxygen pulse (O2Pulse) inflections as a marker for myo... Read More about The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease.

High-intensity interval training in patients with intermittent claudication (2023)
Presentation / Conference Contribution
Pymer, S., Harwood, A. E., Prosser, J., Waddell, A., Rhavindhran, B., McGregor, G., Ibeggazene, S., Huang, C., Twiddy, M., Nicholls, A. R., Ingle, L., Carroll, S., He, H., Long, J., Rooms, M., & Chetter, I. C. High-intensity interval training in patients with intermittent claudication. Presented at 2022 Vascular Society of Great Britain and Ireland Annual Scientific Meeting, Brighton, UK

Objective: Provision, uptake, adherence, and completion rates for supervised exercise programs (SEP) for intermittent claudication (IC) are low. A shorter, more time-efficient, 6-week, high-intensity interval training (HIIT) program may be an effecti... Read More about High-intensity interval training in patients with intermittent claudication.

Cost-effectiveness of High-Intensity Interval Training (HIIT) vs Moderate Intensity Steady-State (MISS) Training in UK Cardiac Rehabilitation (2023)
Journal Article
Albustami, M., Hartfiel, N., McGregor, G., Charles, J. M., Powell, R., Begg, B., Birkett, S. T., Nichols, S., Ennis, S., Hee, S. W., Banerjee, P., Ingle, L., Shave, R., & Edwards, R. T. (2024). Cost-effectiveness of High-Intensity Interval Training (HIIT) vs Moderate Intensity Steady-State (MISS) Training in UK Cardiac Rehabilitation. Archives of physical medicine and rehabilitation, 105(4), 639-646. https://doi.org/10.1016/j.apmr.2023.09.005

Objective: To perform a cost-effectiveness analysis of high-intensity interval training (HIIT) compared with moderate intensity steady-state (MISS) training in people with coronary artery disease (CAD) attending cardiac rehabilitation (CR). Design: S... Read More about Cost-effectiveness of High-Intensity Interval Training (HIIT) vs Moderate Intensity Steady-State (MISS) Training in UK Cardiac Rehabilitation.

A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER) (2023)
Journal Article
Ngaage, D., Mitchell, N., Dean, A., Mitchell, A., Hinde, S., Akowuah, E., Doherty, P., Nichols, S., Fairhurst, C., Flemming, K., Hewitt, C., Ingle, L., & Watson, J. (2023). A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER). Pilot and Feasibility Studies, 9(1), Article 79. https://doi.org/10.1186/s40814-023-01304-3

Objective: To determine the acceptability and feasibility of delivering early outpatient review following cardiac surgery and early cardiac rehabilitation (CR), compared to standard practice to establish if a future large-scale trial is achievable. M... Read More about A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER).

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study (2023)
Journal Article
James, E., Goodall, S., Nichols, S., Walker, K., Carroll, S., O’Doherty, A. F., & Ingle, L. (2023). Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study. Frontiers in Medicine, 10, Article 1094733. https://doi.org/10.3389/fmed.2023.1094733

Background: Low muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition, and neural decline might contribute to low muscle... Read More about Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study.

High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial (2023)
Journal Article
McGregor, G., Powell, R., Begg, B., Birkett, S. T., Nichols, S., Ennis, S., McGuire, S., Prosser, J., Fiassam, O., Hee, S. W., Hamborg, T., Banerjee, P., Hartfiel, N., Charles, J. M., Edwards, R. T., Drane, A., Ali, D., Osman, F., He, H., Lachlan, T., …Shave, R. (2023). High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial. European Journal of Preventive Cardiology, 30(9), 745-755. https://doi.org/10.1093/eurjpc/zwad039

BACKGROUND: There is a lack of international consensus regarding the prescription of high-intensity interval training (HIIT) for people with coronary artery disease (CAD) attending cardiac rehabilitation (CR). AIMS: To assess the clinical effectivene... Read More about High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial.

Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial (2022)
Journal Article
Birkett, S., Sinclair, J., Seed, S., Pymer, S., Caldow, E., Ingle, L., Harwood, A., & Egun, A. (2022). Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial. Therapeutic Advances in Cardiovascular Disease, 16, https://doi.org/10.1177/17539447221108817

Background: Peripheral artery disease affects over 236 million people globally and the classic symptom is intermittent claudication (IC) which is associated with reduction in physical activity. The evidence that supervised exercise programmes (SEPs)... Read More about Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial.

Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer (2022)
Journal Article
Ingle, L., Ruilova, S., Cui, Y., DeClercq, V., Sweeney, E., Yu, Z. M., & Forbes, C. C. (2022). Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer. Cancer Causes and Control, https://doi.org/10.1007/s10552-022-01592-9

Purpose: To determine in people with a history of cancer, whether substituting sitting time with other daily activities (i.e., sleeping, walking, moderate and vigorous physical activity) was associated with changes in waist circumference (WC), an imp... Read More about Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer.

Validity and reliability of the movement assessment battery second edition test in children with and without motor impairment: A prospective cohort study (2022)
Journal Article
Ghayour Najafabadi, M., Saghaei, B., Shariat, A., Ingle, L., Babazadeh-Zavieh, S. S., Shojaei, M., & Daneshfar, A. (2022). Validity and reliability of the movement assessment battery second edition test in children with and without motor impairment: A prospective cohort study. Annals of Medicine and Surgery, 77, Article 103672. https://doi.org/10.1016/j.amsu.2022.103672

Background: Examining the reliability and validity of the second edition movement assessment battery test (MABC-2) in children with and without motor impairment. Materials and methods: In this prospective cohort study, the MABC-2 test and development... Read More about Validity and reliability of the movement assessment battery second edition test in children with and without motor impairment: A prospective cohort study.

A pilot study examining the safety and effectiveness of 8-weeks of early cardiac rehabilitation on physical function and psychological well-being in patients following aortic root replacement (2022)
Journal Article
Najafabadi, M., Niazi, S., Mortazavian, S., Khah, A., & Ingle, L. (2022). A pilot study examining the safety and effectiveness of 8-weeks of early cardiac rehabilitation on physical function and psychological well-being in patients following aortic root replacement. Physiotherapy Practice and Research, 43(1), 37-43. https://doi.org/10.3233/PPR-210541

AIM: To determine the effects of a structured, moderate-intensity, early cardiac rehabilitation (CR) program on physical function and psychological wellbeing in patients following aortic root replacement. MATERIALS AND METHODS: Patients were randomly... Read More about A pilot study examining the safety and effectiveness of 8-weeks of early cardiac rehabilitation on physical function and psychological well-being in patients following aortic root replacement.

Effects of aquatic therapy on balance in older adults: a systematic review and meta-analysis (2021)
Journal Article
Shariat, A., Ghayour Najafabadi, M., Ghannadi, S., Nakhostin-Ansari, A., Hakakzadeh, A., Shaw, B. S., Ingle, L., & Cleland, J. A. (2021). Effects of aquatic therapy on balance in older adults: a systematic review and meta-analysis. European Geriatric Medicine, https://doi.org/10.1007/s41999-021-00577-2

Purpose: Balance is a key component of movement for daily activities, especially in older adults. Previous studies examining aquatic therapy as an effective way for improving balance have yielded inconsistent findings. The current systematic review a... Read More about Effects of aquatic therapy on balance in older adults: a systematic review and meta-analysis.