All Outputs (103)

Involving Patients and the Public in Cancer Associated Thrombosis Research: a strategy for success. (2024)
Journal Article
Edwards, M., Seddon, K., Baddeley, E., Ording, A. G., Pearson, M., Mahe, I., Mooijaart, S., Klok, F. A., Noble, S. I., & on behalf of the SERENITY consortium. (2025). Involving Patients and the Public in Cancer Associated Thrombosis Research: a strategy for success. Thrombosis journal, 18, Article 100196. https://doi.org/10.1016/j.tru.2024.100196

The role of public involvement (PI) in biomedical research has never been greater, with accumulating evidence demonstrating its ability to improve the quality of research and the likelihood of translating findings into clinical practice. As the deman... Read More about Involving Patients and the Public in Cancer Associated Thrombosis Research: a strategy for success..

Midwifery-led antenatal pelvic floor muscle exercise intervention to reduce postnatal urinary incontinence: APPEAL research programme including a feasibility and pilot cluster RCT (2024)
Journal Article
Macarthur, C., Bick, D., Salmon, V., Jones, E., Hay-Smith, J., Bishop, J., Gkini, E., Hemming, K., Webb, S., Pearson, M., Coleman, T., Terry, R., Edwards, L., Frawley, H., Oborn, E., & Dean, S. (2024). Midwifery-led antenatal pelvic floor muscle exercise intervention to reduce postnatal urinary incontinence: APPEAL research programme including a feasibility and pilot cluster RCT. Programme Grants for Applied Research, 12(9), https://doi.org/10.3310/TJDH7946

Background: Antenatal pelvic floor muscle exercises are effective in reducing postnatal urinary incontinence. Midwives, however, lack training and confidence to promote these exercises and often do not provide information or support to women to do th... Read More about Midwifery-led antenatal pelvic floor muscle exercise intervention to reduce postnatal urinary incontinence: APPEAL research programme including a feasibility and pilot cluster RCT.

Understanding European patterns of deprescribing antithrombotic medication during end-of-life care in patients with cancer (2024)
Journal Article
Martens, E. S., Becker, D., Abele, C., Abbel, D., Achterberg, W. P., Bax, J. J., Bertoletti, L., Edwards, M. E., Font, C., Gava, A., Goedegebuur, J., Højen, A. A., Huisman, M. V., Kruip, M. J., Mahé, I., Mooijaart, S. P., Pearson, M., Seddon, K., Szmit, S., Noble, S. I., …Konstantinides, S. V. (2025). Understanding European patterns of deprescribing antithrombotic medication during end-of-life care in patients with cancer. Thrombosis Research, 245, Article 109205. https://doi.org/10.1016/j.thromres.2024.109205

Background: Even though antithrombotic therapy (ATT) probably has little or even negative effect on the well-being of patients with cancer near the end of life, it is often continued until death, possibly leading to excess bleeding complications, inc... Read More about Understanding European patterns of deprescribing antithrombotic medication during end-of-life care in patients with cancer.

Implementing palliative care in the intensive care unit: a systematic review and mapping of knowledge to the implementation research logic model (2024)
Journal Article
Meddick‐Dyson, S. A., Boland, J. W., Pearson, M., Greenley, S., Gambe, R., Budding, J. R., & Murtagh, F. E. (online). Implementing palliative care in the intensive care unit: a systematic review and mapping of knowledge to the implementation research logic model. Intensive care medicine, https://doi.org/10.1007/s00134-024-07623-0

Purpose: The importance and effectiveness of palliative care (PC) in intensive care units (ICU) are known. Less is known about the implementation and integration of ICU-based PC interventions. This systematic review aims to use a modified implementat... Read More about Implementing palliative care in the intensive care unit: a systematic review and mapping of knowledge to the implementation research logic model.

Why do acute healthcare staff behave unprofessionally towards each other and how can these behaviours be reduced? A realist review (2024)
Journal Article
Aunger, J. A., Abrams, R., Westbrook, J. I., Wright, J. M., Pearson, M., Jones, A., Mannion, R., & Maben, J. (2024). Why do acute healthcare staff behave unprofessionally towards each other and how can these behaviours be reduced? A realist review. Health and Social Care Delivery Research, 12(25), https://doi.org/10.3310/PAMV3758

Background: Unprofessional behaviour in healthcare systems can negatively impact staff well-being, patient safety and organisational costs. Unprofessional behaviour encompasses a range of behaviours, including incivility, microaggressions, harassment... Read More about Why do acute healthcare staff behave unprofessionally towards each other and how can these behaviours be reduced? A realist review.

How can interventions more directly address drivers of unprofessional behaviour between healthcare staff? (2024)
Journal Article
Aunger, J. A., Abrams, R., Mannion, R., Westbrook, J. I., Jones, A., Wright, J. M., Pearson, M., & Maben, J. (2024). How can interventions more directly address drivers of unprofessional behaviour between healthcare staff?. BMJ Open Quality, 13(3), Article e002830. https://doi.org/10.1136/bmjoq-2024-002830

Unprofessional behaviours (UBs) between healthcare staff are widespread and have negative impacts on patient safety, staff well-being and organisational efficiency. However, knowledge of how to address UBs is lacking. Our recent realist review analys... Read More about How can interventions more directly address drivers of unprofessional behaviour between healthcare staff?.

Driving quality in delirium care through a patient-centered monitoring system in palliative care: Protocol for the two-staged exploratory sequential mixed methods MODEL-PC study (2024)
Journal Article
van Oosterom, N., Agar, M. R., Walpole, G., Casey, P., Moffat, P., Bradley, K., Cook, A., Johnson, C., Chye, R., Oehme, J., Senatore, M., Virdun, C., Pearson, M., Featherstone, I., Lawlor, P. G., Bush, S. H., Daveson, B., Clapham, S., Campbell, K., & Hosie, A. (2024). Driving quality in delirium care through a patient-centered monitoring system in palliative care: Protocol for the two-staged exploratory sequential mixed methods MODEL-PC study. Delirium Communications, https://doi.org/10.56392/001c.94808

Introduction
Delirium is a serious acute neurocognitive condition that is common in palliative care units and yet under-addressed. To improve delirium care in this setting, we will develop and pilot a monitoring system that integrates the Delirium C... Read More about Driving quality in delirium care through a patient-centered monitoring system in palliative care: Protocol for the two-staged exploratory sequential mixed methods MODEL-PC study.

Developing a typology of interventions to support doctors’ mental health and wellbeing (2024)
Journal Article
Pearson, A., Carrieri, D., Melvin, A., Bramwell, C., Scott, J., Hancock, J., Papoutsi, C., Pearson, M., Wong, G., & Mattick, K. (2024). Developing a typology of interventions to support doctors’ mental health and wellbeing. BMC health services research, 24(1), Article 573. https://doi.org/10.1186/s12913-024-10884-6

Background: The problem of mental ill-health in doctors is complex, accentuated by the COVID-19 pandemic, and impacts on healthcare provision and broader organisational performance. There are many interventions to address the problem but currently no... Read More about Developing a typology of interventions to support doctors’ mental health and wellbeing.

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): Feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care (2024)
Journal Article
Jackson, G. P., Jackson, C., Boland, J. W., Featherstone, I., Huang, C., Ogden, M., Sartain, K., Siddiqi, N., Twiddy, M., Pearson, M., & Johnson, M. J. (2024). Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): Feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care. Palliative medicine, 38(4), 447-456. https://doi.org/10.1177/02692163241236325

Background: Delirium is a complex condition, stressful for all involved. Although highly prevalent in palliative care settings, it remains underdiagnosed and associated with poor outcomes. Guideline-adherent delirium care may improve its detection, a... Read More about Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): Feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care.

Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making (2024)
Journal Article
Bravington, A., Boland, J. W., Greenley, S., Lind, M., Murtagh, F. E., Patterson, M., Pearson, M., & Johnson, M. J. (2024). Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making. PLoS ONE, 19(1 January), Article e0294218. https://doi.org/10.1371/journal.pone.0294218

Introduction Malignant bowel obstruction is a distressing complication of cancer, causing pain, nausea and vomiting, and often has a poor prognosis. Severe and rapidly developing symptoms, a lack of robust clinical guidelines and the need for multidi... Read More about Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making.

Developing a strategy to scale up place-based arts initiatives that support mental health and wellbeing: A realist evaluation of ‘Arts for the Blues’ (2024)
Journal Article
Karkou, V., Omylinska-Thurston, J., Thurston, S., Clark, R., Perris, E., Kaehne, A., & Pearson, M. (2024). Developing a strategy to scale up place-based arts initiatives that support mental health and wellbeing: A realist evaluation of ‘Arts for the Blues’. PLoS ONE, 19(1), Article e0296178. https://doi.org/10.1371/journal.pone.0296178

Place-based arts initiatives are regarded as rooted in local need and as having capacity to engage local assets. However, many place-based arts initiatives remain poorly funded and short-lived, receiving little attention on how to scale up and sustai... Read More about Developing a strategy to scale up place-based arts initiatives that support mental health and wellbeing: A realist evaluation of ‘Arts for the Blues’.

Erratum: Correction: Supported: Supporting, enabling, and sustaining homecare workers to deliver end-of-life care: A qualitative study protocol (PloS one (2023) 18 12 (e0291525)) (2024)
Journal Article
Bayley, Z., Bothma, J., Bravington, A., Forward, C., Hussain, J., Manthorpe, J., Pearson, M., Roberts, H., Taylor, P., Walker, L., White, C., Wray, J., & Johnson, M. J. (2024). Erratum: Correction: Supported: Supporting, enabling, and sustaining homecare workers to deliver end-of-life care: A qualitative study protocol (PloS one (2023) 18 12 (e0291525)). PLoS ONE, 19(2), Article e0298925. https://doi.org/10.1371/journal.pone.0298925

[This corrects the article DOI: 10.1371/journal.pone.0291525.].

Supported: supporting, enabling, and sustaining homecare workers to deliver end-of-life care: a qualitative study 2 protocol 3 4 (2023)
Journal Article
Bayley, Z., Bothma, J., Bravington, A., Forward, C., Hussain, J., Manthorpe, J., Pearson, M., Roberts, H., Taylor, P., Walker, L., White, C., Wray, J., & Johnson, M. J. (2023). Supported: supporting, enabling, and sustaining homecare workers to deliver end-of-life care: a qualitative study 2 protocol 3 4. PLoS ONE, 18(12), Article e0291525. https://doi.org/10.1371/journal.pone.0291525

BACKGROUND: Homecare workers provide essential care at home for people at end-of-life but are often poorly trained and supported. AIM: To explore the experiences and needs of homecare workers and the views of homecare clients and carers, and other co... Read More about Supported: supporting, enabling, and sustaining homecare workers to deliver end-of-life care: a qualitative study 2 protocol 3 4.

Drivers of unprofessional behaviour between staff in acute care hospitals: a realist review (2023)
Journal Article
Aunger, J. A., Maben, J., Abrams, R., Wright, J. M., Mannion, R., Pearson, M., Jones, A., & Westbrook, J. I. (2023). Drivers of unprofessional behaviour between staff in acute care hospitals: a realist review. BMC health services research, 23(1), Article 1326. https://doi.org/10.1186/s12913-023-10291-3

Background: Unprofessional behaviours (UB) between healthcare staff are rife in global healthcare systems, negatively impacting staff wellbeing, patient safety and care quality. Drivers of UBs include organisational, situational, team, and leadership... Read More about Drivers of unprofessional behaviour between staff in acute care hospitals: a realist review.

The handheld fan for chronic breathlessness: Clinicians' experiences and views of implementation in clinical practice (2023)
Journal Article
Brown, J., Miller, I., Barnes-Harris, M., Johnson, M. J., Pearson, M., Luckett, T., & Swan, F. (2023). The handheld fan for chronic breathlessness: Clinicians' experiences and views of implementation in clinical practice. PLoS ONE, 18(11), Article e0294748. https://doi.org/10.1371/journal.pone.0294748

INTRODUCTION: The handheld fan ('fan') is useful for chronic breathlessness management, however little is known about clinicians' implementation of the fan in clinical practice. AIM: To explore clinicians' experiences and views of fan implementation.... Read More about The handheld fan for chronic breathlessness: Clinicians' experiences and views of implementation in clinical practice.

How can NHS trusts in England optimise strategies to improve the mental health and well-being of hospital doctors? The Care Under Pressure 3 (CUP3) realist evaluation study protocol (2023)
Journal Article
Bramwell, C., Carrieri, D., Melvin, A., Pearson, A., Scott, J., Hancock, J., Pearson, M., Papoutsi, C., Wong, G., & Mattick, K. (2023). How can NHS trusts in England optimise strategies to improve the mental health and well-being of hospital doctors? The Care Under Pressure 3 (CUP3) realist evaluation study protocol. BMJ open, 13(11), Article e073615. https://doi.org/10.1136/bmjopen-2023-073615

INTRODUCTION: The growing incidence of mental ill health in doctors was a major issue in the UK and internationally, even prior to the COVID-19 pandemic. It has significant and far-reaching implications, including poor quality or inconsistent patient... Read More about How can NHS trusts in England optimise strategies to improve the mental health and well-being of hospital doctors? The Care Under Pressure 3 (CUP3) realist evaluation study protocol.

BREATHLEssness in INDIA (BREATHE-INDIA)–Study protocol for the co-design of a community breathlessness intervention in India using realist methods and intervention mapping (2023)
Journal Article
Clark, J., Salins, N., Pearson, M., Spathis, A., Currow, D. C., Williams, S., & Johnson, M. (2023). BREATHLEssness in INDIA (BREATHE-INDIA)–Study protocol for the co-design of a community breathlessness intervention in India using realist methods and intervention mapping. PLoS ONE, 18(11 November), Article e0293918. https://doi.org/10.1371/journal.pone.0293918

Background Breathlessness that persists despite treatment of causal disease(s) is disabling, associated with high therapy-related costs and poor socioeconomic outcomes. Low resource countries bear a disproportionate burden of respiratory problems, of... Read More about BREATHLEssness in INDIA (BREATHE-INDIA)–Study protocol for the co-design of a community breathlessness intervention in India using realist methods and intervention mapping.

Interventions to address unprofessional behaviours between staff in acute care: what works for whom and why? A realist review (2023)
Journal Article
Maben, J., Aunger, J., Abrams, R., Wright, J., Pearson, M., Westbrook, J., Jones, A., & Mannion, R. (2023). Interventions to address unprofessional behaviours between staff in acute care: what works for whom and why? A realist review. BMC medicine, 21(1), Article 403. https://doi.org/10.1186/s12916-023-03102-3

Background: Unprofessional behaviour (UB) between staff encompasses various behaviours, including incivility, microaggressions, harassment, and bullying. UB is pervasive in acute healthcare settings and disproportionately impacts minoritised staff. U... Read More about Interventions to address unprofessional behaviours between staff in acute care: what works for whom and why? A realist review.

Views and experiences of opioid access amongst palliative care providers and public representatives in a low-resource setting: A qualitative interview study (2023)
Journal Article
Clark, J., Salins, N., Daniel, S., Currow, D. C., Jones, L., Pearson, M., Bunton, R., Mankel, J., Braithwaite, C., Gilchrist, M. M., & Johnson, M. J. (2023). Views and experiences of opioid access amongst palliative care providers and public representatives in a low-resource setting: A qualitative interview study. PLOS Global Public Health, 3(9), Article e0002401. https://doi.org/10.1371/journal.pgph.0002401

Opioids (e.g. morphine) are affordable, effective interventions for cancer-related pain. However, equity of access to this key medication remains a global challenge, particularly in low- and middle-income countries. We aimed to explore views of palli... Read More about Views and experiences of opioid access amongst palliative care providers and public representatives in a low-resource setting: A qualitative interview study.

The Feasibility and Acceptability of ExerciseGuide UK: A Web-Based Platform for Personalised Physical Activity Programmes and Educational Resources for Individuals Living with and Beyond Lung Cancer: A Mixed Methods Thesis (2023)
Thesis
Curry, J. The Feasibility and Acceptability of ExerciseGuide UK: A Web-Based Platform for Personalised Physical Activity Programmes and Educational Resources for Individuals Living with and Beyond Lung Cancer: A Mixed Methods Thesis. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4790527

Background: Lung cancer has a high incidence and mortality rate, particularly in older adults (65y+). Physical activity can improve the physical and psychological health of these patients. A virtual exercise and education programme could address barr... Read More about The Feasibility and Acceptability of ExerciseGuide UK: A Web-Based Platform for Personalised Physical Activity Programmes and Educational Resources for Individuals Living with and Beyond Lung Cancer: A Mixed Methods Thesis.