All Outputs (5)

Integrated DNA extraction and amplification using electrokinetic pumping in a microfluidic device (2011)
Journal Article
Parton, J., Birch, C., Kemp, C., Haswell, S. J., Pamme, N., & Shaw, K. J. (2012). Integrated DNA extraction and amplification using electrokinetic pumping in a microfluidic device. Analytical Methods, 4(1), 96-100. https://doi.org/10.1039/c1ay05552f

An integrated system employing anion exchange for the extraction of DNA from biological samples prior to polymerase chain reaction DNA amplification has been developed, based on microfluidic methodology utilising electrokinetic pumping. In this syste... Read More about Integrated DNA extraction and amplification using electrokinetic pumping in a microfluidic device.

Microfluidic platforms for performing surface-based clinical assays (2011)
Journal Article
Tarn, M. D., & Pamme, N. (2011). Microfluidic platforms for performing surface-based clinical assays. Expert review of molecular diagnostics, 11(7), 711-720. https://doi.org/10.1586/ERM.11.59

The need for fast, specific and portable diagnostic systems for clinical assays has, in recent years, led to an explosion of research into microfluidic chip-based immunoassays towards rapid point-of-care analysis. Such devices exploit small dimension... Read More about Microfluidic platforms for performing surface-based clinical assays.

On-chip pre-concentration and complexation of [18F]fluoride ions via regenerable anion exchange particles for radiochemical synthesis of Positron Emission Tomography tracers (2011)
Journal Article
De Leonardis, F., Pascali, G., Salvadori, P. A., Watts, P., & Pamme, N. (2011). On-chip pre-concentration and complexation of [18F]fluoride ions via regenerable anion exchange particles for radiochemical synthesis of Positron Emission Tomography tracers. Journal of Chromatography A, 1218(29), 4714-4719. https://doi.org/10.1016/j.chroma.2011.05.062

Microfluidic approaches have demonstrated a relevant impact on radiochemical reactions involving Positron Emission Tomography (PET) nuclides, due to shorter reaction times and smaller precursor quantities. However, little attention has been given to... Read More about On-chip pre-concentration and complexation of [18F]fluoride ions via regenerable anion exchange particles for radiochemical synthesis of Positron Emission Tomography tracers.

Cell sorting by endocytotic capacity in a microfluidic magnetophoresis device (2011)
Journal Article
Robert, D., Pamme, N., Conjeaud, H., Gazeau, F., Iles, A., & Wilhelm, C. (2011). Cell sorting by endocytotic capacity in a microfluidic magnetophoresis device. Lab on a chip, 11(11), 1902-1910. https://doi.org/10.1039/c0lc00656d

Magnetically labelled cells are finding a wealth of applications for in vitro analysis as well as in vivo treatments. Sorting of cells into subpopulations based on their magnetite loading is an important step in such procedures. Here, we study the so... Read More about Cell sorting by endocytotic capacity in a microfluidic magnetophoresis device.

Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup (2011)
Journal Article
Rodríguez-Villarreal, A. I., Tarn, M. D., Madden, L. A., Lutz, J. B., Greenman, J., Samitier, J., & Pamme, N. (2011). Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup. Lab on a chip, 11(7), 1240-1248. https://doi.org/10.1039/c0lc00464b

The continuous flow focussing and manipulation of particles and cells are important factors in microfluidic applications for performing accurate and reproducible procedures downstream. Many particle focussing methods require complex setups or channel... Read More about Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup.