All Outputs (9)

Monolith-based68Ga processing: A new strategy for purification to facilitate direct radiolabelling methods (2016)
Journal Article
He, P., Burke, B. P., Clemente, G. S., Brown, N., Pamme, N., & Archibald, S. J. (2016). Monolith-based68Ga processing: A new strategy for purification to facilitate direct radiolabelling methods. Reaction Chemistry and Engineering, 1(4), 361-365. https://doi.org/10.1039/c6re00081a

The post-processing of68Ga generator eluate by means of a novel high capacity cation-exchange silica monolith column has been validated in this work. Quantitative release of a purified68Ga solution in high concentration can be achieved using weak aci... Read More about Monolith-based68Ga processing: A new strategy for purification to facilitate direct radiolabelling methods.

Sample introduction interface for on-chip nucleic acid-based analysis of Helicobacter pylori from stool samples (2016)
Journal Article
Esfahani, M. M. N., Shaw, K. J., Esfahani, M. M., Kemp, C., Tarn, M. D., Melling, L., Kemp, C., Pamme, N., Melling, L., & Mosley, O. (2016). Sample introduction interface for on-chip nucleic acid-based analysis of Helicobacter pylori from stool samples. Lab on a chip, 16(11), 2108-2115. https://doi.org/10.1039/c6lc00228e

Despite recent advances in microfluidic-based integrated diagnostic systems, the sample introduction interface, especially with regards to large volume samples, has often been neglected. We present a sample introduction interface that allows direct o... Read More about Sample introduction interface for on-chip nucleic acid-based analysis of Helicobacter pylori from stool samples.

Magnetic particle plug-based assays for biomarker analysis (2016)
Journal Article
Phurimsak, C., Tarn, M. D., & Pamme, N. (2016). Magnetic particle plug-based assays for biomarker analysis. Micromachines, 7(5), 77. https://doi.org/10.3390/mi7050077

Conventional immunoassays offer selective and quantitative detection of a number of biomarkers, but are laborious and time-consuming. Magnetic particle-based assays allow easy and rapid selection of analytes, but still suffer from the requirement of... Read More about Magnetic particle plug-based assays for biomarker analysis.

Development of radiodetection systems towards miniaturised quality control of PET and SPECT radiopharmaceuticals (2016)
Journal Article
Taggart, M. P., Tarn, M. D., Esfahani, M. M. N., Schofield, D. M., Brown, N. J., Archibald, S. J., Deakin, T., Pamme, N., & Thompson, L. F. (2016). Development of radiodetection systems towards miniaturised quality control of PET and SPECT radiopharmaceuticals. Lab on a chip, 16(9), 1605-1616. https://doi.org/10.1039/c6lc00099a

The ability to detect radiation in microfluidic devices is important for the on-chip analysis of radiopharmaceuticals, but previously reported systems have largely suffered from various limitations including cost, complexity of fabrication, and insuf... Read More about Development of radiodetection systems towards miniaturised quality control of PET and SPECT radiopharmaceuticals.

Multiplex sorting of foodborne pathogens by on-chip free-flow magnetophoresis (2016)
Journal Article
Ngamsom, B., Esfahani, M. M., Phurimsak, C., Lopez-Martinez, M. J., Raymond, J.-C., Broyer, P., Patel, P., & Pamme, N. (2016). Multiplex sorting of foodborne pathogens by on-chip free-flow magnetophoresis. Analytica Chimica Acta, 918, 69-76. https://doi.org/10.1016/j.aca.2016.03.014

This study reports multiplex sorting of Salmonella typhimurium and Escherichia coli 0157, from broth cultures and from pathogen-spiked skinned chicken breast enrichment broths by employing microfluidic free-flow magnetophoresis. Magnetic beads of dif... Read More about Multiplex sorting of foodborne pathogens by on-chip free-flow magnetophoresis.

Positron detection in silica monoliths for miniaturised quality control of PET radiotracers (2016)
Journal Article
Tarn, M. D., Maneuski, D., Alexander, R., Brown, N. J., O’Shea, V., Pimlott, S. L., Pamme, N., & Archibald, S. J. (2016). Positron detection in silica monoliths for miniaturised quality control of PET radiotracers. Chemical communications : Chem comm / the Royal Society of Chemistry, 52(45), 7221-7224. https://doi.org/10.1039/c6cc00660d

We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [⁶⁸Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-no... Read More about Positron detection in silica monoliths for miniaturised quality control of PET radiotracers.

On-chip acoustophoretic isolation of microflora including S. typhimurium from raw chicken, beef and blood samples (2016)
Journal Article
Ngamsom, B., Lopez-Martinez, M. J., Raymond, J.-C., Broyer, P., Patel, P., & Pamme, N. (2016). On-chip acoustophoretic isolation of microflora including S. typhimurium from raw chicken, beef and blood samples. Journal of microbiological methods, 123, 79-86. https://doi.org/10.1016/j.mimet.2016.01.016

Pathogen analysis in food samples routinely involves lengthy growth-based pre-enrichment and selective enrichment of food matrices to increase the ratio of pathogen to background flora. Similarly, for blood culture analysis, pathogens must be isolate... Read More about On-chip acoustophoretic isolation of microflora including S. typhimurium from raw chicken, beef and blood samples.

Lab-on-a-chip workshop activities for secondary school students (2016)
Journal Article
Esfahani, M. M. N., Tarn, M. D., Choudhury, T. A., Hewitt, L. C., Mayo, A. J., Rubin, T. A., Waller, M. R., Christensen, M. G., Dawson, A., & Pamme, N. (2016). Lab-on-a-chip workshop activities for secondary school students. Biomicrofluidics, 10(1), Article 011301. https://doi.org/10.1063/1.4940884

The ability to engage and inspire younger generations in novel areas of science is important for bringing new researchers into a burgeoning field, such as lab-on-a-chip. We recently held a lab-on-a-chip workshop for secondary school students, for whi... Read More about Lab-on-a-chip workshop activities for secondary school students.

Microparticle image processing and field profile optimisation for automated Lab-On-Chip magnetophoretic analytical systems (2016)
Thesis
Chowdhury, M. M. U. (2016). Microparticle image processing and field profile optimisation for automated Lab-On-Chip magnetophoretic analytical systems. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4219336

The work described in this thesis, concerns developments to analytical microfluidic Lab-On-Chip platform originally developed by Prof Pamme's research group at the University of Hull. This work aims to move away from traditional laboratory analysis s... Read More about Microparticle image processing and field profile optimisation for automated Lab-On-Chip magnetophoretic analytical systems.