All Outputs (46)

Site-specific and stoichiometric conjugation of cationic porphyrins to antiangiogenic monoclonal antibodies (2010)
Journal Article
Alonso, C. M. A., Palumbo, A., Bullous, A. J., Pretto, F., Neri, D., & Boyle, R. W. (2010). Site-specific and stoichiometric conjugation of cationic porphyrins to antiangiogenic monoclonal antibodies. Bioconjugate chemistry, 21(2), 302-313. https://doi.org/10.1021/bc9003537

Synthesis of three new cationic thiol-reactive maleimide-porphyrin derivatives and their use in site-specific conjugation to monoclonal antibodies is reported. The selective reactivity toward thiols is demonstrated using competition experiments, wher... Read More about Site-specific and stoichiometric conjugation of cationic porphyrins to antiangiogenic monoclonal antibodies.

Synthesis and phototoxicity of polyethylene glycol (PEG) substituted metal-free and metallo-porphyrins: Effect of PEG chain length, coordinated metal, and axial ligand (2009)
Journal Article
Mewis, R. E., Savoie, H., Archibald, S. J., & Boyle, R. W. (2009). Synthesis and phototoxicity of polyethylene glycol (PEG) substituted metal-free and metallo-porphyrins: Effect of PEG chain length, coordinated metal, and axial ligand. Photodiagnosis and Photodynamic Therapy, 6(3-4), 200-206. https://doi.org/10.1016/j.pdpdt.2009.08.002

Treatment of 5,10,15,20-tetra(pentafluorophenyl) porphyrins with polyethylene glycol (PEG) halides and sodium sulfide is a mild and efficient route to water-soluble PEG substituted porphyrins. The method has been used to access a series of free-base... Read More about Synthesis and phototoxicity of polyethylene glycol (PEG) substituted metal-free and metallo-porphyrins: Effect of PEG chain length, coordinated metal, and axial ligand.

Glycerol and galactose substituted zinc phthalocyanines. Synthesis and photodynamic activity (2009)
Journal Article
Zorlu, Y., Ermeydan, M. A., Dumoulin, F., Ahsen, V., Savoie, H., & Boyle, R. W. (2009). Glycerol and galactose substituted zinc phthalocyanines. Synthesis and photodynamic activity. Photochemical & photobiological sciences : an international journal, 8(3), 312-318. https://doi.org/10.1039/b817348f

Three novel water soluble, non-ionic, zinc phthalocyanines (Pcs) have been synthesized and their spectroscopic and photodynamic properties investigated in aqueous media. One of the three compounds was shown to be significantly less aggregated, when c... Read More about Glycerol and galactose substituted zinc phthalocyanines. Synthesis and photodynamic activity.

Reductive Amination-A convenient method for generating diverse, mono-functionalised 5,10,15,20-tetraphenyl porphyrins (2009)
Journal Article
Welch, C., Archibald, S. J., & Boyle, R. (2009). Reductive Amination-A convenient method for generating diverse, mono-functionalised 5,10,15,20-tetraphenyl porphyrins. SYNTHESIS, 2009(4), 551-556. https://doi.org/10.1055/s-0028-1083335

Formylation followed by reductive amination of 5,10,15,20-tetraphenyl porphyrin (TPP) is shown to be a versatile synthetic procedure for monosubstitution of the porphyrin core re-giospecifically at one β-position. A diverse range of substituents can... Read More about Reductive Amination-A convenient method for generating diverse, mono-functionalised 5,10,15,20-tetraphenyl porphyrins.

Mesogenic dipyrrins - building blocks for the fabrication of fluorescent and metal-containing materials (2008)
Journal Article
Wilson, C. J., James, L., Mehl, G. H., & Boyle, R. W. (2008). Mesogenic dipyrrins - building blocks for the fabrication of fluorescent and metal-containing materials. Chemical communications : Chem comm / the Royal Society of Chemistry, 4582-4584. https://doi.org/10.1039/b806672h

A new class of mesogenic dipyrrins is reported and their use in the fabrication of fluorescent and metal-containing self assembling materials is demonstrated.

Thioglycosylated cationic porphyrins––convenient synthesis and photodynamic activity in vitro (2004)
Journal Article
Ahmed, S., Davoust, E., Savoie, H., Boa, A. N., & Boyle, R. W. (2004). Thioglycosylated cationic porphyrins––convenient synthesis and photodynamic activity in vitro. Tetrahedron letters; the international organ for the rapid publication of preliminary communications in organic chemistry, 45(31), 6045-6047. https://doi.org/10.1016/j.tetlet.2004.06.021

A convenient and flexible synthesis of meso-tetraaryl porphyrins substituted with three thioglycosyl units, and also bearing one pyridyl substituent is reported. Quaternisation of the pyridine nitrogen with alkyl iodides gives access to a range of wa... Read More about Thioglycosylated cationic porphyrins––convenient synthesis and photodynamic activity in vitro.