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All Outputs (173)

'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives (2020)
Journal Article
Howell, D., Hart, R., Smith, A., MacLeod, U., Patmore, R., & Roman, E. (2020). 'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives. BMJ open, 10(2), Article e034244. https://doi.org/10.1136/bmjopen-2019-034244

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. Objectives To explore alignment of experiences before lymphoma and myeloma diagnosis with the appraisal, help seeking and diagnostic intervals in the Model of Pa... Read More about 'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives.

Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014) (2020)
Journal Article
Gadoud, A., Kane, E., Oliver, S. E., Johnson, M. J., MacLeod, U., & Allgar, V. (2020). Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014). BMJ supportive & palliative care, Article 001833. https://doi.org/10.1136/bmjspcare-2019-001833

Objectives While guidelines recommend palliative care in non-cancer conditions, this has not been widely implemented. We examined whether the recording of a palliative care approach and the numbers of hospital deaths for deceased patients with heart... Read More about Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014).

What do the healthcare experiences of people with long-term conditions tell us about person-centred care? A systematic review. (2019)
Journal Article
Dell Olio, M., Pask, S., Seymour, J., & Reeve, J. (2019). What do the healthcare experiences of people with long-term conditions tell us about person-centred care? A systematic review. European journal for person centered healthcare, 7(4),

Introduction
Growing numbers of people now live with long term conditions. For each person, the challenges are multiple and unique to that individual. In recognition of this, health policy places greater emphasis on the delivery of person-centred ca... Read More about What do the healthcare experiences of people with long-term conditions tell us about person-centred care? A systematic review..

Non-attendance at urgent referral appointments for suspected cancer: A qualitative study to gain understanding from patients and GPS (2019)
Journal Article
Jefferson, L., Atkin, K., Sheridan, R., Oliver, S., Macleod, U., Hall, G., Forbes, S., Green, T., Allgar, V., & Knapp, P. (2019). Non-attendance at urgent referral appointments for suspected cancer: A qualitative study to gain understanding from patients and GPS. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(689), E850-E859. https://doi.org/10.3399/bjgp19X706625

© British Journal of General Practice
Background: The 2-week-wait urgent referral policy in the UK has sought to improve cancer outcomes by accelerating diagnosis and treatment. However, around 5-7% of symptomatic referred patients cancel or do not... Read More about Non-attendance at urgent referral appointments for suspected cancer: A qualitative study to gain understanding from patients and GPS.

Perceived colorectal cancer candidacy and the role of candidacy in colorectal cancer screening (2019)
Journal Article
Bikker, A. P., Macdonald, S., Robb, K. A., Conway, E., Browne, S., Campbell, C., Weller, D., Steele, R., & Macleod, U. (2019). Perceived colorectal cancer candidacy and the role of candidacy in colorectal cancer screening. Health, Risk and Society, 21(7-8), 352-372. https://doi.org/10.1080/13698575.2019.1680816

© 2019 Informa UK Limited, trading as Taylor & Francis Group. Screening is a well-established tool to advance earlier cancer diagnosis. We used Davison’s concept of ‘candidacy’ to explore how individuals draw on collectively constructed images of ‘... Read More about Perceived colorectal cancer candidacy and the role of candidacy in colorectal cancer screening.

Physiotherapy outcome measures of haemophilia acute bleed episodes: What matters to patients? (2019)
Journal Article
Bradshaw, E., McClellan, C., Whybrow, P., & Cramp, F. (2019). Physiotherapy outcome measures of haemophilia acute bleed episodes: What matters to patients?. Haemophilia, 25(6), 1066-1072. https://doi.org/10.1111/hae.13840

Introduction
The research was conducted at a UK teaching hospital and Haemophilia Comprehensive Care Centre (CCC) as part of a research programme investigating physiotherapy for acute bleed management.
Aim
The aim of the study was to understand th... Read More about Physiotherapy outcome measures of haemophilia acute bleed episodes: What matters to patients?.

Patient non-attendance at urgent referral appointments for suspected cancer and its links to cancer diagnosis and one year mortality: A cohort study of patients referred on the Two Week Wait pathway (2019)
Journal Article
Sheridan, R., Oliver, S. E., Hall, G., Allgar, V., Melling, P., Bolton, E., Atkin, K., Denton, D., Forbes, S., Green, T., Macleod, U., & Knapp, P. (2019). Patient non-attendance at urgent referral appointments for suspected cancer and its links to cancer diagnosis and one year mortality: A cohort study of patients referred on the Two Week Wait pathway. Cancer epidemiology, 63, Article 101588. https://doi.org/10.1016/j.canep.2019.101588

© 2019 The Authors Background: The ‘Two Week Wait’ policy aims to ensure patients with suspected cancer are seen within two weeks of referral. However, patient non-attendance can result in this target being missed. This study aimed to identify predic... Read More about Patient non-attendance at urgent referral appointments for suspected cancer and its links to cancer diagnosis and one year mortality: A cohort study of patients referred on the Two Week Wait pathway.

An integrated understanding of the complex drivers of emergency presentations and admissions in cancer patients: qualitative modelling of secondary-care health professionals’ experiences and views (2019)
Journal Article
Chen, H., Walabyeki, J., Johnson, M., Boland, E., Seymour, J., & Macleod, U. (2019). An integrated understanding of the complex drivers of emergency presentations and admissions in cancer patients: qualitative modelling of secondary-care health professionals’ experiences and views. PLoS ONE, 14(5), Article e0216430. https://doi.org/10.1371/journal.pone.0216430

The number of cancer-related emergency presentations and admissions has been steadily increasing in the UK. Drivers of this phenomenon are complex, multifactorial and interlinked. The main objective of this study was to understand the complexity of e... Read More about An integrated understanding of the complex drivers of emergency presentations and admissions in cancer patients: qualitative modelling of secondary-care health professionals’ experiences and views.

Facilitated group work for people with long-term conditions: a systematic review of benefits from studies of group-work interventions (2019)
Journal Article
Jackson, M., Jones, D., Dyson, J., & Macleod, U. (2019). Facilitated group work for people with long-term conditions: a systematic review of benefits from studies of group-work interventions. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(682), E363-E372. https://doi.org/10.3399/bjgp19X702233

Background: About 15.4 million people in the UK live with a long-term condition. Of the health and social care spend, 70% is invested in caring for this population. Evidence suggests that group-work interventions offer patient support, improved outco... Read More about Facilitated group work for people with long-term conditions: a systematic review of benefits from studies of group-work interventions.

Disease-related factors affecting timely lymphoma diagnosis: A qualitative study exploring patient experiences (2019)
Journal Article
Howell, D. A., Hart, R. I., Smith, A. G., Roman, E., Macleod, U., & Patmore, R. (2019). Disease-related factors affecting timely lymphoma diagnosis: A qualitative study exploring patient experiences. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(679), E134-E145. https://doi.org/10.3399/bjgp19X701009

© British Journal of General Practice. Background Expediting cancer diagnosis is widely perceived as one way to improve patient outcomes. Evidence indicates that lymphoma diagnosis is often delayed, yet understanding of issues influencing this is inc... Read More about Disease-related factors affecting timely lymphoma diagnosis: A qualitative study exploring patient experiences.

Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study (2019)
Journal Article
Cunningham, Y., Wyke, S., Blyth, K. G., Rigg, D., Macdonald, S., Macleod, U., Harrow, S., Robb, K. A., & Whitaker, K. L. (2019). Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study. Psycho-oncology, 28(4), 718-725. https://doi.org/10.1002/pon.5005

© 2019 The Authors. Psycho-Oncology Published by John Wiley & Sons Ltd. Objective: The incidence of lung cancer is four times higher in people with chronic obstructive pulmonary disease (COPD) compared with the general population. Promotion of a sh... Read More about Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study.

Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK (2019)
Journal Article
Allgar, V. L., Oliver, S. E., Chen, H., Oviasu, O., Johnson, M. J., & Macleod, U. (2019). Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK. Cancer epidemiology, 59, 37-45. https://doi.org/10.1016/j.canep.2019.01.008

© 2019 Elsevier Ltd Background: England has significantly higher mortality risks due to Head and Neck Cancer (HNC) compared with other European countries. Early diagnosis is important as it is likely to increase early-stage diagnosis and improve surv... Read More about Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK.

Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal? (2019)
Journal Article
Macdonald, S., Conway, E., Bikker, A., Browne, S., Robb, K., Campbell, C., Steele, R. J., Weller, D., & Macleod, U. (2019). Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal?. Social science & medicine, 223, 31-39. https://doi.org/10.1016/j.socscimed.2018.12.034

© 2019 Elsevier Ltd Though new or altered bodily sensations are a common occurrence they rarely transition to biomedically defined symptoms. When they do, sensations are subject to an appraisal process that can culminate in help-seeking. The transiti... Read More about Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal?.

Identifying potentially inappropriate prescribing in older people with dementia: a systematic review (2019)
Journal Article
Hukins, D., Macleod, U., & Boland, J. W. (2019). Identifying potentially inappropriate prescribing in older people with dementia: a systematic review. European Journal of Clinical Pharmacology, 75(4), 467-481. https://doi.org/10.1007/s00228-018-02612-x

Purpose: Older people with dementia are at risk of adverse events associated with potentially inappropriate prescribing. Aim: to describe (1) how international tools designed to identify potentially inappropriate prescribing have been used in studies... Read More about Identifying potentially inappropriate prescribing in older people with dementia: a systematic review.

Safety netting for primary care: Evidence from a literature review (2019)
Journal Article
Jones, D., Dunn, L., Watt, I., & Macleod, U. (2019). Safety netting for primary care: Evidence from a literature review. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(678), E70-E79. https://doi.org/10.3399/bjgp18X700193

© British Journal of General Practice.
Background: Ensuring patient safety is vital in primary care. One mechanism to increase patient safety is through a practice known as safety netting. Safety netting is widely recommended in national guidelines;... Read More about Safety netting for primary care: Evidence from a literature review.

Rapid review of factors associated with flexible sigmoidoscopy screening use (2018)
Journal Article
Kerrison, R. S., von Wagner, C., Green, T., Gibbins, M., Macleod, U., Hughes, M., Rees, C. J., Duffy, S., & McGregor, L. M. (2019). Rapid review of factors associated with flexible sigmoidoscopy screening use. Preventive Medicine, 120, 8-18. https://doi.org/10.1016/j.ypmed.2018.12.018

© 2019 The Authors Flexible sigmoidoscopy (FS) screening has been shown to reduce colorectal cancer (CRC) incidence and mortality among screened adults. The aim of this review was to identify patient-related factors associated with the screening test... Read More about Rapid review of factors associated with flexible sigmoidoscopy screening use.

Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: The MIR RCT (2018)
Journal Article
Kessler, D., Burns, A., Tallon, D., Lewis, G., Macneill, S., Round, J., Hollingworth, W., Chew-Graham, C., Anderson, I., Campbell, J., Dickens, C., Macleod, U., Gilbody, S., Davies, S., Peters, T. J., & Wiles, N. (2018). Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: The MIR RCT. Health Technology Assessment, 22(63), 1-136. https://doi.org/10.3310/hta22630

Background: Depression is usually managed in primary care and antidepressants are often the first-line treatment, but only half of those treated respond to a single antidepressant.
Objectives: To investigate whether or not combining mirtazapine wit... Read More about Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: The MIR RCT.

Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: Phase III randomised placebo controlled trial (MIR) (2018)
Journal Article
Kessler, D. S., MacNeill, S. J., Tallon, D., Lewis, G., Peters, T. J., Hollingworth, W., Round, J., Burns, A., Chew-Graham, C. A., Anderson, I. M., Shepherd, T., Campbell, J., Dickens, C. M., Carter, M., Jenkinson, C., Macleod, U., Gibson, H., Davies, S., & Wiles, N. J. (2018). Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: Phase III randomised placebo controlled trial (MIR). BMJ, 363, Article k4218. https://doi.org/10.1136/bmj.k4218

Objective: To investigate the effectiveness of combining mirtazapine with Serotonin-Noradrenaline Reuptake Inhibitor (SNRI) or Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants for patients in primary care who had not responded to an anti... Read More about Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: Phase III randomised placebo controlled trial (MIR).

Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer (2018)
Journal Article
Elliott, D., Hamdy, F. C., Leslie, T. A., Rosario, D., Dudderidge, T., Hindley, R., Emberton, M., Brewster, S., Sooriakumaran, P., Catto, J. W., Emara, A., Ahmed, H., Whybrow, P., le Conte, S., & Donovan, J. L. (2018). Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer. BJU international, 122(6), 970-977. https://doi.org/10.1111/bju.14432

Abstract
Objective
To describe how clinicians conceptualised equipoise in the PART (Partial prostate Ablation vs Radical prosTatectomy in intermediate‐risk unilateral clinically localised prostate cancer) feasibility study and how this affected rec... Read More about Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer.