All Outputs (81)

Patient-specific mental rehearsal with three-dimensional models before low anterior resection: randomized clinical trial (2020)
Journal Article
Yiasemidou, M., Mushtaq, F., Basheer, M., Galli, R., Panagiotou, D., Stock, S., Preston, N., Mon-Williams, M., Jayne, D. G., & Miskovic, D. (2021). Patient-specific mental rehearsal with three-dimensional models before low anterior resection: randomized clinical trial. BJS Open, 5(2), Article zraa004. https://doi.org/10.1093/bjsopen/zraa004

Background
It was hypothesized that preparing for a surgical procedure, taking into account individual patient characteristics, may facilitate the procedure and improve surgical quality. The aim of this study was to compare different case-specific,... Read More about Patient-specific mental rehearsal with three-dimensional models before low anterior resection: randomized clinical trial.

COVID-19 biomarkers for severity mapped to polycystic ovary syndrome (2020)
Journal Article
Moin, A. S. M., Sathyapalan, T., Atkin, S. L., & Butler, A. E. (2020). COVID-19 biomarkers for severity mapped to polycystic ovary syndrome. Journal of Translational Medicine, 18(1), Article 490. https://doi.org/10.1186/s12967-020-02669-2

Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis (2020)
Journal Article
Fraser, S. D., Crooks, M. G., Kaye, P. M., & Hart, S. P. (2021). Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis. ERJ Open Research, 7(1), https://doi.org/10.1183/23120541.00804-2020

Background: In sarcoidosis, blood monocytes, circulating precursors of granuloma macrophages, display enhanced inflammatory cytokine production, reduced expression of the regulatory (inhibitory) receptor CD200R, and altered subsets defined by CD14 an... Read More about Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis.

The impact of surgical site infection on hospitalisation, treatment costs, and health-related quality of life after vascular surgery (2020)
Journal Article
Totty, J., Moss, J. W. E., Barker, E., Mealing, S., Posnett, J., Chetter, I. C., & Smith, G. E. (in press). The impact of surgical site infection on hospitalisation, treatment costs, and health-related quality of life after vascular surgery. International wound journal, https://doi.org/10.1111/iwj.13526

Surgical site infections (SSI) substantially increase costs for healthcare providers because of additional treatments and extended patient recovery. The objective of this study was to assess the cost and health‐related quality of life impact of SSI,... Read More about The impact of surgical site infection on hospitalisation, treatment costs, and health-related quality of life after vascular surgery.

Patient, family and carer experiences of nutritional screening: a systematic review (2020)
Journal Article
Bullock, A., Greenley, S. L., Patterson, M. J., McKenzie, G. A. G., & Johnson, M. J. (2021). Patient, family and carer experiences of nutritional screening: a systematic review. Journal of Human Nutrition and Dietetics, 34(3), 595-603. https://doi.org/10.1111/jhn.12849

Background: Despite recommendations for nutritional risk screening of all inpatients, outpatients and care home residents, as well as work to assess clinician's experiences and the validity of tools, little attention has been paid to the experiences... Read More about Patient, family and carer experiences of nutritional screening: a systematic review.

Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease (2020)
Journal Article
Helo, Y., Searle, G. E., Borghese, F., Abraham, S., & Saleem, A. (2020). Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease. EJNMMI Research, 10(1), Article 147. https://doi.org/10.1186/s13550-020-00736-9

© 2020, The Author(s). Objective: Expression of the translocator protein (TSPO) on inflammatory cells has facilitated imaging of synovitis with TSPO-targeted positron emission tomography (PET). We aimed to quantitatively assess the specificity of the... Read More about Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease.

BTS Clinical Statement on pulmonary sarcoidosis (2020)
Journal Article
Thillai, M., Atkins, C. P., Crawshaw, A., Hart, S. P., Ho, L. P., Kouranos, V., Patterson, K., Screaton, N. J., Whight, J., & Wells, A. U. (in press). BTS Clinical Statement on pulmonary sarcoidosis. Thorax, https://doi.org/10.1136/thoraxjnl-2019-214348

A Patient's Guide to Pulmonary Fibrosis, First Edition (2020)
Other
Jagielka, K., Faulkner, E. C., Hart, S., & Nikitenko, L. L. (2020). A Patient's Guide to Pulmonary Fibrosis, First Edition

The surgical management of cutaneous abscesses: A UK cross-sectional survey (2020)
Journal Article
Thomas, O., Ramsay, A., Yiasemidou, M., Hardie, C., Ashmore, D., Macklin, C., Bandyopadhyay, D., Patel, B., Burke, J. R., & Jayne, D. (2020). The surgical management of cutaneous abscesses: A UK cross-sectional survey. Annals of Medicine and Surgery, 60, 654-659. https://doi.org/10.1016/j.amsu.2020.11.068

Aim
Cutaneous abscesses are one of the most common acute general surgery presentations. This study aimed to understand the current practice in the management of cutaneous abscesses in the United Kingdom (UK), once the decision has been made that acu... Read More about The surgical management of cutaneous abscesses: A UK cross-sectional survey.

Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren's syndrome (2020)
Journal Article
Jimenez-Royo, P., Bombardieri, M., Ciurtin, C., Kostapanos, M., Tappuni, A. R., Jordan, N., Saleem, A., Fuller, T., Port, K., Pontarini, E., Lucchesi, D., Janiczek, R., Galette, P., Searle, G., Patel, N., Kershaw, L., Gray, C., Ratia, N., van Maurik, A., de Groot, M., …Tarzi, R. (2021). Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren's syndrome. Rheumatology, 60(5), 2396-2408. https://doi.org/10.1093/rheumatology/keaa624

OBJECTIVES: To assess non-invasive imaging for detection and quantification of gland structure, inflammation and function in patients with primary Sjogren's syndrome (pSS) using PET-CT with 11C-Methionine (11C-MET; radiolabelled amino acid), and 18F-... Read More about Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren's syndrome.

Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication (2020)
Journal Article
Pymer, S., Ibeggazene, S., Palmer, J., Smith, G. E., Carroll, S., Ingle, L., Harwood, A., & Chetter, I. C. (2021). Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication. Journal of Cardiopulmonary Rehabilitation and Prevention, 41(3), 188-193. https://doi.org/10.1097/HCR.0000000000000551

Considering the Feasibility, Tolerability and Safety of High-Intensity Interval Training as a Novel Treatment for Patients with Intermittent Claudication.

Structured Abstract
Purpose: This study assessed the feasibility, tolerability, safety and... Read More about Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication.

The effect of variation of fatty substances found in the blood on patients with type 2 diabetes. ISRCTN27314990 (2020)
Other
Sathyapalan, T. (2020). The effect of variation of fatty substances found in the blood on patients with type 2 diabetes. ISRCTN27314990

Background and study aims
High blood sugar and fat content are well-recognised risk factors for causing the formation of obstructive plaques in arteries which lead to cardiovascular disease, for example heart attacks. From earlier studies, we know t... Read More about The effect of variation of fatty substances found in the blood on patients with type 2 diabetes. ISRCTN27314990.

Exercise training for intermittent claudication: A narrative review and summary of guidelines for practitioners (2020)
Journal Article
Harwood, A., Pymer, S., Ingle, L., Doherty, P., Chetter, I. C., Parmenter, B., Askew, C., & Tew, G. (2020). Exercise training for intermittent claudication: A narrative review and summary of guidelines for practitioners. BMJ Open Sport and Exercise Medicine, 6(1), Article e000897. https://doi.org/10.1136/bmjsem-2020-000897

Peripheral artery disease (PAD) is caused by atherosclerotic narrowing of the arteries supplying the lower limbs often resulting in intermittent claudication, evident as pain or cramping while walking. Supervised exercise training elicits clinically... Read More about Exercise training for intermittent claudication: A narrative review and summary of guidelines for practitioners.

Metabolic comparison of polycystic ovarian syndrome and control women in Middle Eastern and UK Caucasian populations (2020)
Journal Article
Butler, A. E., Abouseif, A., Dargham, S. R., Sathyapalan, T., & Atkin, S. L. (2020). Metabolic comparison of polycystic ovarian syndrome and control women in Middle Eastern and UK Caucasian populations. Scientific reports, 10(1), Article 18895. https://doi.org/10.1038/s41598-020-75109-2

© 2020, The Author(s). To determine if metabolic characteristics differed in women with and without polycystic ovary syndrome (PCOS) between a Caucasian and Middle East population. Comparative cross-sectional analysis. Demographic and metabolic data... Read More about Metabolic comparison of polycystic ovarian syndrome and control women in Middle Eastern and UK Caucasian populations.

Characterising non-melanoma skin cancer undergoing surgical management during the COVID-19 pandemic (2020)
Journal Article
Capitelli-McMahon, H., Hurley, A., Pinder, R., Matteucci, P., & Totty, J. (2021). Characterising non-melanoma skin cancer undergoing surgical management during the COVID-19 pandemic. Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 74(3), 644-710. https://doi.org/10.1016/j.bjps.2020.10.042

ERS guidelines on the diagnosis and treatment of chronic cough in adults and children [correction] (2020)
Journal Article
Morice, A. H., Millqvist, E., Bieksiene, K., Birring, S. S., Dicpinigaitis, P., Ribas, C. D., …Zacharasiewicz, A. (2020). ERS guidelines on the diagnosis and treatment of chronic cough in adults and children [correction]. European respiratory journal, 56(5), Article 51136-2019. https://doi.org/10.1183/13993003.51136-2019

Incomplete surgical excision of keratinocyte skin cancers: a systematic review and meta‐analysis (2020)
Journal Article
Nolan, G., Kiely, A., Totty, J., Wormald, J., Wade, R., Arbyn, M., & Jain, A. (2021). Incomplete surgical excision of keratinocyte skin cancers: a systematic review and meta‐analysis. British journal of dermatology, 184(6), 1033-1044. https://doi.org/10.1111/bjd.19660

Background
Keratinocyte or nonmelanoma skin cancer (NMSC) is the commonest malignancy worldwide. The usual treatment is surgical excision. Current guidelines underestimate incomplete excision rates.

Objectives
We aimed to determine the risk of i... Read More about Incomplete surgical excision of keratinocyte skin cancers: a systematic review and meta‐analysis.

Recent advances in drug discovery for diabetic kidney disease (2020)
Journal Article
Danta, C. C., Boa, A. N., Bhandari, S., Sathyapalan, T., & Xu, S. Z. (2021). Recent advances in drug discovery for diabetic kidney disease. Expert Opinion on Drug Discovery, 16(4), 447-461. https://doi.org/10.1080/17460441.2021.1832077

Introduction: Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease (ESRD), and 40% of patients with diabetes develop DKD. Although some pathophysiological mechanisms and drug targets of DKD have been described, the effectivenes... Read More about Recent advances in drug discovery for diabetic kidney disease.

Rhinovirus-16 increases ATP release in A549 cells without concomitant increase in production (2020)
Journal Article
Atkinson, S. K., Morice, A. H., & Sadofsky, L. R. (2020). Rhinovirus-16 increases ATP release in A549 cells without concomitant increase in production. ERJ Open Research, 6(4), Article 00159-2020. https://doi.org/10.1183/23120541.00159-2020

Human rhinovirus (RV) is the most common cause of upper respiratory tract infection (URTI) and chronic airway disease exacerbation. Cough is present in 50–80% of URTI cases, accompanied by heightened airway hypersensitivity, yet no effective treatmen... Read More about Rhinovirus-16 increases ATP release in A549 cells without concomitant increase in production.

Curcumin for the management of periodontal diseases: a review (2020)
Journal Article
Forouzanfar, F., Forouzanfar, A., Sathyapalan, T., Orafai, H. M., & Sahebkar, A. (2020). Curcumin for the management of periodontal diseases: a review. Current Pharmaceutical Design, 26(34), 4277-4284. https://doi.org/10.2174/1381612826666200513112607

Periodontal disease is one of the most common causes of tooth loss among adults. Research shows that inflammation is one of the crucial components in the initiation and progression of periodontitis. Various herbal medicines have recently been receivi... Read More about Curcumin for the management of periodontal diseases: a review.