All Outputs (209)

A sample-to-answer COVID-19 diagnostic device based on immiscible filtration and CRISPR-Cas12a-assisted detection (2022)
Journal Article
Ngamsom, B., Iles, A., Kamita, M., Kimani, R., Wakaba, P., Rodriguez-Mateos, P., Mungai, M., Dyer, C. E., Walter, C., Gitaka, J., & Pamme, N. (2022). A sample-to-answer COVID-19 diagnostic device based on immiscible filtration and CRISPR-Cas12a-assisted detection. Talanta Open, 6, Article 100166. https://doi.org/10.1016/j.talo.2022.100166

In response to the ongoing coronavirus disease 2019 (COVID-19) pandemic and disparities of vaccination coverage in low-and middle-income countries, it is vital to adopt a widespread testing and screening programme, combined with contact tracing, to m... Read More about A sample-to-answer COVID-19 diagnostic device based on immiscible filtration and CRISPR-Cas12a-assisted detection.

Two closely related ureotelic fish species of the genus Alcolapia express different levels of ammonium transporters in gills (2022)
Journal Article
White, L. J., Rose, M., Lawson, M., Joyce, D., Smith, A. M., Thomas, G. H., Dasmahapatra, K. K., & Pownall, M. E. (2022). Two closely related ureotelic fish species of the genus Alcolapia express different levels of ammonium transporters in gills. Biology Open, 11(11), Article bio059575. https://doi.org/10.1242/bio.059575

Most fish excrete their nitrogenous waste across the gills as ammonia through the activity of the Rhesus glycoprotein ammonium transporters. In contrast, fish of the subgenus Alcolapia (Oreochromis) are the only vertebrates that survive the extreme c... Read More about Two closely related ureotelic fish species of the genus Alcolapia express different levels of ammonium transporters in gills.

Sex and gametogenesis stage are strong drivers of gene expression in Mytilus edulis exposed to environmentally relevant plasticiser levels and pH 7.7 (2022)
Journal Article
Mincarelli, L., Chapman, E. C., Rotchell, J. M., Turner, A., & Wollenberg Valero, K. C. (in press). Sex and gametogenesis stage are strong drivers of gene expression in Mytilus edulis exposed to environmentally relevant plasticiser levels and pH 7.7. Environmental science and pollution research, https://doi.org/10.1007/s11356-022-23801-3

Plastic pollution and changes in oceanic pH are both pressing environmental issues. Little emphasis, however, has been placed on the influence of sex and gametogenesis stage when investigating the effects of such stressors. Here, we examined histolog... Read More about Sex and gametogenesis stage are strong drivers of gene expression in Mytilus edulis exposed to environmentally relevant plasticiser levels and pH 7.7.

Development of a skin-on-a-chip platform for the study of wound healing (2022)
Thesis
Talar, K. Development of a skin-on-a-chip platform for the study of wound healing. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4508234

Wound healing abnormalities and non-healing chronic wounds are a major clinical problem, primarily affecting diabetic and elderly patients. Wound management associated costs resulted in a £5.3 billion financial burden to the NHS between 2012 and 2013... Read More about Development of a skin-on-a-chip platform for the study of wound healing.

Oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera (2022)
Journal Article
Clark, B., Elkin, J., Marconi, A., Turner, G. F., Smith, A. M., Joyce, D., Miska, E. A., Juntti, S. A., & Santos, M. E. (2022). Oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera. Royal Society Open Science, 9(4), Article 220077. https://doi.org/10.1098/rsos.220077

Identifying genetic loci underlying trait variation provides insights into the mechanisms of diversification, but demonstrating causality and characterizing the role of genetic loci requires testing candidate gene function, often in non-model species... Read More about Oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera.

Study of the composition, processing and microstructure relationship of light alloys (2022)
Thesis
Sumayli, A. I. Study of the composition, processing and microstructure relationship of light alloys. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4508161

This research consists of two main parts. The first part concerns the study of the effect of pulse electromagnetic fields on the microstructural evolution and the hardness of an Al-20%Si alloy. A pulse magnetic field apparatus is used to produce diff... Read More about Study of the composition, processing and microstructure relationship of light alloys.

Outdoor atmospheric microplastics within the Humber region (United Kingdom): Quantification and chemical characterisation of deposited particles present (2022)
Journal Article
Jenner, L., Sadofsky, L., Danopoulos, E., Chapman, E., White, D., Jenkins, R., & Rotchell, J. M. (2022). Outdoor atmospheric microplastics within the Humber region (United Kingdom): Quantification and chemical characterisation of deposited particles present. Atmosphere, 13(2), Article 265. https://doi.org/10.3390/atmos13020265

Atmospheric microplastics (MPs) have been consistently captured within air samples on a global scale. Locations with high human activity are reported to have high MP levels. An urban sampling site in the Humber region (U.K.) has been sampled over a 1... Read More about Outdoor atmospheric microplastics within the Humber region (United Kingdom): Quantification and chemical characterisation of deposited particles present.

Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study (2022)
Journal Article
Zhu, J., Li, J., Chapman, E. C., Shi, H., Ciocan, C. M., Chen, K., Shi, X., Zhou, J. L., Sun, P., Zheng, Y., & Rotchell, J. M. (in press). Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study. Bulletin of Environmental Contamination and Toxicology, https://doi.org/10.1007/s00128-022-03461-2

This preliminary survey analysed mussel atresia incidences, estrogen-responsive and apoptotic-specific molecular end points, and aqueous and gonadal levels of selected estrogens from the East China coast. Estrogen levels were low (e.g. < LOD-28.36ng/... Read More about Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study.

A Review of Distributed Ledger Technologies in the Machine Economy: Challenges and Opportunities in Industry and Research (2022)
Presentation / Conference Contribution
Khan, M. D., Schaefer, D., & Milisavljevic-Syed, J. A Review of Distributed Ledger Technologies in the Machine Economy: Challenges and Opportunities in Industry and Research. Presented at 55th CIRP Conference on Manufacturing Systems 2022, Lugano, Switzerland

Blockchain Technology has gained prominence since 2008 with trust, reliability, speed, and transparency becoming major advantages. It has also been applied and researched within a multitude of industry applications ranging from manufacturing to finan... Read More about A Review of Distributed Ledger Technologies in the Machine Economy: Challenges and Opportunities in Industry and Research.

A Decision-Based Framework for Predictive Maintenance Technique Selection in Industry 4.0 (2022)
Presentation / Conference Contribution
Li, J., Schaefer, D., & Milisavljevic-Syed, J. A Decision-Based Framework for Predictive Maintenance Technique Selection in Industry 4.0. Presented at 55th CIRP Conference on Manufacturing Systems 2022, Lugano, Switzerland

Maintenance is defined as the actions that allow machines and equipment to work for an extended period of time by retaining and restoring equipment to its original state. In Industry 4.0 context, Predictive Maintenance (PdM) is a strategy that utiliz... Read More about A Decision-Based Framework for Predictive Maintenance Technique Selection in Industry 4.0.

Supply Chain Management 4.0: Looking Backward, Looking Forward (2022)
Presentation / Conference Contribution
Khan, M. D., Schaefer, D., & Milisavljevic-Syed, J. Supply Chain Management 4.0: Looking Backward, Looking Forward. Presented at 55th CIRP Conference on Manufacturing Systems, Lugano, Switzerland

About ten years ago, a bold vision with a prospect of largely autonomous factories of the future with digitized processes, data-driven smart applications, and seamlessly integrated supply chains was born and quickly became known as Industry 4.0 or ak... Read More about Supply Chain Management 4.0: Looking Backward, Looking Forward.

Strategies for Achieving Pre-emptive Resilience in Military Supply Chains (2022)
Presentation / Conference Contribution
Sani, S., Schaefer, D., & Milisavljevic-Syed, J. Strategies for Achieving Pre-emptive Resilience in Military Supply Chains. Presented at 55th CIRP Conference on Manufacturing Systems 2022, Lugano, Switzerland

As technological advancement is rapidly evolving modern warfare, military supply chains are becoming more dynamic and complex with high vulnerability to unexpected disruptions. To increase their overall resilience against such unexpected disruptions,... Read More about Strategies for Achieving Pre-emptive Resilience in Military Supply Chains.

Citizen-led sampling to monitor phosphate levels in freshwater environments using a simple paper microfluidic device (2021)
Journal Article
Richardson, S., Iles, A., Rotchell, J. M., Charlson, T., Hanson, A., Lorch, M., & Pamme, N. (2021). Citizen-led sampling to monitor phosphate levels in freshwater environments using a simple paper microfluidic device. PLoS ONE, 16(12), Article e0260102. https://doi.org/10.1371/journal.pone.0260102

Contamination of waterways is of increasing concern, with recent studies demonstrating elevated levels of antibiotics, antidepressants, household, agricultural and industrial chemicals in freshwater systems. Thus, there is a growing demand for method... Read More about Citizen-led sampling to monitor phosphate levels in freshwater environments using a simple paper microfluidic device.

The Uptake of Sporopollenin Exine Capsules and Associated Bioavailability of Adsorbed Oestradiol in Selected Aquatic Invertebrates (2021)
Journal Article
Chapman, E., Meichanetzoglou, A., Boa, A. N., Hetjens, H., Faetsch, S., Teuchies, J., Höss, S., Moore, D., Bervoets, L., Kay, P., Heise, S., Walker, P., & Rotchell, J. M. (2021). The Uptake of Sporopollenin Exine Capsules and Associated Bioavailability of Adsorbed Oestradiol in Selected Aquatic Invertebrates. Bulletin of Environmental Contamination and Toxicology, 107, 876–882. https://doi.org/10.1007/s00128-021-03364-8

Lycopodium clavatum sporopollenin exine capsules (SpECs) are known to both adsorb and absorb chemicals. The aim of the present work was to determine whether oestradiol (E2) is ‘bioavailable’ to bioindicator species, either pre-adsorbed to, or in the... Read More about The Uptake of Sporopollenin Exine Capsules and Associated Bioavailability of Adsorbed Oestradiol in Selected Aquatic Invertebrates.

Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro (2021)
Journal Article
Collins, T., Pyne, E., Christensen, M., Iles, A., Pamme, N., & Pires, I. M. (2021). Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro. Biomicrofluidics, 15(4), Article 044103. https://doi.org/10.1063/5.0061373

The majority of cancer deaths are linked to tumor spread, or metastasis, but 3D in vitro metastasis models relevant to the tumor microenvironment (including interstitial fluid flow) remain an area of unmet need. Microfluidics allows us to introduce c... Read More about Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro.

Polymer/TiO2Nanorod Nanocomposite Optical Memristor Device (2021)
Journal Article
Jaafar, A. H., Al Chawa, M. M., Cheng, F., Kelly, S. M., Picos, R., Tetzlaff, R., & Kemp, N. T. (2021). Polymer/TiO2Nanorod Nanocomposite Optical Memristor Device. Journal of physical chemistry. C, 125(27), 14965–14973. https://doi.org/10.1021/acs.jpcc.1c02799

Modulation of resistive switching memory by light opens the route to new optoelectronic devices that can be controlled both optically and electronically. Applications include integrated circuits with memory elements switchable by light and neuromorph... Read More about Polymer/TiO2Nanorod Nanocomposite Optical Memristor Device.

Consequences of combined exposure to thermal stress and the plasticiser DEHP in Mytilus spp. differ by sex (2021)
Journal Article
Mincarelli, L. F., Rotchell, J. M., Chapman, E. C., Turner, A. P., & Wollenberg Valero, K. C. (2021). Consequences of combined exposure to thermal stress and the plasticiser DEHP in Mytilus spp. differ by sex. Marine pollution bulletin, 170, Article 112624. https://doi.org/10.1016/j.marpolbul.2021.112624

Little is known about the combined effect of environmental factors and contaminants on commercially important marine species, and whether this effect differs by sex. In this study, blue mussels were exposed for seven days to both single and combined... Read More about Consequences of combined exposure to thermal stress and the plasticiser DEHP in Mytilus spp. differ by sex.

A lab-on-a-chip platform for integrated extraction and detection of SARS-CoV-2 RNA in resource-limited settings (2021)
Journal Article
Rodriguez-Mateos, P., Ngamsom, B., Walter, C., Dyer, C. E., Gitaka, J., Iles, A., & Pamme, N. (2021). A lab-on-a-chip platform for integrated extraction and detection of SARS-CoV-2 RNA in resource-limited settings. Analytica Chimica Acta, 1177, Article 338758. https://doi.org/10.1016/j.aca.2021.338758

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the unprecedented global pandemic of coronavirus disease-2019 (COVID-19). Efforts are needed to develop rapid and accurate diagnostic tools for extensive testing, allowing for ef... Read More about A lab-on-a-chip platform for integrated extraction and detection of SARS-CoV-2 RNA in resource-limited settings.

Design Engineering in the Age of Industry 4.0 (2021)
Journal Article
Jiao, R., Commuri, S., Panchal, J., Milisavljevic-Syed, J., Allen, J. K., Mistree, F., & Schaefer, D. (2021). Design Engineering in the Age of Industry 4.0. Journal of Mechanical Design, 143(7), Article 070801. https://doi.org/10.1115/1.4051041

Industry 4.0 is based on the digitization of manufacturing industries and has raised the prospect for substantial improvements in productivity, quality, and customer satisfaction. This digital transformation not only affects the way products are manu... Read More about Design Engineering in the Age of Industry 4.0.

Edible surfactants at fluid-fluid interfaces (2021)
Thesis
Liu, Y. Edible surfactants at fluid-fluid interfaces. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4223435

This thesis probes into the adsorption properties of several edible surfactants/fats at a range of fluid-fluid interfaces, e.g. air-oil, air-water and water-oil. Based on this, various colloidal materials are fabricated including aqueous and oil foam... Read More about Edible surfactants at fluid-fluid interfaces.