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“So, when a woman becomes ill, the total structure of the family is affected, they can’t do anything…” Voices from the community on women with breast cancer in India: a qualitative focus group study (2021)
Journal Article
Daniel, S., Venkateswaran, C., Singh, C., Hutchinson, A., & Johnson, M. J. (in press). “So, when a woman becomes ill, the total structure of the family is affected, they can’t do anything…” Voices from the community on women with breast cancer in India: a qualitative focus group study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, https://doi.org/10.1007/s00520-021-06475-4

Background: Psychological symptoms are common in women with breast cancer and profoundly affect their role in the family and wider community, varying across cultural backgrounds. Breast cancer is becoming the most common cancer among women in India.... Read More about “So, when a woman becomes ill, the total structure of the family is affected, they can’t do anything…” Voices from the community on women with breast cancer in India: a qualitative focus group study.

Inhibition of arginine methylation impairs platelet function (2021)
Journal Article
Marsden, A. J., Riley, D. R. J., Barry, A., Khalil, J. S., Guinn, B. A., Kemp, N. T., …Beltran-Alvarez, P. (in press). Inhibition of arginine methylation impairs platelet function. ACS Pharmacology & Translational Science, https://doi.org/10.1021/acsptsci.1c00135

Protein arginine methyltransferases (PRMTs) catalyze the transfer of methyl groups to arginine residues in proteins. PRMT inhibitors are novel, promising drugs against cancer that are currently in clinical trials, which include oral administration of... Read More about Inhibition of arginine methylation impairs platelet function.

A comparative experimental study of visual brain event-related potentials to a working memory task: virtual reality head-mounted display versus a desktop computer screen (2021)
Journal Article
Aksoy, M., Ufodiama, C. E., Bateson, A. D., Martin, S., & Asghar, A. U. (2021). A comparative experimental study of visual brain event-related potentials to a working memory task: virtual reality head-mounted display versus a desktop computer screen. Experimental Brain Research, 239(10), 3007–3022. https://doi.org/10.1007/s00221-021-06158-w

Virtual reality head mounted display (VR HMD) systems are increasingly utilised in combination with electroencephalography (EEG) in the experimental study of cognitive tasks. The aim of our investigation was to determine the similarities/differences... Read More about A comparative experimental study of visual brain event-related potentials to a working memory task: virtual reality head-mounted display versus a desktop computer screen.

Professionals’, patients’ and families’ views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process (2021)
Journal Article
Reedy, F., Pearson, M., Greenley, S., Clark, J., Currow, D. C., Bajwah, S., …Johnson, M. J. (in press). Professionals’, patients’ and families’ views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process. Palliative medicine, https://doi.org/10.1177/02692163211032114

Background: In combination with non-pharmacological interventions, opioids may safely reduce chronic breathlessness in patients with severe illness. However, implementation in clinical practice varies. Aim: To synthesise the published literature rega... Read More about Professionals’, patients’ and families’ views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process.

Outcomes and characteristics of COVID-19 patients treated with continuous positive airway pressure/high-flow nasal oxygen outside the intensive care setting (2021)
Journal Article
Sykes, D. L., Crooks, M. G., Thu, K. T., Brown, O. I., Tyrer, T. J., Rennardson, J., Littlefield, C., & Faruqi, S. (2021). Outcomes and characteristics of COVID-19 patients treated with continuous positive airway pressure/high-flow nasal oxygen outside the intensive care setting. ERJ Open Research, 7(4), Article 00318-2021. https://doi.org/10.1183/23120541.00318-2021

Background Continuous positive airway pressure (CPAP) and high-flow nasal oxygen (HFNO) have been used to manage hypoxaemic respiratory failure secondary to coronavirus disease 2019 (COVID-19) pneumonia. Limited data are available for patients treate... Read More about Outcomes and characteristics of COVID-19 patients treated with continuous positive airway pressure/high-flow nasal oxygen outside the intensive care setting.

The vertebral artery blood supply to the brain and its relationship with cognition across the taxonomic classes: Mammalia and Aves (2021)
Presentation / Conference Contribution
Lunn, A., Winder, I. C., & Shaw, V. (2021, July). The vertebral artery blood supply to the brain and its relationship with cognition across the taxonomic classes: Mammalia and Aves. Poster presented at Anatomical Society Summer Meeting 2021: Cutting Edge Anatomy, Glasgow

Human brains require the most energy per unit of mass of any animal and also have the largest cortical neuron count, which is afforded by having the largest primate brain and abiding by economic scaling rules. Cortical neuron count is one of the most... Read More about The vertebral artery blood supply to the brain and its relationship with cognition across the taxonomic classes: Mammalia and Aves.

Improving caring quality for people with dementia in nursing homes using IPOS-Dem: A stepped-wedge cluster randomized controlled trial protocol (2021)
Journal Article
Spichiger, F., Koppitz, A. L., De Wolf-Linder, S., Murtagh, F. E., Volken, T., & Larkin, P. (in press). Improving caring quality for people with dementia in nursing homes using IPOS-Dem: A stepped-wedge cluster randomized controlled trial protocol. Journal of advanced nursing, https://doi.org/10.1111/jan.14953

Aims: We aim to evaluate the effectiveness of the Integrated Palliative Care Outcome Scale for people with dementia-based case studies to improve the caring quality for people with dementia in nursing homes by frontline staff and family members. Back... Read More about Improving caring quality for people with dementia in nursing homes using IPOS-Dem: A stepped-wedge cluster randomized controlled trial protocol.

The association between mental health and shift work: Findings from the Atlantic PATH study (2021)
Journal Article
Sweeney, E., Cui, Y., Yu, Z. M., Dummer, T. J., DeClercq, V., Forbes, C., Grandy, S. A., Keats, M. R., & Adisesh, A. (2021). The association between mental health and shift work: Findings from the Atlantic PATH study. Preventive Medicine, 150, Article 106697. https://doi.org/10.1016/j.ypmed.2021.106697

We evaluated the relationship between mental health and shift work in the Atlantic Partnership for Tomorrow's Health (PATH) cohort study. In a matched study with 12,413 participants, including 4155 shift workers and 8258 non-shift workers, we utilize... Read More about The association between mental health and shift work: Findings from the Atlantic PATH study.

Predictors of diabetes-related distress before and after FreeStyle Libre-1 use: Lessons from the Association of British Clinical Diabetologists nationwide study (2021)
Journal Article
Deshmukh, H., Wilmot, E. G., Gregory, R., Barnes, D., Narendran, P., Saunders, S., …Sathyapalan, T. (2021). Predictors of diabetes-related distress before and after FreeStyle Libre-1 use: Lessons from the Association of British Clinical Diabetologists nationwide study. Diabetes, Obesity and Metabolism, 23(10), 2261-2268. https://doi.org/10.1111/dom.14467

Aim: To identify the baseline demographic and clinical characteristics associated with diabetes-related distress (DRD) and factors associated with improvement in DRD after initiating use of the FreeStyle Libre (FSL) in people living with type 1 diabe... Read More about Predictors of diabetes-related distress before and after FreeStyle Libre-1 use: Lessons from the Association of British Clinical Diabetologists nationwide study.

High-fidelity simulation and virtual reality: An evaluation of medical students' experiences (2021)
Journal Article
Macnamara, A. F., Bird, K., Rigby, A., Sathyapalan, T., & Hepburn, D. (2021). High-fidelity simulation and virtual reality: An evaluation of medical students' experiences. BMJ Simulation & Technology Enhanced Learning, 7(6), 528-535. https://doi.org/10.1136/bmjstel-2020-000625

Background: Simulation technology is widely used in medical education, providing an environment in which students can develop and practise a multitude of skills that are relevant to clinical practice, without the risk of harm to patients. Methods: We... Read More about High-fidelity simulation and virtual reality: An evaluation of medical students' experiences.

Current understanding of nonsurgical interventions for refractory differentiated thyroid cancer: a systematic review (2021)
Journal Article
Jones, H., Green, V., England, J., & Greenman, J. (2021). Current understanding of nonsurgical interventions for refractory differentiated thyroid cancer: a systematic review. Future Science OA, 7(7), https://doi.org/10.2144/fsoa-2021-0041

Thyroid cancer incidence and related mortality is increasing year-on-year, and although treatment for early disease with surgery and radioiodine results in a 98% 5-year survival rate, recurrence and treatment refractory disease is evident in an unacc... Read More about Current understanding of nonsurgical interventions for refractory differentiated thyroid cancer: a systematic review.

A mixed-method feasibility study of a novel transitional regime of incremental haemodialysis: study design and protocol (2021)
Journal Article
Twiddy, M., Hazara, A., Bhandari, S., & Allgar, V. (in press). A mixed-method feasibility study of a novel transitional regime of incremental haemodialysis: study design and protocol. Clinical and Experimental Nephrology, https://doi.org/10.1007/s10157-021-02072-1

Background: Incremental haemodialysis/haemodiafiltration (HD) may help reduce early mortality rates in patients starting HD. This mixed-method feasibility study aims to test the acceptability, tolerance and safety of a novel incremental HD regime, an... Read More about A mixed-method feasibility study of a novel transitional regime of incremental haemodialysis: study design and protocol.

An Updated Systematic Review and Meta-Analysis of Home-based Exercise Programmes for Individuals with Intermittent Claudication. (2021)
Journal Article
Pymer, S., Ibeggazene, S., Palmer, J., Tew, G., Ingle, L., Smith, G., …Harwood, A. (2021). An Updated Systematic Review and Meta-Analysis of Home-based Exercise Programmes for Individuals with Intermittent Claudication. Journal of vascular surgery, 74(6), 2076-2085.e20

Objectives: Supervised exercise programmes (SEP) are effective for improving walking distance in patients with intermittent claudication (IC) but provision and uptake rates are sub-optimal. Access to such programmes has also been halted by the Corona... Read More about An Updated Systematic Review and Meta-Analysis of Home-based Exercise Programmes for Individuals with Intermittent Claudication..

Household indoor microplastics within the Humber region (United Kingdom): quantification and chemical characterisation of particles present (2021)
Journal Article
Jenner, L., Sadofsky, L., Danopoulos, E., & Rotchell, J. M. (2021). Household indoor microplastics within the Humber region (United Kingdom): quantification and chemical characterisation of particles present. Atmospheric Environment, 259, Article 118512. https://doi.org/10.1016/j.atmosenv.2021.118512

Knowledge regarding the presence of suspended microplastics (MPs) within the air is lacking, especially indoors, yet the importance of indoor air quality and human health is rising. This study is the first to report MPs within multiple homes over a 6... Read More about Household indoor microplastics within the Humber region (United Kingdom): quantification and chemical characterisation of particles present.

The Effect of Free Androgen Index on the Quality of Life of Women With Polycystic Ovary Syndrome: A Cross-Sectional Study (2021)
Journal Article
Abdalla, M. A., Deshmukh, H., Mohammed, I., Atkin, S., Reid, M., & Sathyapalan, T. (2021). The Effect of Free Androgen Index on the Quality of Life of Women With Polycystic Ovary Syndrome: A Cross-Sectional Study. Frontiers in Physiology, 12, Article 652559. https://doi.org/10.3389/fphys.2021.652559

Purpose: Free androgen index (FAI) and anti-Mullerian hormone (AMH) are independently associated with polycystic ovary syndrome (PCOS). This study aimed to describe the relationship between these two markers and health-related quality of life (HR-QoL... Read More about The Effect of Free Androgen Index on the Quality of Life of Women With Polycystic Ovary Syndrome: A Cross-Sectional Study.

Feasibility, acceptability, and efficacy of online supportive care for individuals living with and beyond lung cancer: a systematic review (2021)
Journal Article
Curry, J., Patterson, M., Greenley, S., Pearson, M., & Forbes, C. (in press). Feasibility, acceptability, and efficacy of online supportive care for individuals living with and beyond lung cancer: a systematic review. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, https://doi.org/10.1007/s00520-021-06274-x

Purpose: To examine the evidence of the feasibility, acceptability, and potential efficacy of online supportive care interventions for people living with and beyond lung cancer (LWBLC). Methods: Studies were identified through searches of Medline, EM... Read More about Feasibility, acceptability, and efficacy of online supportive care for individuals living with and beyond lung cancer: a systematic review.

‘It’s almost superstition: If I don’t think about it, it won’t happen’. Public knowledge and attitudes towards advance care planning: A sequential mixed methods study (2021)
Journal Article
McIlfatrick, S., Slater, P., Bamidele, O., Muldrew, D., Beck, E., & Hasson, F. (2021). ‘It’s almost superstition: If I don’t think about it, it won’t happen’. Public knowledge and attitudes towards advance care planning: A sequential mixed methods study. Palliative medicine, 35(7), 1356-1365. https://doi.org/10.1177/02692163211015838

Background: Internationally, participation in advance care planning is low. Whilst a community action approach is advocated, what the public know and understand about advance care planning is unknown. Aim: To assess public awareness, knowledge and at... Read More about ‘It’s almost superstition: If I don’t think about it, it won’t happen’. Public knowledge and attitudes towards advance care planning: A sequential mixed methods study.

Development and evaluation of a smartphone-based electroencephalography (EEG) system (2021)
Journal Article
Bateson, A. D., & Asghar, A. U. (2021). Development and evaluation of a smartphone-based electroencephalography (EEG) system. IEEE Access, 9, 75650-75667. https://doi.org/10.1109/ACCESS.2021.3079992

The aim of the study was to design, develop and evaluate a general-purpose EEG platform which integrates with a smartphone. The target specification was a system with 19 EEG channels and data stored onto the smartphone via a Wi-Fi connection. The har... Read More about Development and evaluation of a smartphone-based electroencephalography (EEG) system.

Amyloid-related protein changes associated with dementia differ according to severity of hypoglycemia (2021)
Journal Article
Moin, A. S. M., Kahal, H., Al-Qaissi, A., Kumar, N., Sathyapalan, T., Atkin, S. L., & Butler, A. E. (2021). Amyloid-related protein changes associated with dementia differ according to severity of hypoglycemia. BMJ Open Diabetes Research and Care, 9(1), Article e002211. https://doi.org/10.1136/bmjdrc-2021-002211

Introduction Hypoglycemia in type 2 diabetes (T2D) may increase risk for Alzheimer’s disease (AD), but no data on changes in AD-related proteins with differing degrees of hypoglycemia exist. We hypothesized that milder prolonged hypoglycemia would ca... Read More about Amyloid-related protein changes associated with dementia differ according to severity of hypoglycemia.