All Outputs (461)

Face and content validity, acceptability, feasibility, and implementability of a novel outcome measure for children with life-limiting or life-threatening illness in three sub-Saharan African countries (2022)
Journal Article
Namisango, E., Bristowe, K., Murtagh, F. E., Downing, J., Powell, R. A., Atieno, M., …Harding, R. (2022). Face and content validity, acceptability, feasibility, and implementability of a novel outcome measure for children with life-limiting or life-threatening illness in three sub-Saharan African countries. Palliative medicine, 36(7), 1140-1153. https://doi.org/10.1177/02692163221099583

Background: The Children’s Palliative Care Outcome Scale (C-POS) is the first measure developed for children with life-limiting and -threatening illness. It is essential to determine whether the measure addresses what matters to children, and if they... Read More about Face and content validity, acceptability, feasibility, and implementability of a novel outcome measure for children with life-limiting or life-threatening illness in three sub-Saharan African countries.

What do we do with all the evidence for symptoms in palliative care? (2022)
Journal Article
Boland, J. W., Koffman, J., & Boland, E. G. (2022). What do we do with all the evidence for symptoms in palliative care?. Palliative medicine, 36(6), 892-894. https://doi.org/10.1177/02692163221098005

Thinking About the Future, Symptom Control and Other Aspects of Palliative Care in Advanced CKD (2022)
Book Chapter
Murtagh, F. E., Wilson, J., & Davison, S. N. (2022). Thinking About the Future, Symptom Control and Other Aspects of Palliative Care in Advanced CKD. In M. Harber (Ed.), Primer on Nephrology (1163-1174). Cham: Springer. https://doi.org/10.1007/978-3-030-76419-7_68

Palliative and supportive care have always been important for those with advanced CKD, but – until recently – there has been little research or evidence to inform best care. This is changing rapidly. This chapter draws on recent evidence to provide a... Read More about Thinking About the Future, Symptom Control and Other Aspects of Palliative Care in Advanced CKD.

Tumour-Associated Tissue Factor (TF)-mRNA Is A Precursor for Rapid TF-Microvesicle Release and A Potential Predictive Marker for the Risk of Pulmonary Embolism (PE) in Gastrointestinal Cancer Patients (2022)
Journal Article
Ettelaie, C., Benelhaj, N., Featherby, S., Haque, F., Johnson, M., Cooke, J., & Maraveyas, A. (2022). Tumour-Associated Tissue Factor (TF)-mRNA Is A Precursor for Rapid TF-Microvesicle Release and A Potential Predictive Marker for the Risk of Pulmonary Embolism (PE) in Gastrointestinal Cancer Patients. Journal of Biotechnology and Biomedicine, 5(2), 78-93. https://doi.org/10.26502/jbb.2642-280050

Predicting which cancer patients are at risk of thrombosis remains a key challenge to effective thromboprophylaxis. This study was based on the hypothesis that the rapid release of TF-containing MV occurs in cancer cells that possess high levels of T... Read More about Tumour-Associated Tissue Factor (TF)-mRNA Is A Precursor for Rapid TF-Microvesicle Release and A Potential Predictive Marker for the Risk of Pulmonary Embolism (PE) in Gastrointestinal Cancer Patients.

Making Sense of Evidence: Using Research Training to Promote Organisational Change (2022)
Book Chapter
Wilkinson, K., Boyd, K., Pearson, M., Farrimond, H., Lang, I. A., Fleischer, D., Poole, A., Ralph, N., & Rappert, B. (2022). Making Sense of Evidence: Using Research Training to Promote Organisational Change. In George Mason Police Research Group, & D. Weisburd (Eds.), Translational Criminology in Policing (64-85). Routledge. https://doi.org/10.4324/9781003153009-7

The International Association of Chiefs of Police (IACP) is perhaps the most prominent advocate for such partnerships. Problems confronting public institutions have become more complex in recent years. A number of fields and disciplines have recogniz... Read More about Making Sense of Evidence: Using Research Training to Promote Organisational Change.

Translating qualitative data into intervention content using the Theoretical Domains Framework and stakeholder co-design: a worked example from a study of cervical screening attendance in older women (2022)
Journal Article
Bravington, A., Chen, H., Dyson, J., Jones, L., Dalgliesh, C., Bryan, A., Patnick, J., & Macleod, U. (2022). Translating qualitative data into intervention content using the Theoretical Domains Framework and stakeholder co-design: a worked example from a study of cervical screening attendance in older women. BMC health services research, 22(1), Article 610. https://doi.org/10.1186/s12913-022-07926-2

Background: Previous screening interventions have demonstrated a series of features related to social determinants which have increased uptake in targeted populations, including the assessment of health beliefs and barriers to screening attendance as... Read More about Translating qualitative data into intervention content using the Theoretical Domains Framework and stakeholder co-design: a worked example from a study of cervical screening attendance in older women.

Persisting breathlessness and activities reduced or ceased: a population study in older men (2022)
Journal Article
Kochovska, S., Currow, D., Chang, S., Johnson, M., Ferreira, D., Morgan, D., …Ekström, M. (2022). Persisting breathlessness and activities reduced or ceased: a population study in older men. BMJ Open Respiratory Research, 9(1), Article e001168. https://doi.org/10.1136/bmjresp-2021-001168

INTRODUCTION: Breathlessness is debilitating and increases in prevalence with age, with people progressively reducing their everyday activities to 'self-manage' it. This study aimed to evaluate the impact of breathlessness on function in terms of act... Read More about Persisting breathlessness and activities reduced or ceased: a population study in older men.

Implementing the battery-operated hand-held fan as an evidence-based, non-pharmacological intervention for chronic breathlessness in patients with chronic obstructive pulmonary disease (COPD): a qualitative study of the views of specialist respiratory clinicians (2022)
Journal Article
Luckett, T., Roberts, M., Smith, T., Garcia, M., Dunn, S., Swan, F., …Johnson, M. J. (2022). Implementing the battery-operated hand-held fan as an evidence-based, non-pharmacological intervention for chronic breathlessness in patients with chronic obstructive pulmonary disease (COPD): a qualitative study of the views of specialist respiratory clinicians. BMC Pulmonary Medicine, 22(1), Article 129. https://doi.org/10.1186/s12890-022-01925-z

INTRODUCTION: The battery-operated hand-held fan ('fan') is an inexpensive and portable non-pharmacological intervention for chronic breathlessness. Evidence from randomised controlled trials suggests the fan reduces breathlessness intensity and impr... Read More about Implementing the battery-operated hand-held fan as an evidence-based, non-pharmacological intervention for chronic breathlessness in patients with chronic obstructive pulmonary disease (COPD): a qualitative study of the views of specialist respiratory clinicians.

Lower workforce participation is associated with more severe persisting breathlessness (2022)
Journal Article
Clark, J., Chang, S., Kinchin, I., Ferreira, D., Kochovska, S., Morgan, D., …Currow, D. C. (2022). Lower workforce participation is associated with more severe persisting breathlessness. BMC Pulmonary Medicine, 22(1), Article 93. https://doi.org/10.1186/s12890-022-01861-y

Background: Not being able to work has negative health, social and financial consequences. Persisting breathlessness is prevalent in working-aged people. Is it associated with lower workforce participation? This study, using the South Australian Heal... Read More about Lower workforce participation is associated with more severe persisting breathlessness.

Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review (2022)
Journal Article
Baddeley, E., Mann, M., Bravington, A., Johnson, M. J., Currow, D., Murtagh, F. E., …Noble, S. (in press). Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review. Palliative medicine, https://doi.org/10.1177/02692163221081331

Background: Malignant bowel obstruction occurs in up to 50% of people with advanced ovarian and 15% of people with gastrointestinal cancers. Evaluation and comparison of interventions to manage symptoms are hampered by inconsistent evaluations of eff... Read More about Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review.

COVID-19: Impact on Pediatric Palliative Care (2022)
Journal Article
Scott, H. M., Coombes, L., Braybrook, D., Roach, A., Harðardóttir, D., Bristowe, K., …Harding, R. (in press). COVID-19: Impact on Pediatric Palliative Care. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2022.02.330

Context: Children and young people with life-limiting or life-threatening conditions and their families are potentially vulnerable during COVID-19 lockdowns due to pre-existing high clinical support needs and social participation limitations. Objecti... Read More about COVID-19: Impact on Pediatric Palliative Care.

Towards codesign in respiratory care: development of an implementation-ready intervention to improve guideline-adherent adult asthma care across primary and secondary care settings (The SENTINEL Project) (2022)
Journal Article
Crowther, L., Pearson, M., Cummings, H., & Crooks, M. G. (2022). Towards codesign in respiratory care: development of an implementation-ready intervention to improve guideline-adherent adult asthma care across primary and secondary care settings (The SENTINEL Project). BMJ Open Respiratory Research, 9(1), Article e001155. https://doi.org/10.1136/bmjresp-2021-001155

Short-acting beta agonist (SABA) overuse (≥3 canisters annually) is associated with worse asthma outcomes and accounts for the majority of greenhouse gas emissions from asthma inhalers in England. Reducing SABA overuse aligns with the National Health... Read More about Towards codesign in respiratory care: development of an implementation-ready intervention to improve guideline-adherent adult asthma care across primary and secondary care settings (The SENTINEL Project).

Experiences of staff providing specialist palliative care during COVID-19: a multiple qualitative case study (2022)
Journal Article
Bradshaw, A., Dunleavy, L., Garner, I., Preston, N., Bajwah, S., Cripps, R., …CovPall study team. (in press). Experiences of staff providing specialist palliative care during COVID-19: a multiple qualitative case study. Journal of the Royal Society of Medicine, https://doi.org/10.1177/01410768221077366

Objective: To explore the experiences of, and impact on, staff working in palliative care during the COVID-19 pandemic. Design: Qualitative multiple case study using semi-structured interviews between November 2020 and April 2021 as part of the CovPa... Read More about Experiences of staff providing specialist palliative care during COVID-19: a multiple qualitative case study.

Conceptualising effective symptom management in palliative care: a novel model derived from qualitative data (2022)
Journal Article
Chapman, E. J., Pini, S., Edwards, Z., Elmokhallalati, Y., Murtagh, F. E., & Bennett, M. I. (2022). Conceptualising effective symptom management in palliative care: a novel model derived from qualitative data. BMC Palliative Care, 21(1), Article 17. https://doi.org/10.1186/s12904-022-00904-9

BACKGROUND: Pain, breathlessness and fatigue are some of the most challenging symptoms to manage in patients with advanced disease. Specialist palliative care leads to better symptom management, but factors contributing to successful symptom manageme... Read More about Conceptualising effective symptom management in palliative care: a novel model derived from qualitative data.

Concurrent validity and prognostic utility of the Needs Assessment Tool: Progressive Disease Heart Failure (2022)
Journal Article
King, C., Khamis, A., Ross, J., Murtagh, F. E., Johnson, M. J., & Ramsenthaler, C. (in press). Concurrent validity and prognostic utility of the Needs Assessment Tool: Progressive Disease Heart Failure. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2022.01.014

Context: People with advanced heart failure have supportive and palliative needs requiring systematic assessment. Objectives: We aimed to assess the validity of the Needs Assessment Tool: Progressive Disease – Heart Failure (NAT:PD-HF). Methods: Seco... Read More about Concurrent validity and prognostic utility of the Needs Assessment Tool: Progressive Disease Heart Failure.

Do guidelines influence breathlessness management in advanced lung diseases? A multinational survey of respiratory medicine and palliative care physicians (2022)
Journal Article
Krajnik, M., Hepgul, N., Wilcock, A., Jassem, E., Bandurski, T., Tanzi, S., …Walker, F. (2022). Do guidelines influence breathlessness management in advanced lung diseases? A multinational survey of respiratory medicine and palliative care physicians. BMC Pulmonary Medicine, 22(1), Article 41. https://doi.org/10.1186/s12890-022-01835-0

Background: Respiratory medicine (RM) and palliative care (PC) physicians’ management of chronic breathlessness in advanced chronic obstructive pulmonary disease (COPD), fibrotic interstitial lung disease (fILD) and lung cancer (LC), and the influenc... Read More about Do guidelines influence breathlessness management in advanced lung diseases? A multinational survey of respiratory medicine and palliative care physicians.

Development of guidelines to reduce, handle and report missing data in palliative care trials: A multi-stakeholder modified nominal group technique (2022)
Journal Article
Hussain, J. A., White, I. R., Johnson, M. J., Byrne, A., Preston, N. J., Haines, A., …Peters, T. J. (2022). Development of guidelines to reduce, handle and report missing data in palliative care trials: A multi-stakeholder modified nominal group technique. Palliative medicine, 36(1), 59-70. https://doi.org/10.1177/02692163211065597

Background: Missing data can introduce bias and reduce the power, precision and generalisability of study findings. Guidelines on how to address missing data are limited in scope and detail, and poorly implemented. Aim: To develop guidelines on how b... Read More about Development of guidelines to reduce, handle and report missing data in palliative care trials: A multi-stakeholder modified nominal group technique.

Understanding the impact of the Covid-19 pandemic on delivery of rehabilitation in specialist palliative care services: An analysis of the CovPall-Rehab survey data (2021)
Journal Article
Bayly, J., Bradshaw, A., Fettes, L., Omarjee, M., Talbot-Rice, H., Walshe, C., …Maddocks, M. (in press). Understanding the impact of the Covid-19 pandemic on delivery of rehabilitation in specialist palliative care services: An analysis of the CovPall-Rehab survey data. Palliative medicine, https://doi.org/10.1177/02692163211063397

Background: Palliative rehabilitation involves multi-professional processes and interventions aimed at optimising patients’ symptom self-management, independence and social participation throughout advanced illness. Rehabilitation services were highl... Read More about Understanding the impact of the Covid-19 pandemic on delivery of rehabilitation in specialist palliative care services: An analysis of the CovPall-Rehab survey data.

Communication of poor prognosis between secondary and primary care: protocol for a systematic review with narrative synthesis (2021)
Journal Article
Pocock, L. V., Purdy, S., Barclay, S., Murtagh, F. E., & Selman, L. E. (2021). Communication of poor prognosis between secondary and primary care: protocol for a systematic review with narrative synthesis. BMJ open, 11(12), Article e055731. https://doi.org/10.1136/bmjopen-2021-055731

Introduction People dying in Britain spend, on average, 3 weeks of their last year of life in hospital. Hospital discharge presents an opportunity for secondary care clinicians to communicate to general practitioners (GPs) which patients may have a p... Read More about Communication of poor prognosis between secondary and primary care: protocol for a systematic review with narrative synthesis.

Change in Activity of Palliative Care Services during the Covid-19 Pandemic: A Multinational Survey (CovPall) (2021)
Journal Article
Sleeman, K. E., Cripps, R. L., Murtagh, F. E., Oluyase, A. O., Hocaoglu, M. B., Maddocks, M., …on behalf of the CovPall Study Team. (2022). Change in Activity of Palliative Care Services during the Covid-19 Pandemic: A Multinational Survey (CovPall). Journal of palliative medicine, 25(3), 465-471. https://doi.org/10.1089/jpm.2021.0315

Objectives: To identify factors associated with palliative care services being busier during Covid-19. Methods: Cross-sectional online survey of UK palliative care services (April to July 2020) (CovPall). Ethical approval was received from King's Col... Read More about Change in Activity of Palliative Care Services during the Covid-19 Pandemic: A Multinational Survey (CovPall).