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Factors Associated With Normal Physiologic Birth for Women Who Labor In Water: A Secondary Analysis of A Prospective Observational Study (2022)
Journal Article
Carpenter, J., Burns, E., & Smith, L. (2022). Factors Associated With Normal Physiologic Birth for Women Who Labor In Water: A Secondary Analysis of A Prospective Observational Study. Journal of Midwifery and Women's Health, 67(1), 13-20. https://doi.org/10.1111/jmwh.13315

Introduction: Research to understand factors associated with normal physiologic birth (unassisted vaginal birth, spontaneous labor onset without epidural analgesia, spinal, or general anesthetic, without episiotomy) is required. Laboring and/or givin... Read More about Factors Associated With Normal Physiologic Birth for Women Who Labor In Water: A Secondary Analysis of A Prospective Observational Study.

The effects of phytochemicals and herbal bio-active compounds on tumour necrosis factor-α in overweight and obese individuals: a clinical review (2022)
Journal Article
Bagherniya, M., Mahdavi, A., Abbasi, E., Iranshahy, M., Sathyapalan, T., & Sahebkar, A. (2022). The effects of phytochemicals and herbal bio-active compounds on tumour necrosis factor-α in overweight and obese individuals: a clinical review. Inflammopharmacology, 30(1), 91-110. https://doi.org/10.1007/s10787-021-00902-y

Obesity is abnormal fat accumulation in the body which acts as a risk factor for various cardiometabolic states. Adipose tissue in excess can release inflammatory factors, including TNF-α and IL-6, and suppress adiponectin production. TNF-α increases... Read More about The effects of phytochemicals and herbal bio-active compounds on tumour necrosis factor-α in overweight and obese individuals: a clinical review.

Uncomplicated Plasmodium vivax malaria: mapping the proteome from circulating platelets (2022)
Journal Article
Fernández, D., Segura, C., Arman, M., McGill, S., Burchmore, R., & Lopera-Mesa, T. (2022). Uncomplicated Plasmodium vivax malaria: mapping the proteome from circulating platelets. Clinical Proteomics, 19, Article 1. https://doi.org/10.1186/s12014-021-09337-7

Background: Thrombocytopenia is frequent in Plasmodium vivax malaria but the role of platelets in pathogenesis is unknown. Our study explores the platelet (PLT) proteome from uncomplicated P. vivax patients, to fingerprint molecular pathways related... Read More about Uncomplicated Plasmodium vivax malaria: mapping the proteome from circulating platelets.

Recent Advances in Lung Cancer Therapy Based on Nanomaterials: A Review (2022)
Journal Article
Gholami, L., Ivari, J. R., Nasab, N. K., Oskuee, R. K., Sathyapalan, T., & Sahebkar, A. (2023). Recent Advances in Lung Cancer Therapy Based on Nanomaterials: A Review. Current medicinal chemistry, 30(3), 335-355. https://doi.org/10.2174/0929867328666210810160901

Lung cancer is one of the commonest cancers with a significant mortality rate for both genders, particularly in men. Lung cancer is recognized as one of the leading causes of death worldwide, which threatens the lives of over 1.6 million people every... Read More about Recent Advances in Lung Cancer Therapy Based on Nanomaterials: A Review.

Antitumor and Protective Effects of Melatonin: The Potential Roles of MicroRNAs (2022)
Book Chapter
Ashrafizadeh, M., Ahmadi, Z., Yaribeygi, H., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2022). Antitumor and Protective Effects of Melatonin: The Potential Roles of MicroRNAs. In A. Sahebkar, & T. Sathyapalan (Eds.), Natural Products and Human Diseases (463-471). Springer. https://doi.org/10.1007/978-3-030-73234-9_31

MicroRNAs (miRNAs) are endogenous short noncoding RNAs with approximately 22 nucleotides. The primary function of miRNAs is the negative regulation of target gene expression via mRNA degradation or translation inhibition. During recent years, much at... Read More about Antitumor and Protective Effects of Melatonin: The Potential Roles of MicroRNAs.

Barriers and facilitators to accessing and utilising post-treatment psychosocial support by Black men treated for prostate cancer—a systematic review and qualitative synthesis (2022)
Journal Article
Bamidele, O. O., Alexis, O., Ogunsanya, M., Greenley, S., Worsley, A., & Mitchell, E. D. (2022). Barriers and facilitators to accessing and utilising post-treatment psychosocial support by Black men treated for prostate cancer—a systematic review and qualitative synthesis. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, https://doi.org/10.1007/s00520-021-06716-6

Purpose: To synthesise findings from published studies on barriers and facilitators to Black men accessing and utilising post-treatment psychosocial support after prostate cancer (CaP) treatment.
Methods: Searches of Medline, Embase, PsycInfo, Coch... Read More about Barriers and facilitators to accessing and utilising post-treatment psychosocial support by Black men treated for prostate cancer—a systematic review and qualitative synthesis.

Geographical distance and reduced access to palliative radiotherapy: Systematic review and meta-analysis (2022)
Journal Article
Chand, C. P., Greenley, S., Macleod, U., Lind, M., Barton, R., & Kelly, C. (2022). Geographical distance and reduced access to palliative radiotherapy: Systematic review and meta-analysis. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2021-003356

Background: Palliative radiotherapy (PRT) is an effective way of reducing symptoms caused by advanced incurable cancer. Several studies have investigated factors that contribute to inequalities in access to PRT; distance to a radiotherapy centre has... Read More about Geographical distance and reduced access to palliative radiotherapy: Systematic review and meta-analysis.

Quantitative Scintigraphy Evaluated the Relationship between 131I Therapy and Salivary Glands Function in DTC Patients: A Retrospective Analysis (2022)
Journal Article
Lv, X., Yin, L., Wu, W., Li, N., Zhang, R., Li, X., Jia, Q., Tan, J., Wang, P., Zheng, X., He, X., Huang, C., Li, D., Wang, Y., & Meng, Z. (2022). Quantitative Scintigraphy Evaluated the Relationship between 131I Therapy and Salivary Glands Function in DTC Patients: A Retrospective Analysis. Journal of Healthcare Engineering, 2022, Article 7640405. https://doi.org/10.1155/2022/7640405

Purpose. Quantitative scintigraphy to evaluate salivary gland function changes in patients with differentiated thyroid cancer (DTC) after iodine-131 (131I) treatment. Methods. A total of 458 patients with DTC grouped by sex and age were included. Sal... Read More about Quantitative Scintigraphy Evaluated the Relationship between 131I Therapy and Salivary Glands Function in DTC Patients: A Retrospective Analysis.

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 2b Trial of P2X3 Receptor Antagonist Sivopixant for Refractory or Unexplained Chronic Cough (2022)
Journal Article
McGarvey, L., Smith, J. A., Morice, A., Birring, S. S., Chung, K. F., Dicpinigaitis, P. V., Niimi, A., Benninger, M. S., Sher, M., Matsunaga, Y., Miyazaki, S., Machida, M., Ishihara, H., Mahmood, A., & Gomez, J. C. (2022). A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 2b Trial of P2X3 Receptor Antagonist Sivopixant for Refractory or Unexplained Chronic Cough. Lung, https://doi.org/10.1007/s00408-022-00592-5

Introduction: To determine the optimal dose of sivopixant, a highly selective P2X3 receptor antagonist, for refractory or unexplained chronic cough (RCC/UCC). Methods: In this phase 2b, randomized, double-blind, placebo-controlled, parallel-group, mu... Read More about A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 2b Trial of P2X3 Receptor Antagonist Sivopixant for Refractory or Unexplained Chronic Cough.

European respiratory society guidelines on the diagnosis and treatment of chronic cough in adults and children (2021)
Journal Article
Morice, A. H., Millqvist, E., Bieksiene, K., Birring, S. S., Dicpinigaitis, P., Ribas, C. D., Boon, M. H., Kantar, A., Lai, K., McGarvey, L., Rigau, D., Satia, I., Smith, J., Song, W. J., Tonia, T., van den Berg, J. W., van Manen, M. J., & Zacharasiewicz, A. (2021). European respiratory society guidelines on the diagnosis and treatment of chronic cough in adults and children. Pulmonologiya, 31(4), 418-438. https://doi.org/10.18093/0869-0189-2021-31-4-418-438

These guidelines incorporate the recent advances in chronic cough pathophysiology, diagnosis and treatment. The concept of cough hypersensitivity has allowed an umbrella term that explains the exquisite sensitivity of patients to external stimuli suc... Read More about European respiratory society guidelines on the diagnosis and treatment of chronic cough in adults and children.

Understanding the impact of the Covid-19 pandemic on delivery of rehabilitation in specialist palliative care services: An analysis of the CovPall-Rehab survey data (2021)
Journal Article
Bayly, J., Bradshaw, A., Fettes, L., Omarjee, M., Talbot-Rice, H., Walshe, C., Sleeman, K. E., Bajwah, S., Dunleavy, L., Hocaoglu, M., Oluyase, A., Garner, I., Cripps, R. L., Preston, N., Fraser, L. K., Murtagh, F. E., Higginson, I. J., & Maddocks, M. (in press). Understanding the impact of the Covid-19 pandemic on delivery of rehabilitation in specialist palliative care services: An analysis of the CovPall-Rehab survey data. Palliative medicine, https://doi.org/10.1177/02692163211063397

Background: Palliative rehabilitation involves multi-professional processes and interventions aimed at optimising patients’ symptom self-management, independence and social participation throughout advanced illness. Rehabilitation services were highl... Read More about Understanding the impact of the Covid-19 pandemic on delivery of rehabilitation in specialist palliative care services: An analysis of the CovPall-Rehab survey data.

Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis (2021)
Journal Article
Featherstone, I., Sheldon, T., Woodhouse, R., Boland, J. W., Hosie, A., Lawlor, P. G., Russell, G., Bush, S. H., Siddiqi, N., & Johnson, M. (in press). Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis. Palliative medicine, https://doi.org/10.1177/02692163211065278

Background: Delirium is common and distressing for patients receiving palliative care. Interventions targetting modifiable risk factors in other settings have been shown to prevent delirium. Research on delirium risk factors in palliative care can in... Read More about Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis.

Change in Activity of Palliative Care Services during the Covid-19 Pandemic: A Multinational Survey (CovPall) (2021)
Journal Article
Sleeman, K. E., Cripps, R. L., Murtagh, F. E., Oluyase, A. O., Hocaoglu, M. B., Maddocks, M., Walshe, C., Preston, N., Dunleavy, L., Bradshaw, A., Bajwah, S., Higginson, I. J., Fraser, L. K., & on behalf of the CovPall Study Team. (2022). Change in Activity of Palliative Care Services during the Covid-19 Pandemic: A Multinational Survey (CovPall). Journal of palliative medicine, 25(3), 465-471. https://doi.org/10.1089/jpm.2021.0315

Objectives: To identify factors associated with palliative care services being busier during Covid-19. Methods: Cross-sectional online survey of UK palliative care services (April to July 2020) (CovPall). Ethical approval was received from King's Col... Read More about Change in Activity of Palliative Care Services during the Covid-19 Pandemic: A Multinational Survey (CovPall).

Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations (2021)
Journal Article
Crane, H., Boam, G., Carradice, D., Vanicek, N., Twiddy, M., & Smith, G. E. (2021). Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations. The Cochrane database of systematic reviews, 2021(12), CD013839. https://doi.org/10.1002/14651858.CD013839.pub2

BACKGROUND: Diabetes and vascular disease are the leading causes of lower limb amputation. Currently, 463 million adults are living with diabetes, and 202 million with peripheral vascular disease, worldwide. When a lower limb amputation is considered... Read More about Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations.

Prevalence and severity of differing dimensions of breathlessness among elderly males in the population (2021)
Journal Article
Olsson, M., Currow, D. C., Johnson, M. J., Sandberg, J., Engström, G., & Ekstrom, M. (2022). Prevalence and severity of differing dimensions of breathlessness among elderly males in the population. ERJ Open Research, 8(1), https://doi.org/10.1183/23120541.00553-2021

Breathlessness is common in the general population. Existing data were obtained primarily with the uni-dimensional modified Medical Research Council breathlessness scale (mMRC) that does not assess intensities of unpleasantness nor physical, emotiona... Read More about Prevalence and severity of differing dimensions of breathlessness among elderly males in the population.

Factors associated with the timing and number of antenatal care visits among unmarried compared to married youth in uganda between 2006 and 2016 (2021)
Journal Article
Agaba, P., Onukwugha, F., Magadi, M., & Misinde, C. (2021). Factors associated with the timing and number of antenatal care visits among unmarried compared to married youth in uganda between 2006 and 2016. Social Sciences, 10(12), Article 474. https://doi.org/10.3390/socsci10120474

Antenatal care is an important determinant of pregnancy and childbirth outcomes. Although the youth disproportionately experience adverse maternal complications and poor pregnancy outcomes, including maternal mortality, timely and frequent use of ant... Read More about Factors associated with the timing and number of antenatal care visits among unmarried compared to married youth in uganda between 2006 and 2016.

Potential Biomarkers to Predict Acute Ischemic Stroke in Type 2 Diabetes (2021)
Journal Article
Moin, A. S. M., Nandakumar, M., Al-Qaissi, A., Sathyapalan, T., Atkin, S. L., & Butler, A. E. (2021). Potential Biomarkers to Predict Acute Ischemic Stroke in Type 2 Diabetes. Frontiers in Molecular Biosciences, 8, Article 744459. https://doi.org/10.3389/fmolb.2021.744459

Background and Purpose: Patients with type 2 diabetes (T2D) have increased risk of cardiovascular disease (CVD), encompassing myocardial infarction, stroke, and peripheral vascular disease. We hypothesized that those biomarkers indicative of acute is... Read More about Potential Biomarkers to Predict Acute Ischemic Stroke in Type 2 Diabetes.

Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia (2021)
Journal Article
Naylor-Adamson, L., Chacko, A., Booth, Z., Caserta, S., Jarvis, J., Khan, S., Hart, S. P., Rivero, F., Allsup, D. J., & Arman, M. (2021). Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia. Frontiers in immunology, 12, Article 766272. https://doi.org/10.3389/fimmu.2021.766272

Bacterial infections are a major cause of morbidity and mortality in chronic lymphocytic leukemia (CLL), and infection risk increases in patients treated with the Bruton’s tyrosine kinase (Btk) inhibitor, ibrutinib. Btk and related kinases (like Tec)... Read More about Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia.