Understanding barriers and facilitators to implementing physical activity interventions for patients receiving immune checkpoint inhibitor therapy: A qualitative study Nov 1, 2023 - Jul 31, 2025
Immune checkpoint inhibitors (ICIs) have huge potential for the treatment of metastatic melanoma, renal, head and neck, and lung cancers. While recent research shows that exercise improves chemoradiotherapy outcomes, its role as an adjunctive treatme...
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Professor Mark Pearson's Projects (23)
HEIF: QR Policy Development Fund project Jun 1, 2023 - Jul 31, 2023
North Yorkshire Health Determinants Research Collaboration Jan 1, 2024 - Dec 31, 2028
The NIHR Health Determinants Research Collaboration North Yorkshire is a research infrastructure project to build research capacity within North Yorkshire Council. It will embed a strong research culture to generate robust evidence that will inform s...
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BREEZE 2: A randomised controlled trial of a complex intervention to manage breathlessness in pulmonary fibrosis Apr 1, 2024 - Mar 31, 2026
Full trial based on BREEZE feasibility trial
NIHR Policy Research Unit (PRU) for Palliative and End of Life Care Jan 1, 2024 - Dec 31, 2026
Living well with chronic breathlessness: Improving the sustainable use of supported self-management strategies Mar 1, 2023 - Dec 31, 2024
Chronic (persistent) breathlessness restricts social lives and day-to-day tasks. Breathlessness services can support people to self-manage, but there is often a gap between knowing what to do and doing it - true for patients, carers and clinicians al...
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BREATHE-INDIA: BREATHlEssness in INDIA - Development of a breathlessness beliefs and behaviour education intervention for use in the community-setting Oct 1, 2022 - Mar 31, 2024
PUBLIC HEALTH CHALLENGE: Chronic (persistent) breathlessness despite treatment of causal disease(s) 1 is associated with disability and a vicious cycle of avoiding physical activity-related breathlessness,2 deconditioning and increasing breathlessnes...
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Arts for the Blues: Towards integrating arts-based approaches to tackling depression in healthcare settings in the North West Jan 31, 2022 - Jul 30, 2023
In this project we will develop a strategy for making the Arts for the Blues intervention easily available to adults and children struggling with depression, low mood or anxiety. This group therapy uses visual arts, music, dance, drama and creative w...
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SERENITY: Towards cancer patient empowerment for optimal use of antithrombotic therapy at the end of life Oct 1, 2022 - Sep 30, 2027
Supporting, enabling and sustaining home care workers to deliver end-of-life care: amultiple-methods community-based case study Oct 1, 2022 - Jul 14, 2025
This 30 month study will;
1) To understand the experience of social care assistants providing end of life care, the care they give, how they work with healthcare staff and family members or friends, and what all involved (including the person receiv...
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A phase II, randomised feasibility trial of a tailored, home-based exercise programme on disease-free survival among early stage high-risk recurring cancers in Yorkshire Sep 1, 2022 - Aug 31, 2026
To determine the effect exercise has on preventing secondary cancers and improving 5-year survival rates among people diagnosed with breast, bowel, lung, or prostate cancers in Yorkshire.
Adapting a smartphone-based rehabilitation programme for older adults living with and beyond cancer: an intervention development study Apr 1, 2022 - Apr 30, 2024
The number of people living with and beyond cancer is growing; many are over 65 years old who often have different and more complicated healthcare needs than younger people.
Being active is one of the best things people with, or who have had, canc...
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TRANSFORM: Detecting, preventing, and managing delirium in specialist palliative care units: Co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care Feb 15, 2021 - Dec 31, 2023
Systematic identification, assessment and management of delirium, common in cancer, is crucial; causes may be reversible, preventing further deterioration and death. Currently clinical guidelines are not implemented in hospices. A relevant and flexib...
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PrimaryBreathe: programme to develop and test a brief remote primary care intervention for chronic breathlessness Sep 1, 2022 - Aug 31, 2027
Breathlessness affects the daily lives of one in ten adults and a quarter of those aged over 70. The number of people experiencing breathlessness is growing worldwide as long-term health conditions, like heart or lung disease, become more common. COV...
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Strategies to address unprofessional behaviours among staff in acute healthcare settings: a realist review Oct 1, 2021 - Dec 31, 2022
The unprofessional behaviours of healthcare staff towards each other are known to be widespread. In poor workplace cultures such behaviours can be considered ‘normal’. Yet they significantly affect an individual’s ability to work without fear and spe...
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I3: Building Critical Mass, Increasing Scale and Impact for Palliative Care through International Collaboration Aug 1, 2019 - Mar 31, 2025
The world population is ageing and, with the growth of multi-morbidities, UK deaths are expected to increase by 40% by 2040. New models of care and treatments are urgently needed to improve quality of life for the significantly increased numbers of p...
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APPEAL: Antenatal Prophylactic Pelvic floor Exercises And Localisation Programme Nov 27, 2017 - Sep 30, 2022
Antenatal Prophylactic Pelvic floor Exercises And Localisation (APPEAL) brings together a programme of research to prevent poor health linked to pregnancy and childbirth-related urinary incontinence. The aim of APPEALis to increase the number of wom...
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