Professor Ross Boyle R.W.Boyle@hull.ac.uk
Professor of Biological Chemistry
Triggering the anti‐cancer immune response by combined radio‐ photodynamic‐ therapy of liver tumours
People Involved
Dr Grazia Francesconi
Project Description
The majority of deaths from cancer are not caused by the primary tumour, but by secondary metastases. The liver ranks second only to the lymph nodes, as the most common site where metastatic tumours develop. Worldwide 700,000 people are diagnosed with liver cancer annually and 600,000 of these will die of the disease (American Cancer Society 2012). Patients with liver metastases are currently treated in a number of ways depending on the site and stage of the tumour, however, only 10-25% of patients meet the criteria for surgical resection, and while systemic chemotherapy has a response rate of 20-40%, it has little effect on long term survival. We propose to address these depressing statistics by developing a radical new therapy with the potential to treat primary tumours while simultaneously mobilising the immune system to attack metastases at distant sites in the body.
| Type of Project | Standard |
|---|---|
| Status | Project Complete |
| Funder(s) | Castle Hill Hospital Cancer Trust Fund |
| Value | £15,000.00 |
| Project Dates | Sep 1, 2014 - Dec 31, 2024 |
You might also like
Photo-activated surface coatings to combat bacterial contamination Oct 1, 2019 - May 31, 2023
Antimicrobial materials have received much interest recently. The efficient inactivation of pathogenic bacteria on surfaces is one of the major challenges in the management of infection. Our project seeks to develop a cost effective and versatile pol...
Read More about Photo-activated surface coatings to combat bacterial contamination.
Novel Radiation Enhancing Compounds Jan 1, 2016 - Dec 31, 2025
Luminescent C-Dots: Fabrication, Characterization And Application As Potential Photocatalyst And Fluorescent Sensor Feb 28, 2018 - Mar 31, 2019
Wastewater streams are a serious environmental concern because of the risks of discharging poorly treated effluents directly into the environment by posing a pollution threat to all receiving water bodies, groundwater pollution, soil contamination an...
Read More about Luminescent C-Dots: Fabrication, Characterization And Application As Potential Photocatalyst And Fluorescent Sensor.
Anion-Deficient Solids for CO2 Capture – Towards New Materials Jun 4, 2018 - Jul 27, 2018
This project is closely linked to Jon’s two career goals (completing research in materials and in green chemistry) as would be gaining experience in creating and characterising new materials. As well as using CO2 in their synthesis, as materials that...
Read More about Anion-Deficient Solids for CO2 Capture – Towards New Materials.
Pollutants and greenhouse gases in the atmosphere - understanding gas-gas and gas-solid interactions towards a cleaner atmosphere ATMOS Dec 1, 2021 - Jan 31, 2026
ATMOS denotes a consortium of eleven scientific institutions, six beneficiaries and five partners which main objective is to establish a collaborative effort for the study of scientific problems related to the atmosphere pollution elements, with an e...
Read More about Pollutants and greenhouse gases in the atmosphere - understanding gas-gas and gas-solid interactions towards a cleaner atmosphere ATMOS.