Outputs (3837)

Impact of increasing the availability of healthier vs. less-healthy food on food selection: a randomised laboratory experiment (2021)
Journal Article
Pechey, R., Sexton, O., Codling, S., & Marteau, T. M. (2021). Impact of increasing the availability of healthier vs. less-healthy food on food selection: a randomised laboratory experiment. BMC public health, 21(1), Article 132. https://doi.org/10.1186/s12889-020-10046-3

Background
Environmental cues shape behaviour, but few studies compare the impact of targeting healthier vs. less-healthy cues. One online study suggested greater impact on selection from increasing the number of less-healthy (vs. healthier) snacks.... Read More about Impact of increasing the availability of healthier vs. less-healthy food on food selection: a randomised laboratory experiment.

A double-blind randomized controlled trial for the effects of dry needling on upper limb dysfunction in patients with stroke (2021)
Journal Article
Tavakol, Z., Shariat, A., Ansari, N., Ghannadi, S., Honarpishe, R., Dommerholt, J., Noormohammadpour, P., & Ingle, L. (2021). A double-blind randomized controlled trial for the effects of dry needling on upper limb dysfunction in patients with stroke. Acupuncture and Electro-Therapeutics Research, 45(2-4), 115-124. https://doi.org/10.3727/036012921X16112663844923

Spasticity is one of the main complications of a stroke. This double-blind, randomized controlled trial aimed to compare the result of three sessions of dry needling (DN) versus sham DN on the affected upper limbs in post-stroke survivors. We recruit... Read More about A double-blind randomized controlled trial for the effects of dry needling on upper limb dysfunction in patients with stroke.

Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models (2021)
Journal Article
Mohammadi, S., Abdollahi, E., Nezamnia, M., Esmaeili, S. A., Tavasolian, F., Sathyapalan, T., & Sahebkar, A. (2021). Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models. International immunopharmacology, 90, Article 107195. https://doi.org/10.1016/j.intimp.2020.107195

Since half of the genes are inherited from the paternal side, the maternal immune system has to tolerate the presence of foreign paternal antigens. Regulatory T cells facilitate the development and maintenance of peripheral tissue tolerance of the fe... Read More about Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models.

Comment on Moody: ‘“Advance” Care Planning Re‐envisioned’ (2021)
Journal Article
Bradshaw, A., Bayly, J., Penfold, C., Lin, C., Oluyase, A. O., Hocaoglu, M. B., Murtagh, F. E., & Koffman, J. (in press). Comment on Moody: ‘“Advance” Care Planning Re‐envisioned’. Journal of the American Geriatrics Society, https://doi.org/10.1111/jgs.17058

Preexposure along a continuum: Differentiation and association. (2021)
Journal Article
George, D. N., & Haddon, J. E. (2021). Preexposure along a continuum: Differentiation and association. Journal of Experimental Psychology: Animal Learning and Cognition, 47(1), 48-62. https://doi.org/10.1037/xan0000266

In 5 experiments, we assessed the effects of preexposure to simple auditory stimuli on subsequent conditioning and discrimination learning. Experiment 1 showed that preexposure to a single stimulus retarded acquisition of conditioned responding to th... Read More about Preexposure along a continuum: Differentiation and association..

Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study (2021)
Journal Article
Genberg, J., Davies, J. M., Ahmadi, Z., Currow, D., Johnson, M. J., Tanash, H., Bajwah, S., & Ekström, M. (2021). Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study. ERJ Open Research, 7(1), 1-7. https://doi.org/10.1183/23120541.00716-2020

Background: Despite evidence that opioids might relieve chronic breathlessness, physicians may still be reluctant to prescribe them due to safety concerns. By contrast, benzodiazepine (BDZ) prescribing often seeks to reduce chronic breathlessness des... Read More about Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study.

Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia (2021)
Journal Article
Lin, W. Y., Fordham, S. E., Sunter, N., Elstob, C., Rahman, T., Willmore, E., Shepherd, C., Strathdee, G., Mainou-Fowler, T., Piddock, R., Mearns, H., Barrow, T., Houlston, R. S., Marr, H., Wallis, J., Summerfield, G., Marshall, S., Pettitt, A., Pepper, C., Fegan, C., …Allan, J. M. (2021). Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia. Nature communications, 12(1), Article 665. https://doi.org/10.1038/s41467-020-20822-9

© 2021, The Author(s). Prognostication in patients with chronic lymphocytic leukemia (CLL) is challenging due to heterogeneity in clinical course. We hypothesize that constitutional genetic variation affects disease progression and could aid prognost... Read More about Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia.

The potential role of incretin-based therapies for polycystic ovary syndrome: a narrative review of the current evidence (2021)
Journal Article
Abdalla, M. A., Deshmukh, H., Atkin, S., & Sathyapalan, T. (2021). The potential role of incretin-based therapies for polycystic ovary syndrome: a narrative review of the current evidence. Therapeutic Advances in Endocrinology and Metabolism, 12, https://doi.org/10.1177/2042018821989238

© The Author(s), 2021. Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects women of reproductive age. Metabolic consequences associated with PCOS include, but are not limited to, insulin resistance (IR), type 2... Read More about The potential role of incretin-based therapies for polycystic ovary syndrome: a narrative review of the current evidence.

Author response to: Comment on: Patterns of acute surgical inflammatory processes presentation of in the COVID-19 outbreak (PIACO Study): surgery may be the best treatment option (2021)
Journal Article
Guadalajara, H., Muñoz de Nova, J. L., Fernandez Gonzalez, S., Yiasemidou, M., Recarte Rico, M., Juez, L. D., García Septiem, J., Galindo Jara, P., García Virosta, M., Lobo Martínez, E., Martín-Pérez, E., García-Olmo, D., Fernández-Cebrián, J. M., Blazquez Martin, A., Jover, J. M., Iparraguirre, M. A., Acín-Gándara, D., Perea-del-Pozo, E., Dios-Barbeito, S., Martin-Antona, E., …PIACO Collaboration Group. (2021). Author response to: Comment on: Patterns of acute surgical inflammatory processes presentation of in the COVID-19 outbreak (PIACO Study): surgery may be the best treatment option. British journal of surgery, 108(1), e42-e43. https://doi.org/10.1093/bjs/znaa022

‘When I asked for help and support it was not there’: current NHS employment practice and its impact on people with systemic lupus erythematosus (2021)
Journal Article
Booth, S., Price, E., & Walker, E. (2021). ‘When I asked for help and support it was not there’: current NHS employment practice and its impact on people with systemic lupus erythematosus. Rheumatology Advances in Practice, 5(1), Article rkab019. https://doi.org/10.1093/rap/rkab019

Objectives
The aim was to investigate whether National Health Service (NHS) employees with SLE, for whom work disability and early retirement are high, are supported effectively in at work.
Methods
An online survey of 393 people with lupus was com... Read More about ‘When I asked for help and support it was not there’: current NHS employment practice and its impact on people with systemic lupus erythematosus.

A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol (2021)
Journal Article
Northgraves, M., Cohen, J., Allgar, V., Currow, D., Hart, S., Hird, K., Hodge, A., Johnson, M., Mason, S., Swan, F., & Hutchinson, A. (2021). A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol. ERJ Open Research, 7(1), Article 00955-2020. https://doi.org/10.1183/23120541.00955-2020

Introduction: Chronic breathlessness, persistent and disabling despite optimal treatment of underlying causes, is a prevalent and frightening symptom and is associated with many emergency presentations and admission to hospital. Breathlessness manage... Read More about A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol.

Radical Cystectomy Against Intravesical BCG for High-Risk High-Grade Nonmuscle Invasive Bladder Cancer: Results From the Randomized Controlled BRAVO-Feasibility Study (2021)
Journal Article
Brown, J. M., Croft, J., Poad, H., Bell, R., Collinson, M., Gordon, K., Dooldeniya, M., Conroy, S., Catto, J. W., Noon, A. P., Simms, M., Chahal, R., Jain, S., Koenig, P., Johnson, M., Twiddy, M., & Goodwin, L. (2021). Radical Cystectomy Against Intravesical BCG for High-Risk High-Grade Nonmuscle Invasive Bladder Cancer: Results From the Randomized Controlled BRAVO-Feasibility Study. Journal of Clinical Oncology, 39(3), 202-214. https://doi.org/10.1200/JCO.20.01665

PURPOSE: High-grade nonmuscle invasive bladder cancer (HRNMIBC) is a heterogeneous disease. Treatments include intravesical maintenance Bacillus Calmette-Guerin (mBCG) and radical cystectomy (RC). We wanted to understand whether a randomized trial co... Read More about Radical Cystectomy Against Intravesical BCG for High-Risk High-Grade Nonmuscle Invasive Bladder Cancer: Results From the Randomized Controlled BRAVO-Feasibility Study.

Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations (Protocol) (2021)
Journal Article
Crane, H., Boam, G., Carradice, D., Vanicek, N., Twiddy, M., & Smith, G. E. (2021). Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations (Protocol). Cochrane Database of Systematic Reviews, 2021(1), Article CD013839. https://doi.org/10.1002/14651858.CD013839

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the effects of through-knee amputation compared to above-knee amputation on clinical and rehabilitation outcomes and complication rates in... Read More about Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations (Protocol).

Multivalency in CXCR4 chemokine receptor targeted iron oxide nanoparticles (2021)
Journal Article
Baghdadi, N. E., Burke, B. P., Alresheedi, T., Nigam, S., Saeed, A., Almutairi, F., Domarkas, J., Khan, A., & Archibald, S. J. (2021). Multivalency in CXCR4 chemokine receptor targeted iron oxide nanoparticles. Dalton Transactions : an international journal of inorganic chemistry, 50(5), 1599-1603. https://doi.org/10.1039/d0dt02626c

The CXCR4 chemokine receptor is an important biomolecular target in cancer diagnostics and therapeutics. In a new multivalent approach, iron oxide nanoparticles were conjugated with multiple binding units of a low affinity azamacrocylic CXCR4 antagon... Read More about Multivalency in CXCR4 chemokine receptor targeted iron oxide nanoparticles.

Studying animal innovation at the individual level: A ratings-based assessment in capuchin monkeys (Sapajus [Cebus] sp.). (2021)
Journal Article
Morton, F. B., Buchanan-Smith, H. M., Brosnan, S. F., Thierry, B., Paukner, A., Essler, J. L., Marcum, C. S., & Lee, P. C. (2021). Studying animal innovation at the individual level: A ratings-based assessment in capuchin monkeys (Sapajus [Cebus] sp.). Journal of Comparative Psychology, 135(2), 258-265. https://doi.org/10.1037/com0000264

Large-scale studies of individual differences in innovative behavior among nonhuman animals are rare because of logistical difficulties associated with obtaining observational data on a large number of innovative individuals across multiple locations... Read More about Studying animal innovation at the individual level: A ratings-based assessment in capuchin monkeys (Sapajus [Cebus] sp.)..

Platelet releasate normalises the compromised muscle regeneration in a mouse model of hyperlipidaemia (2021)
Journal Article
Barlow, J., Sfyri, P. P., Mitchell, R., Verpoorten, S., Scully, D., Andreou, C., Papadopoulos, P., Patel, K., & Matsakas, A. (2021). Platelet releasate normalises the compromised muscle regeneration in a mouse model of hyperlipidaemia. Experimental Physiology, 106(3), 700-713. https://doi.org/10.1113/ep088937

Muscle satellite cells are important stem cells for skeletal muscle regeneration and repair after injury. ApoE‐deficient mice, an established mouse model of hyperlipidaemia and atherosclerosis, show evidence of oxidative stress‐induced lesions and fa... Read More about Platelet releasate normalises the compromised muscle regeneration in a mouse model of hyperlipidaemia.

Subcutaneous furosemide in advanced heart failure: service improvement project (2021)
Journal Article
Birch, F., Boam, E., Parsons, S., Ghosh, J., & Johnson, M. J. (in press). Subcutaneous furosemide in advanced heart failure: service improvement project. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2020-002803

Objectives: In severe heart disease, parenteral administration of loop diuretic is often needed. We present clinical outcomes from episodes of care using subcutaneous continuous infusion of furosemide (CSCI-furosemide).

Methods: Retrospective revi... Read More about Subcutaneous furosemide in advanced heart failure: service improvement project.

Radiological anatomy of the abdomen (2021)
Journal Article
Fang, C., Kane, P., Bazira, P. J., & Ben Cresswell, A. (2021). Radiological anatomy of the abdomen. Surgery (Oxford), 39(2), 61-74. https://doi.org/10.1016/j.mpsur.2020.12.001

Advances in technology have led to significant developments in techniques for imaging the abdominal and pelvic organs, in both the elective and emergency surgical settings. Improvements in the quality and availability of imaging has had a profound ef... Read More about Radiological anatomy of the abdomen.

Improving the Reporting of Primary Care Research: An International Survey of Researchers (2021)
Journal Article
Phillips, W. R., Sturgiss, E., Hunik, L., Glasziou, P. P., olde Hartman, T., Orkin, A., Reeve, J., Russell, G. M., & van Weel, C. (2021). Improving the Reporting of Primary Care Research: An International Survey of Researchers. Journal of the American Board of Family Medicine, 34(1), 12-21. https://doi.org/10.3122/jabfm.2021.01.200266

PURPOSE: To assess opportunities to improve reporting of primary care (PC) research to better meet the needs of its varied users. METHODS: International, interprofessional online survey of PC researchers and users, 2018 to 2019. Respondents used Like... Read More about Improving the Reporting of Primary Care Research: An International Survey of Researchers.

Fetal alcohol spectrum disorders: An overview of current evidence and activities in the UK (2021)
Journal Article
Schölin, L., Mukherjee, R. A., Aiton, N., Blackburn, C., Brown, S., Flemming, K. M., Gard, P. R., Howlett, H., Plant, M., Price, A. D., Shields, J., Smith, L. A., Suttie, M., Zammitt, D. C., & Cook, P. A. (2021). Fetal alcohol spectrum disorders: An overview of current evidence and activities in the UK. Archives of Disease in Childhood, 106(7), 636-640. https://doi.org/10.1136/archdischild-2020-320435

Estimates for the UK suggest that alcohol consumption during pregnancy and prevalence of fetal alcohol spectrum disorder (FASD) - the most common neurodevelopmental condition - are high. Considering the significant health and social impacts of FASD,... Read More about Fetal alcohol spectrum disorders: An overview of current evidence and activities in the UK.