TRANSFORM: Reducing Inequalities in Cancer Outcomes in Yorkshire: Realising our potential for innovation in Diagnosis, Patient Management, Survivorship and Palliative Care Research Sep 1, 2017 - Dec 31, 2026
The death rate is higher in Yorkshire than the rest of England resulting in about 200 extra deaths each year of which more than half are in Hull. There are other significant cancer outcome inequalities between different groups; for example poorer pe...
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Projects (58)
PEOPLE: Primary care and community Engagement to Optimise time to Presentation with Lung cancEr symptoms in HULL Jun 1, 2017 - Jun 30, 2023
More people are diagnosed with and die from lung cancer in Hull than any other place in Yorkshire. Our aim is to improve earlier diagnosis of lung cancer by [1] getting people to see their doctor if they get lung symptoms and [2] getting GPs to refe...
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DRESSINg: DACC in the REduction of Surgical Site INfection Feb 1, 2017 - Jan 31, 2018
A surgical site infection is an infection occurring in the body where surgery has recently taken place. The rates of infection vary according to the type of surgery but may occur in as many as 1 in every 3 or 4 operations. All of these infections cau...
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Development and application of a multi-scale computational model of sarcoidosis to predict therapeutic approaches for non-self-resolving disease Jun 30, 2017 - Aug 31, 2020
An in silico computational model of sarcoidosis
Policy Research Unit (PRU): Cancer Awareness, Screening and Early Diagnosis Jan 1, 2019 - Dec 31, 2023
PUMA: Paediatric early warning system (PEWS): Utilisation and Mortality Avoidance. A prospective, mixed methods, before and after study identifying the evidence base for the core components of an effective PEWS and the development of an implementation package for implementation and use in the UK Oct 1, 2017 - Oct 31, 2018
In 2011 a research study compared the child health outcomes and death rate in the UK with other European countries. It was worrying that UK measures of child health were amongst the worst in Europe. It is not clear why that is and further work needs...
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BRAVO: High grade bladder cancer: a randomised controlled trial of radical cystectomy against intra-vesical immunotherapy – a feasibility study Oct 1, 2017 - Sep 30, 2018
Bladder cancer is a common disease with worse outcomes in Yorkshire than in the rest of the UK. We want to conduct a randomized trial to evaluate the best treatment for aggressive bladder cancer when found at an early stage. This could be complete b...
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LAVA: Thermal ablation versus surgery for patients with colorectal liver metastases Oct 1, 2017 - May 31, 2023
NIFTy: Near Infrared Fluorescence imaging to prevent post-surgical hypoparathyroidism after thyriod surgery - a phase II/III pragmatic, multi-centre rct Oct 1, 2019 - Jul 31, 2024
Parathyroid glands are tiny glands in the neck behind the thyroid gland that control the level of calcium in the blood. More than 12,000 patients undergo thyroid surgery every year in England alone (HES dataset). A common complication of thyroid surg...
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Understanding and improving the quality of primary care for prisoners: a mixed-methods study Aug 1, 2019 - Jul 31, 2022
Compared to community populations, prisoners have significantly poorer health, with higher levels of long-term illness and disability, and mortality. Prisoners need and are entitled to appropriate health care, especially primary care for long-term c...
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CANAssess PC2: Cancer Needs Assessment in Primary Care Jul 1, 2019 - Jan 31, 2025
Phase 3 trial to test the effectiveness of the NAT-C tool in primary care to reduce patient and carer unmet needs
Improving outcomes in patient with diabetic foot disease Jun 1, 2018 - May 31, 2019
Diabetes is the fastest growing health crisis of our time. One person with diabetes dies every 6 seconds. In the UK a new person is diagnosed every 2 minutes and care of diabetes currently costs the NHS £1million per hour, every hour. Diabetes is not...
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LACES 2: A multicentre, randomised controlled trial of Laparoscopic versus Open Colorectal Surgery in the Acute Setting Apr 1, 2020 - Dec 31, 2025
Approximately 30,000 patients undergo an emergency laparotomy within the NHS yearly. An emergency laparotomy is an open operation which is undertaken for a variety of diseases, a third of those are for diseases affecting the large bowel, including co...
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A single arm, open-label exploratory clinical trial of azithromycin in pulmonary sarcoidosis Mar 1, 2019 - Sep 30, 2020
Patients with sarcoidosis need treatment options that improve their disease without causing unacceptable side effects. Currently, steroids tablets are offered for severe sarcoidosis, but side effects can be dangerous and personally distressing, and s...
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I3: Building Critical Mass, Increasing Scale and Impact for Palliative Care through International Collaboration Aug 1, 2019 - Mar 31, 2025
The world population is ageing and, with the growth of multi-morbidities, UK deaths are expected to increase by 40% by 2040. New models of care and treatments are urgently needed to improve quality of life for the significantly increased numbers of p...
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EPaCCS: Electronic Palliative Care Co-ordination Systems (EPaCCS) in end of life care: evaluating their implementation and optimising future service provision. Sep 1, 2020 - Nov 30, 2023
It is not clear how Electronic Palliative Care Co-ordination Systems (EPaCCS) are being implemented across England, what problems healthcare professionals face in using EPaCCS, what views patients and caregivers have on EPaCCS, and how EPaCCS affect...
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PPI for PBP research - Exploring the role, responsibilities and impact of pharmacists working in primary care (GP surgeries) Apr 1, 2019 - Sep 30, 2019
Both local and national initiatives seek to recruit more pharmacists to work in GP practices. Following a successful pilot, NHS England have committed to recruit up to 2000 pharmacists by 2020 to work clinically in general practice settings; this is...
Read More about PPI for PBP research - Exploring the role, responsibilities and impact of pharmacists working in primary care (GP surgeries).
Comparing Outcomes of Through knee and Above knee Amputation Apr 17, 2019 - Dec 31, 2021
Project aims: To explore quality of life and rehabilitation outcomes for through knee (TK) amputees and above knee (AK) amputees.
TK amputation is rarely performed despite documented functional benefits and reports that surgical outcomes for dysv...
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