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Prognostic value of the neutrophil-to-lymphocyte ratio in patients with laryngeal squamous cell carcinoma (2015)
Journal Article
Wong, B. Y. W., Stafford, N. D., Green, V. L., & Greenman, J. (2016). Prognostic value of the neutrophil-to-lymphocyte ratio in patients with laryngeal squamous cell carcinoma. Head & neck, 38(S1), E1903-E1908. https://doi.org/10.1002/hed.24346

© 2015 Wiley Periodicals, Inc.. Background The neutrophil/lymphocyte ratio (NLR) has been found to be predictive of survival outcome in a range of tumors. The purpose of this study was to investigate the prognostic value of pretreatment (NLR) in pati... Read More about Prognostic value of the neutrophil-to-lymphocyte ratio in patients with laryngeal squamous cell carcinoma.

Rho Signaling in Dictyostelium discoideum (2015)
Journal Article
Rivero Crespo, F., & Xiong, H. (2016). Rho Signaling in Dictyostelium discoideum. International review of cell and molecular biology, 322, 61-181. https://doi.org/10.1016/bs.ircmb.2015.10.004

© 2016 Elsevier Inc. Small GTPases of the Rho family are ubiquitous molecular switches involved in the regulation of most actin cytoskeleton dependent processes and many other processes not directly linked to actin. D. discoideum is a well-establishe... Read More about Rho Signaling in Dictyostelium discoideum.

Induction of human regulatory T cells with bacterial superantigens (2015)
Book Chapter
Caserta, S., Taylor, A. L., Terrazzini, N., & Llewelyn, M. J. (2016). Induction of human regulatory T cells with bacterial superantigens. In Superantigens; Methods in Molecular Biology (181-206). https://doi.org/10.1007/978-1-4939-3344-0_16

© Springer Science+Business Media New York 2016. Regulatory T cells (Tregs) that suppress the activation of immune effector cells limit immunopathology and are fast emerging as therapeutic targets for autoimmune and cancer disease. Tools enabling Tre... Read More about Induction of human regulatory T cells with bacterial superantigens.

Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse (2015)
Journal Article
Matsakas, A., Prosdocimo, D. A., Mitchell, R., Collins-Hooper, H., Giallourou, N., Swann, J. R., Potter, P., Epting, T., Jain, M. K., & Patel, K. (2015). Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse. Skeletal muscle, 5(1), Article 38. https://doi.org/10.1186/s13395-015-0063-5

© 2015 Matsakas et al. Background: Obese adults are prone to develop metabolic and cardiovascular diseases. Furthermore, over-weight expectant mothers give birth to large babies who also have increased likelihood of developing metabolic and cardiovas... Read More about Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse.

Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis (2015)
Journal Article
Frame, F. M., Savoie, H., Bryden, F., Giuntini, F., Mann, V. M., Simms, M. S., Boyle, R. W., & Maitland, N. J. (2016). Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis. Cancer medicine, 5(1), 61-73. https://doi.org/10.1002/cam4.553

In comparison to more differentiated cells, prostate cancer stem-like cells are radioresistant, which could explain radio-recurrent prostate cancer. Improvement of radiotherapeutic efficacy may therefore require combination therapy. We have investiga... Read More about Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis.

Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces (2015)
Journal Article
Caley, M. P., King, H., Shah, N., Wang, K., Rodriguez-Teja, M., Gronau, J. H., Waxman, J., & Sturge, J. (2016). Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces. Clinical & experimental metastasis, 33(2), 151-165. https://doi.org/10.1007/s10585-015-9765-7

The diverse composition and structure of extracellular matrix (ECM) interfaces encountered by tumor cells at secondary tissue sites can influence metastatic progression. Extensive in vitro and in vivo data has confirmed that metastasizing tumor cells... Read More about Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.

Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin (2015)
Journal Article
Entract, G. M., Bryden, F., Domarkas, J., Savoie, H., Allott, L., Archibald, S. J., Cawthorne, C., & Boyle, R. W. (2015). Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin. Molecular pharmaceutics, 12(12), 4414-4423. https://doi.org/10.1021/acs.molpharmaceut.5b00606

Synthesis of the first water-soluble porphyrin radiolabeled with fluorine-18 is described: a new molecular theranostic agent which integrates the therapeutic selectivity of photodynamic therapy (PDT) with the imaging efficacy of positron emission tom... Read More about Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin.

Medical therapy, percutaneous coronary intervention and prognosis in patients with chronic total occlusions (2015)
Journal Article
Ladwiniec, A., Allgar, V., Thackray, S., Alamgir, F., & Hoye, A. (2015). Medical therapy, percutaneous coronary intervention and prognosis in patients with chronic total occlusions. Heart, 101(23), 1907-1914. https://doi.org/10.1136/heartjnl-2015-308181

Objective There is little published data reporting outcomes for those found to have a chronic total coronary occlusion (CTO) that is electively treated medically versus those treated by percutaneous coronary intervention (PCI). We sought to compare l... Read More about Medical therapy, percutaneous coronary intervention and prognosis in patients with chronic total occlusions.

Sensitivity of the mussel Mytilus edulis to substrate‑borne vibration in relation to anthropogenically generated noise (2015)
Journal Article
Roberts, L., Cheesman, S., Breithaupt, T., & Elliott, M. (2015). Sensitivity of the mussel Mytilus edulis to substrate‑borne vibration in relation to anthropogenically generated noise. Marine ecology progress series, 538, 185-195. https://doi.org/10.3354/meps11468

© 2015 Inter-Research. Many anthropogenic activities in the oceans involve direct contact with the seabed (for example pile driving), creating radiating particle motion waves. However, the consequences of these waveforms to marine organisms are large... Read More about Sensitivity of the mussel Mytilus edulis to substrate‑borne vibration in relation to anthropogenically generated noise.