Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis

Pymer, Sean A.; Tew, Garry A; Palmer, Joanne; Ingle, Lee; Smith, George E.; Chetter, Ian C.; Harwood, Amy E

Abstract

Background: The aim of this updated review is to consider the evidence base for the effectiveness of home-based exercise programmes as a treatment option for improving walking distance in patients with intermittent claudication. Methods: The Medline, EMBASE, CINAHL, PEDro and Cochrane CENTRAL databases will be searched for terms including ‘intermittent claudication’, ‘peripheral arterial disease’, ‘home-based exercise’ and ‘home-based walking’. No date restrictions will be used but only articles in the English language will be included. Both randomised and non-randomised trials of home-based exercise programmes versus a comparator arm will be included, and a meta-analysis using only the randomised controlled trials will be attempted if the assumptions of heterogeneity are met. Data extraction will include study details, sample description, intervention description, length of follow-up and outcomes measures. The primary outcome measure is objectively measured maximal walking distance or time, with secondary outcome measures including pain-free walking distance or time, changes in physical activity and quality of life. We will also provide a narrative description of the effective components of a home-based exercise intervention which can aid future recommendations. Conclusion: Overall, this proposed review and meta-analysis aims provide a comprehensive and complete overview of the evidence base for home-based exercise programmes, which can aid clinicians in the management of their patients.

Citation

Pymer, S. A., Tew, G. A., Palmer, J., Ingle, L., Smith, G. E., Chetter, I. C., & Harwood, A. E. (2018). Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis. SAGE Open Medicine, 6, https://doi.org/10.1177/2050312118818295

• Journal Article Type: Article
• Acceptance Date: Nov 16, 2018
• Online Publication Date: Dec 10, 2018
• Publication Date: Dec 1, 2018
• Deposit Date: Nov 27, 2018
• Publicly Available Date: Dec 13, 2018
• Journal: SAGE Open Medicine
• Electronic ISSN: 2050-3121
• Publisher: SAGE Publications
• Peer Reviewed: Peer Reviewed
• Volume: 6
• DOI: https://doi.org/10.1177/2050312118818295
• Keywords: Intermittent Claudication; Peripheral Arterial Disease; Exercise; Home-Based; Walking; Community
• Public URL: https://hull-repository.worktribe.com/output/1162332
• Publisher URL: https://journals.sagepub.com/doi/full/10.1177/2050312118818295
• Contract Date: Nov 27, 2018