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Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis

Ingle, Lee; Pymer, Sean; Tew, Garry A; Palmer, Joanne; Ingle, Lee; Smith, George E; Chetter, Ian; Harwood, Amy E

Authors

Sean Pymer

Garry A Tew

Joanne Palmer

George E Smith

Ian Chetter

Amy E Harwood



Contributors

Sean Pymer
Researcher

Gary Tew
Researcher

Joanne Palmer
Researcher

George E Smith
Researcher

Ian Chetter
Project Manager

Amy Harwood
Researcher

Abstract

Background: The aim of this updated review is to consider the evidence base for the effectiveness of home-based exercise programmes (HEP) as a treatment option for improving walking distance in patients with IC.
Methods: The Medline, EMBASE, CINAHL, PEDro and Cochrane CENTRAL databases will be searched for terms including “intermittent claudication”, “peripheral arterial disease”, “home-based exercise” and “home-based walking”. No date restrictions will be used but only articles in the English language will be included. Both randomised and non-randomised trials of HEP’s versus a comparator arm will be included, and a meta-analysis using only the randomised controlled trials will be attempted if the assumptions of heterogeneity are met.
Data extraction will include study details, sample description, intervention description, length of follow up and outcomes measures. The primary outcome measure is objectively measured maximal walking distance or time, with secondary outcome measures including pain-free walking distance or time, changes in physical activity and quality of life. We will also provide a narrative description of the effective components of a home-based exercise intervention which can aid future recommendations.
Conclusion: Overall, this proposed review and meta-analysis aims to provide a comprehensive and complete overview of the evidence base for HEP’s, which can aid clinicians in the management of their patients.

PROSPERO registration number: CRD42018091248

Journal Article Type Article
Publication Date Dec 10, 2018
Electronic ISSN 2050-3121
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 6
Pages 205031211881829
Series ISSN SAGE Open Medicine
Institution Citation Pymer, S., Tew, G. A., Palmer, J., Ingle, L., Smith, G. E., Chetter, I., & Harwood, A. E. (2018). Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis. SAGE Open Medicine, 6, 205031211881829. doi:10.1177/2050312118818295
DOI https://doi.org/10.1177/2050312118818295
Keywords Intermittent Claudication; Peripheral Arterial Disease; Exercise; Home-Based; Walking; Community
Publisher URL https://journals.sagepub.com/doi/full/10.1177/2050312118818295

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This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).





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